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Philip Morris kauft Hersteller von Inhalatoren

London – Der US-Tabakkonzern Philip Morris will den britischen Hersteller von Inhalatoren, Vectura, kaufen. Philip Morris bietet 1,0 Milliarde Pfund (1,2 Milliarden Euro), teilten beide Unternehmen am vergangenen Freitag mit. (aerzteblatt.de, 12.07.2021)

https://www.aerzteblatt.de/nachrichten/125499/Philip-Morris-kauft-Hersteller-von-Inhalatoren

USA. J&J to stop selling opioids in US, reaches $230 mn settlement with New York

Johnson & Johnson, one of the pharmaceutical giants accused of fueling the deadly US opioid crisis, has reached a settlement with the state of New York for $230 million and confirmed it will stop making or selling opioids in the United States. (MedicalXpress, USA, 26.06.2021)

https://medicalxpress.com/news/2021-06-jj-opioids-mn-settlement-york.html

USA. Opioidvergleich: US-Pharmakonzerne akzeptieren milliardenschwere Zahlungen

New York – In einem wichtigen US-Prozess um süchtig machende Schmerzmittel haben drei Arzneimittelgroßhändler einen milliardenschweren Vergleich mit dem Bundesstaat New York akzeptiert. (aerzteblatt.de, 21.07.2021)

https://www.aerzteblatt.de/nachrichten/125739/Opioidvergleich-US-Pharmakonzerne-akzeptieren-milliardenschwere-Zahlungen

USA. The Origins of the Opioid Epidemic with “Empire of Pain” Author, Patrick Radden Keefe (Podcast)

Bestselling author and investigative journalist Patrick Radden Keefe discusses his latest book, Empire of Pain: The Secret History of the Sackler Dynasty on our podcast Heart of the Matter with Elizabeth Vargas. 

In his book, Patrick tells the story of the family responsible for setting into motion the opioid epidemic. Following his recent testimony before the House Committee on Oversight and Reform about the Sackler family, Patrick joins Elizabeth to discuss the “Don Draper of medical advertising,” how one family created a massive addiction crisis, and what is in store for the Sacklers, who now face numerous lawsuits. (Heart oft he Mater, USA, Juni 2021, transcript and podcast, 47:11)

https://drugfree.org/article/heart-of-the-matter-guest-patrick-radden-keefe/

USA. Purdue Pharma Exit Plan Gains Steam With OK From More States

OxyContin maker Purdue Pharma's plan to reorganize into a new entity that helps combat the U.S. opioid epidemic got a big boost as 15 states that had previously opposed the new business model now support it. (AP – Associated Press, USA, 08.07.2021)

https://www.medscape.com/viewarticle/954404

USA. Major Trial Against Opioid Suppliers Begins in New York

New York’s sweeping lawsuit is the first opioid case in which a jury rather than a judge will decide the outcome. (New York Times, 08.07.2021)

https://www.nytimes.com/2021/06/29/nyregion/opioids-in-new-york.html

Illicit sale of controlled drugs at community pharmacy/medical stores of Punjab, Pakistan: A road to demolition of public health. 

Bashir I, Ahmad M, Jamshaid M, Zaman M. 

Heliyon. 2021 May 20;7(5):e07031. doi: 10.1016/j.heliyon.2021.e07031. PMID: 34095564; PMCID: PMC8165400.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165400/

USA. Suboxone Manufacturer Indivior's Former Chief Executive Officer Sentenced to Jail Time in Connection with Drug Safety Claims 

ABINGDON, VIRGINIA – Shaun Thaxter, the former chief executive officer of Indivior PLC, was sentenced today in U.S. District Court in Abingdon to 6 months in federal prison. He was also ordered to pay a fine of $100,000 and forfeit $500,000.  Thaxter pleaded guilty to a one-count misdemeanor information on June 30, 2020 for his role in causing the introduction into interstate commerce of misbranded shipments of the opioid drug Suboxone Film, a violation of the Federal Food, Drug, and Cosmetic Act. Acting United States Attorney Daniel P. Bubar announced the sentence today. (Department of Justice
U.S. Attorney’s Office, Western District of Virginia, USA, 22.10.2020)

https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/press-releases/suboxone-manufacturer-indiviors-former-chief-executive-officer-sentenced-jail-time-connection-drug

Open-access publisher PLOS pushes to extend clout beyond biomedicine

The publisher will launch five new journals, and has introduced a new business model that aims to spread the cost of publishing more fairly. (Nature, USA, 13.05.2021)

https://www.nature.com/articles/d41586-020-01907-3

USA. The Price of Saving a Life: Naloxone’s Cost Barrier in the US

When I walk into my local pharmacy to pick up a naloxone kit, I don’t need to present a prescription. I don’t even need to state my reason for needing naloxone (I’m an opioid-dependent pain patient and I frequently interview people who use illicit opioids). The pharmacist asks whether I prefer the nasal spray or the injectable version, then takes me through a five-minute orientation, explaining how to use it to save someone else’s life. Then I leave with my kit.

No money changes hands. I owe nothing. My choice of injectable versus nasal spray is driven by my own comfort, not by their respective costs. 

I live in Toronto. But in the United States, where the crisis of opioid-involved overdose deaths is raging (as it is in Canada) beyond anything we’ve seen before, naloxone access is limited—not just by stigma and outdated, restrictive laws, but also by its rising cost. (Filter, USA, 29.0.4.2021)

https://filtermag.org/naloxone-narcan-cost/

Indoor-Cannabisanbau ist schlecht fürs Klima

In den USA wächst die legale Cannabisindustrie. Eine aktuelle Studie zeigt auf: Im Vergleich zur klassischen Landwirtschaft verbraucht der Indoor-Anbau große Mengen Energie und stößt viel des Treibhausgases Kohlendioxid aus. (drugcom.de, 28.04.2021)

https://www.drugcom.de/news/indoor-cannabisanbau-ist-schlecht-fuers-klima/

Leveraging Open Science to Accelerate Research. 

Kadakia KT, Beckman AL, Ross JS, Krumholz HM. 

N Engl J Med. 2021 Apr 29;384(17):e61. doi: 10.1056/NEJMp2034518. Epub 2021 Mar 24. PMID: 33761227.

https://www.nejm.org/doi/full/10.1056/NEJMp2034518

A guide to Plan S: the open-access initiative shaking up science publishing

The push to remove journal paywalls officially started this year. Here’s how it works. (Nature News Explainer, USA, 08.04.2021)

https://www.nature.com/articles/d41586-021-00883-6

USA. UCSF and Johns Hopkins University Launch Digital Trove of Opioid Industry Documents

UC San Francisco and Johns Hopkins University today announced the launch of the Opioid Industry Documents Archive, a digital repository of publicly disclosed documents from recent judgments, settlements, and ongoing lawsuits concerning the opioid crisis. (UC San Francisco, USA, 24.03.2021)

https://www.ucsf.edu/news/2021/03/420136/ucsf-and-johns-hopkins-university-launch-digital-trove-opioid-industry

USA. Opioidkrise: McKinsey zahlt 45 Millionen Dollar

Carson City – McKinsey hat wegen der Beratung von Pharmaunternehmen bei der Vermarktung süchtig machender Schmerzmittel einen weiteren teuren Vergleich akzeptiert. Die Unternehmensberatung zahle zur Beilegung eines Verfahrens wegen dubioser Geschäftspraktiken im US-Bundesstaat Nevada 45 Millionen Dollar (37,7 Millionen Euro), teilte der dortige Generalstaatsanwalt Aaron Ford gestern mit. (aerzteblatt.de, 23.03.2021)

https://www.aerzteblatt.de/nachrichten/122294/Opioidkrise-McKinsey-zahlt-45-Millionen-Dollar

Dschibuti. Khat in Djibouti Drug Trade Is Firmly in Women's Hands in this African Country 

Little functions in the Horn of Africa without the drug khat, and trade in the popular, amphetamine-laden leaf is proving to be crisis-proof. Khat sellers have risen to become their family’s main breadwinners. (Spiegel international online, 18.03.2021)

https://www.spiegel.de/international/world/khat-in-djibouti-drug-trade-is-firmly-in-women-s-hands-in-this-african-country-a-40251ad8-9f3f-4fd5-99ea-59fc0d121989

USA. Purdue Pharma unveils $10bn opioid settlement plan to exit from bankruptcy

Plan is backed by $4bn from Sackler family

Most parties onboard but Democratic attorneys general oppose (The Guardian, UK, 16.03.2021)

https://www.theguardian.com/us-news/2021/mar/16/purdue-pharma-10bn-opioid-settlement-plan-bankruptcy-sackler-family

USA. Pharma-Dynastie Sackler: Der Drogen-Clan 

Amerikas Opioid-Epidemie ist ungebrochen. Hauptursache ist das populäre Schmerzmittel Oxycontin. Jetzt ist die prominente US-Milliardärsfamilie Sackler, die es herstellen lässt, erstmals angeklagt. (Spiegel online, 18.02.2019)

https://www.spiegel.de/wirtschaft/drogenkrise-in-den-usa-us-familie-sackler-angeklagt-a-1253764.html

Mundipharma (Wikipedia)

Die Mundipharma GmbH ist ein mittelständisches forschendes Pharmazieunternehmen mit Sitz in Frankfurt am Main. (…) Das Unternehmen wurde 1967 in Frankfurt am Main von den Brüdern Raymond und Mortimer Sackler, den damaligen Eigentümern von Purdue Pharma, gegründet. (Wikipedia, zuletzt bearbeitet am 17.02.2021)

https://de.wikipedia.org/wiki/Mundipharma

USA. Reckitt Benckiser zahlt 700 Millionen Dollar in Opioid-Vergleich

New York – Der britische Konsumgüterkonzern Reckitt Benckiser hat sich im Streit mit US-Bundesstaaten um dubiose Marketingmethoden für ein opioidhaltiges Medikament auf einen Vergleich geeinigt. (aerzteblatt.de, 24.10.2019)

https://www.aerzteblatt.de/nachrichten/106924/Reckitt-Benckiser-zahlt-700-Millionen-Dollar-in-Opioid-Vergleich

USA. Opioidkrise in den USA: Purdue Pharma bietet mehr als zehn Milliarden Dollar für Vergleich 

Purdue gilt als Hauptverursacher der US-Opioidkrise mit Hunderttausenden Toten. Der Konzern und die Eigentümerfamilie Sackler wollen Tausende Klagen mit einem Vergleich beilegen – und haben nun nachgebessert. (Spiegel online, 16.03.2021)

https://www.spiegel.de/wirtschaft/unternehmen/purdue-pharma-bietet-mehr-als-zehn-milliarden-dollar-fuer-ocycontin-vergleich-a-6b3d0c9b-ff5a-41a6-9254-268348ae02ba

USA. Purdue Pharma Offers Plan to End Sackler Control and Mounting Lawsuits

The OxyContin maker filed its long-awaited restructuring plan in bankruptcy court. Revenue from the new company would go exclusively to abating the opioid crisis. (New York Times, USA, 16.03.2021)

https://www.nytimes.com/2021/03/16/health/purdue-sacklers-bankruptcy-opioids.html

STADA steigt in den Cannabismarkt ein – Mehr Akzeptanz für „Therapie, die noch immer stigmatisiert ist“

Eins der größten deutschen Pharmaunternehmen lanciert seine ersten Cannabisprodukte. Noch sei es ein Nischenmarkt, doch Stada geht von einem großen Wachstumspotenzial aus. (Stada,05.03.2021)

https://www.stada.de/news/detailansicht/handelsblatt-stada-steigt-in-den-cannabismarkt-ein-mehr-akzeptanz-fuer-therapie-die-noch-immer-stigmatisiert-ist.html

UK/USA. BAT buys £126m stake in Canadian cannabis firm OrganiGram

Big tobacco makes further forays into cannabis industry with stake close to 20% in US-listed company. (The Guardian, UK, 11.03.2021)

https://www.theguardian.com/business/2021/mar/11/bat-buys-pounds-126m-stake-canadian-cannabis-firm-organigram-tobacco

USA. Colorado's legal cannabis farms emit more carbon than its coal mines

Legal cannabis production in Colorado alone emits more greenhouse gases than does the state’s coal-mining industry. The energy required to yield one kilogram of dried flower from cannabis grown indoors generates the equivalent of 2–5 tonnes of CO2, depending on where the plant is grown. Most US cannabis is grown indoors under artificial lights, either for legal reasons or to avoid theft. “The profit margins are so huge that you don’t have to be making super energy-conscious decisions,” says Jason Quinn, who analysed the carbon footprint of the emerging US cannabis industry. (New Scientist, UK,08.03.2021)

https://www.newscientist.com/article/2270366-colorados-legal-cannabis-farms-emit-more-carbon-than-its-coal-mines

West-Afrika. British American Tobacco Fights Dirty In West Africa

Billions of cigarettes, most made by BAT, are smuggled north through Mali every year on their way to the gray markets of the Sahel and Northern Africa. (occrp.org - Organized Crime and Corruption Reporting Project, 26.02.2021)

https://www.occrp.org/en/loosetobacco/british-american-tobacco-fights-dirty-in-west-africa

Medizinalcannabis in Deutschland: Übersicht in Zahlen — Branchenverband Cannabiswirtscha: e.V.

ELEMENTE - Materialien zur Cannabiswirtscha: Schri:enreihe des Branchenverband Cannabiswirtscha: e.V. (BvCW), Band 8, 22.02.2021)

https://start.cannabiswirtschaft.de/wp-content/uploads/2021/02/ELEMENTE8_V1_BvCW_Medizinalcannabis_Zahlen.pdf

Deals. Jazz Pharma to Buy Cannabinoid-Drug Maker for $7.2 Billion

Terms represent 50% premium for U.K.-based GW Pharmaceuticals. GW’s Epidiolex was first cannabis-derived drug cleared by FDA. (Bloomberg, USA, 03.02.2021)

https://www.bloomberg.com/news/articles/2021-02-03/jazz-pharmaceuticals-to-buy-gw-for-7-2-billion-in-cash-stock

USA. McKinsey Settles for $573 Million Over Role in Opioid Crisis

The consulting firm has reached the agreement with 47 states because of its advice to drugmakers, including Purdue Pharma, the manufacturer of OxyContin. (New York Times, USA, 03.02.2021)

https://www.nytimes.com/2021/02/03/business/mckinsey-opioids-settlement.html

Deutsche Forschungsgemeinschaft setzt auf Open-Access

Bonn – Die Deutsche Forschungsgemeinschaft (DFG) setzt sich intensiver für das Open-Access in der Wissenschaft ein, also für den freien Zugang zu Publikationen und anderen Forschungsergebnissen im Netz. (aerzteblatt.de, 26.01.2021)

https://www.aerzteblatt.de/nachrichten/120472/Deutsche-Forschungsgemeinschaft-setzt-auf-Open-Access