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Prenatal opioid-exposed infant extracellular miRNA signature obtained at birth predicts severity of neonatal opioid withdrawal syndrome. 

Mahnke AH, Roberts MH, Leeman L, Ma X, Bakhireva LN, Miranda RC. 

Sci Rep. 2022 Apr 8;12(1):5941. doi: 10.1038/s41598-022-09793-7. PMID: 35396369; PMCID: PMC8993911.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993911/

Improving Outcomes through a Neonatal Abstinence Syndrome Collaborative in Maryland. 

DiPietro B, Silcox K, Rost J, Woods L, Edwards EM, Buus-Frank M, Horbar J, Hudak M. 

Am J Perinatol. 2022 Apr 5. doi: 10.1055/a-1817-5522. Epub ahead of print. PMID: 35381608.

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1817-5522

Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis. 

Haan, E, Westmoreland, KE, Schellhas, L, Sallis, HM, Taylor, G, Zuccolo, L, et al. 

Addiction. 2022; 1– 12. doi.org/10.1111/add.15858

https://onlinelibrary.wiley.com/doi/full/10.1111/add.15858

Neonatal Abstinence Syndrome in North Carolina: Incidence and Characteristics among Infants and Mothers. 

Harward ML, Clontz AA, Vo TT, Jiroutek MR, Carter CA. 

N C Med J. 2022 Mar-Apr;83(2):142-146. doi: 10.18043/ncm.83.2.142. PMID: 35256478.

https://www.ncmedicaljournal.com/content/83/2/142.long

Individual and Combined Association Between Prenatal Polysubstance Exposure and Childhood Risk of Attention-Deficit/Hyperactivity Disorder. 

Garrison-Desany HM, Hong X, Maher BS, Beaty TH, Wang G, Pearson C, Liang L, Wang X, Ladd-Acosta C. 

JAMA Netw Open. 2022 Mar 1;5(3):e221957. doi: 10.1001/jamanetworkopen.2022.1957. PMID: 35275164; PMCID: PMC8917426.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917426/

The impact of opioid exposure during pregnancy on the human neonatal immune profile. 

Miller NW, Seman BG, Akers SM, Povroznik JM, Brundage K, Fang W, Robinson CM. The 

Pediatr Res. 2022 Mar 14:1–9. doi: 10.1038/s41390-022-02014-x. Epub ahead of print. PMID: 35288639; PMCID: PMC8920062.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920062/

Use of Phenobarbital to Treat Neonatal Abstinence Syndrome From Exposure to Single vs. Multiple Substances. 

Kushnir A, Garretson C, Mariappan M, Stahl G. 

Front Pediatr. 2022 Jan 31;9:752854. doi: 10.3389/fped.2021.752854. PMID: 35174112; PMCID: PMC8841756.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841756/

Determination of Prenatal Substance Exposure Using Meconium and Orbitrap Mass Spectrometry. 

Hernandez A, Lacroze V, Doudka N, Becam J, Pourriere-Fabiani C, Lacarelle B, Solas C, Fabresse N. 

Toxics. 2022 Jan 26;10(2):55. doi: 10.3390/toxics10020055. PMID: 35202242; PMCID: PMC8875502.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875502/

Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments. 

Tang F, Ng CM, Bada HS, Leggas M. 

Clin Transl Sci. 2021 Jul;14(4):1231-1249. doi: 10.1111/cts.12994. Epub 2021 May 1. PMID: 33650314; PMCID: PMC8301571.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301571/

Aberrant Feeding and Growth in Neonates With Prenatal Opioid Exposure: Evidence of Neuromodulation and Behavioral Changes. 

Yen E, Maron JL. 

Front Pediatr. 2022 Jan 21;9:805763. doi: 10.3389/fped.2021.805763. PMID: 35127598; PMCID: PMC8814597.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814597/

Gestational Age Alters Assessment of Neonatal Abstinence Syndrome. 

Amiri S, Nair J. 

Pediatr Rep. 2022 Jan 28;14(1):50-57. doi: 10.3390/pediatric14010009. PMID: 35225878; PMCID: PMC8883891.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883891/

Comparison of Two Morphine Dosing Strategies in the Management of Neonatal Abstinence Syndrome. 

Harris JB, Holmes AP. 

J Pediatr Pharmacol Ther. 2022;27(2):151-156. doi: 10.5863/1551-6776-27.2.151. Epub 2022 Feb 9. PMID: 35241987; PMCID: PMC8837209.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837209/

Implementation of Interprofessional Rounds Decreases Neonatal Abstinence Syndrome Length of Stay. 

McCarty T, Braswell E. 

J Pediatr Pharmacol Ther. 2022;27(2):157-163. doi: 10.5863/1551-6776-27.2.157. Epub 2022 Feb 9. PMID: 35241988; PMCID: PMC8837217.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837217/

Incidence of Neonatal Abstinence Syndrome (NAS) in Castilla y Leon (Spain). 

Moreno-Ramos M, Sánchez-Barba M, Sánchez RG, Mirón-Canelo JA, González-Nuñez V. 

Children (Basel). 2021 Dec 30;9(1):25. doi: 10.3390/children9010025. PMID: 35053650; PMCID: PMC8774299.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774299/

Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects. 

Cestonaro C, Menozzi L, Terranova C. 

Children (Basel). 2022 Jan 5;9(1):67. doi: 10.3390/children9010067. PMID: 35053692; PMCID: PMC8774427.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774427/

Effects of Prenatal Methamphetamine Exposure on Birth Outcomes, Brain Structure, and Neurodevelopmental Outcomes. 

Zhang Y, Gong F, Liu P, He Y, Wang H. 

Dev Neurosci. 2021;43(5):271-280. doi: 10.1159/000517753. Epub 2021 Jun 17. PMID: 34139695.

https://www.karger.com/Article/FullText/517753

Birth Outcomes of Neonates Exposed to Marijuana in Utero: A Systematic Review and Meta-analysis. 

Marchand G, Masoud AT, Govindan M, et al. 

JAMA Netw Open. 2022;5(1):e2145653. doi:10.1001/jamanetworkopen.2021.45653

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788451

Neonatal Opioid Withdrawal Syndrome (NOWS): A Transgenerational Echo of the Opioid Crisis. 

Weller AE, Crist RC, Reiner BC, Doyle GA, Berrettini WH. 

Cold Spring Harb Perspect Med. 2021 Mar 1;11(3):a039669. doi: 10.1101/cshperspect.a039669. PMID: 32229609; PMCID: PMC7919394.

http://europepmc.org/article/MED/32229609

Characterization of neonatal opioid withdrawal syndrome in Arizona from 2010-2017. 

Eaves ER, Barber J, Whealy R, Clancey SA, Wright R, Cocking JH, Spadafino J, Hepp CM. 

PLoS One. 2021 Jun 3;16(6):e0248476. doi: 10.1371/journal.pone.0248476. PMID: 34081702; PMCID: PMC8174702.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174702/

Neonatal Outcomes after Combined Opioid and Nicotine Exposure in Utero: A Scoping Review. 

Isaacs KR, Atreyapurapu S, Alyusuf AH, Ledgerwood DM, Finnegan LP, Chang KHK, Ma TX, Washio Y. 

Int J Environ Res Public Health. 2021 Sep 28;18(19):10215. doi: 10.3390/ijerph181910215. PMID: 34639512; PMCID: PMC8508043.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508043/

Informing the Development of a Standardized Clinical Definition of Neonatal Abstinence Syndrome: Protocol for a Modified-Delphi Expert Panel. 

Khodyakov D, Jilani SM, Dellva S, Faherty LJ. 

JMIR Res Protoc. 2021 Sep 7;10(9):e25387. doi: 10.2196/25387. PMID: 34491203.

https://www.researchprotocols.org/2021/9/e25387/

Increasing usage of mother’s own milk in neonates at risk of neonatal abstinence syndrome: MOM-NAS quality improvement initiative. 

Shukla, S., Hanna, I., Cortez, J. et al.

J Perinatol (2021). doi.org/10.1038/s41372-021-01209-0

Abstract

https://pubmed.ncbi.nlm.nih.gov/34531531/

Neonatal opioid withdrawal syndrome: a review of the science and a look toward the use of buprenorphine for affected infants.

Devlin LA, Young LW, Kraft WK, Wachman EM, Czynski A, Merhar SL, Winhusen T, Jones HE, Poindexter BB, Wakschlag LS, Salisbury AL, Matthews AG, Davis JM. 

J Perinatol. 2021 Sep 23:1–7. doi: 10.1038/s41372-021-01206-3. Epub ahead of print. PMID: 34556799; PMCID: PMC8459143.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459143/

Improving Hospital Care of Opioid-Exposed Newborns: Successes and Remaining Questions. 

Goyal NK, Kair LR. 

Hosp Pediatr. 2020 Sep;10(9):823-825. doi: 10.1542/hpeds.2020-001149. Epub 2020 Aug 7. PMID: 32769085; PMCID: PMC7446543.

https://hosppeds.aappublications.org/content/10/9/823.long

Improving the Assessment of Neonatal Abstinence Syndrome (NAS). 

Chin Foo CA, Dansereau LM, Hawes K, Oliveira EL, Lester BM. 

Children (Basel). 2021 Aug 9;8(8):685. doi: 10.3390/children8080685. PMID: 34438576; PMCID: PMC8394483.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394483/

Neonatal Abstinence Syndrome Practices in the United States. 

Byerley EM, Mohamed MW, Grindeland CJ, Muzzy Williamson JD. 

J Pediatr Pharmacol Ther. 2021;26(6):577-583. doi: 10.5863/1551-6776-26.6.577. Epub 2021 Aug 16. PMID: 34421406; PMCID: PMC8372852.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372852/

Predictors of Length of Stay and Cost of Hospitalization of Neonatal Abstinence Syndrome in the United States. 

Bhatt P, Umscheid J, Parmar N, Vasudeva R, Patel KG, Ameley A, Donda K, Policano B, Dapaah-Siakwan F. 

Cureus. 2021 Jul 7;13(7):e16248. doi: 10.7759/cureus.16248. PMID: 34373810; PMCID: PMC8346607.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346607/

Effect of Low Lactose Formula on the Short-Term Outcomes of Neonatal Abstinence Syndrome: A Systematic Review. 

Alsaleem M, Dusin J, Akangire G. 

Glob Pediatr Health. 2021 Jul 22;8:2333794X211035258. doi: 10.1177/2333794X211035258. PMID: 34368403; PMCID: PMC8312188.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312188/

Dextromethorphan Dampens Neonatal Astrocyte Activation and Endoplasmic Reticulum Stress Induced by Prenatal Exposure to Buprenorphine. 

Lin CH, Tao PL, Tsay HJ, Chiang YC, Chang WT, Ho IK, Shie FS. 

Behav Neurol. 2021 Jul 10;2021:6301458. doi: 10.1155/2021/6301458. PMID: 34336001; PMCID: PMC8289573.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289573/

Ear Acupuncture Points in Neonates From Drug-Dependent Mothers: A Prospective Study. 

Stähler van Amerongen K, Kuhn A, Surbek D, Nelle M. 

Front Pediatr. 2021 Jun 17;9:668248. doi: 10.3389/fped.2021.668248. PMID: 34222143; PMCID: PMC8247637.

https://www.frontiersin.org/articles/10.3389/fped.2021.668248/full