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Methadone versus morphine treatment outcomes in neonatal abstinence syndrome: A meta-analysis.

Xiao F, Yan K, Zhou W.

J Paediatr Child Health. 2019 Sep 3. doi: 10.1111/jpc.14609.



State Strategies to Address Opioid Use Disorder Among Pregnant and Postpartum Women and Infants Prenatally Exposed to Substances, Including Infants with Neonatal Abstinence Syndrome.

Kroelinger CD, Rice ME, Cox S, et al. 

MMWR Morb Mortal Wkly Rep 2019;68:777–783. DOI: doi.org/10.15585/mmwr.mm6836a1



Ernst KD, Makkar A.

J Okla State Med Assoc. 2018 Oct;111(8):768-774. PMID: 31354174


Successful Implementation of the Eat Sleep Console Model of Care for Infants With NAS in a Community Hospital.

Dodds D, Koch K, Buitrago-Mogollon T, Horstmann S.

Hosp Pediatr. 2019 Aug;9(8):632-638. doi: 10.1542/hpeds.2019-0086. 



Postpartum Nurses' Experience Caring for Infants With Neonatal Abstinence Syndrome.

Loyal J, Nguyen VN, Picagli D, Petrucelli A, O'Mara E, Grossman MR, Colson E.

Hosp Pediatr. 2019 Aug;9(8):601-607. doi: 10.1542/hpeds.2019-0087.



Maternal prepregnancy surgery and risk of neonatal abstinence syndrome in future newborns: a longitudinal cohort study.

Auger N, Low N, Carrier FM, Ayoub A, Luu TM.

CMAJ. 2019 Jul 15;191(28):E779-E786. doi: 10.1503/cmaj.181519.


Neonatal Abstinence Syndrome and Associated Neonatal and Maternal Mortality and Morbidity.

Lisonkova S, Richter LL, Ting J, Muraca GM, Wen Q, Mehrabadi A, Mitchell-Foster S, Oviedo-Joekes E, Lyons J.

Pediatrics. 2019 Aug;144(2). pii: e20183664. doi: 10.1542/peds.2018-3664. 



Cognitive and Motor Outcomes of Children With Prenatal Opioid Exposure: A Systematic Review and Meta-analysis.

Yeoh SL, Eastwood J, Wright IM, Morton R, Melhuish E, Ward M, Oei JL.

JAMA Netw Open. 2019 Jul 3;2(7):e197025. doi: 10.1001/jamanetworkopen.2019.7025.


Reduction in Length of Stay and Morphine Use for NAS With the "Eat, Sleep, Console" Method.

Blount T, Painter A, Freeman E, Grossman M, Sutton AG.

Hosp Pediatr. 2019 Aug;9(8):615-623. doi: 10.1542/hpeds.2018-0238. 



Novel case of maternal and neonatal kratom dependence and withdrawal.

Mackay L, Abrahams R.

Can Fam Physician. 2018 Feb;64(2):121-122.


Comparative effectiveness of opioid replacement agents for neonatal opioid withdrawal syndrome: a systematic review and meta-analysis.

Lee JJ, Chen J, Eisler L, Li G, Davis JM, Sun LS.

J Perinatol. 2019 Jul 17. doi: 10.1038/s41372-019-0437-3. 


Opioids Affect the Fetal Brain: Reframing the Detoxification Debate.

Caritis SN, Panigrahy A.

Am J Obstet Gynecol. 2019 Jul 16. pii: S0002-9378(19)30906-8. doi: 10.1016/j.ajog.2019.07.022.



Low-dose versus high-dose methadone for the management of neonatal abstinence syndrome.

Miller JL, Ernst K, Neely SB, Stephens K, Barker P, Skrepnek GH, Johnson PN.

J Opioid Manag. 2019 Mar/Apr;15(2):159-167. doi: 10.5055/jom.2019.049



Maternal prepregnancy surgery and risk of neonatal abstinence syndrome in future newborns: a longitudinal cohort study

Nathalie Auger, Nancy Low, François M. Carrier, Aimina Ayoub, Thuy Mai Luu

CMAJ Jul 2019, 191 (28) E779-E786; DOI: 10.1503/cmaj.181519 


USA/Kanada. Opiatepidemie steigert Zahl der neonatalen Abstinenzsyndrome in Nordamerika

Montreal – Die großzügige Verschreibung von Opioiden zur postoperativen Schmerzbehandlung gilt als wichtige Ursache der derzeitigen Opioidepidemie in Nordamerika. Eine Folge ist laut einer Studie im Canadian Medical Association Journal (2019; doi: 10.1503/cmaj.181519) eine Zunahme von Geburten mit einem neonatalen Abstinenzsyndrom. (aerzteblatt.de, 16.07.2019)


Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months.

Chau CMY, Ross CJD, Chau V, Synnes AR, Miller SP, Carleton B, Grunau RE.

EBioMedicine. 2019 Feb;40:655-662. doi: 10.1016/j.ebiom.2019.01.042.


Treating women with opioid use disorder during pregnancy in Appalachia: Initial neonatal outcomes following buprenorphine + naloxone exposure.

Nguyen L, Lander LR, O'Grady KE, Marshalek PJ, Schmidt A, Kelly AK, Jones HE.

Am J Addict. 2018 Mar;27(2):92-96. doi: 10.1111/ajad.12687. 


Impact of prenatal exposure to benzodiazepines and z-hypnotics on behavioral problems at 5 years of age: A study from the Norwegian Mother and Child Cohort Study.

Sundbakk LM, Wood M, Gran JM, Nordeng H (2019) 

PLoS ONE 14(6): e0217830. doi.org/10.1371/journal.pone.0217830


Parent's experiences of their child's withdrawal syndrome: a driver for reciprocal nurse-parent partnership in withdrawal assessment.

Craske J, Carter B, Jarman I, Tume L.

Intensive Crit Care Nurs. 2019 Feb;50:71-78. doi: 10.1016/j.iccn.2018.09.001.


Therapeutic approaches for neonatal abstinence syndrome: a systematic review of randomized clinical trials.

Ghazanfarpour M, Najafi MN, Roozbeh N, Mashhadi ME, Keramat-Roudi A, Mégarbane B, Tsatsakis A, Moghaddam MMM, Rezaee R.

Daru. 2019 May 15. doi: 10.1007/s40199-019-00266-3. 


In utero exposure to norbuprenorphine, a major metabolite of buprenorphine, induces fetal opioid dependence and leads to neonatal opioid withdrawal syndrome.

Griffin BA, Caperton CO, Russell LN, Cabalong CV, Wilson CD, Urquhart KR, Martins BS, Zita MD, Patton AL, Alund AW, Owens SM, Fantegrossi WE, Moran JH, Brents LK.

J Pharmacol Exp Ther. 2019 Apr 26. pii: jpet.118.254219. doi: 10.1124/jpet.118.254219.


EEG Findings in Infants With Neonatal Abstinence Syndrome Presenting With Clinical Seizures.

Palla MR, Khan G, Haghighat ZM, Bada H.

Front Pediatr. 2019 Mar 29;7:111. doi: 10.3389/fped.2019.00111. 


Maternal breast milk feeding and length of treatment in infants with neonatal abstinence syndrome.

Favara MT, Carola D, Jensen E, Cook A, Genen L, Dysart K, Greenspan JS, Aghai ZH.

J Perinatol. 2019 Apr 15. doi: 10.1038/s41372-019-0374-1. 



Pilot Study Comparing Modified Finnegan Scoring Versus Adjusted Scoring System for Infants With Iatrogenic Opioid Abstinence Syndrome After Cardiothoracic Surgery.

Capino AC, Johnson PN, Williams PK, Anderson MP, Bedwell S, Miller JL.

J Pediatr Pharmacol Ther. 2019 Mar-Apr;24(2):148-155. doi: 10.5863/1551-6776-24.2.148.


A Scoping Review of Acupuncture as a Potential Intervention for Neonatal Abstinence Syndrome.

Jackson HJ, Lopez C, Miller S, Engelhardt B.

Med Acupunct. 2019 Apr 1;31(2):69-84. doi: 10.1089/acu.2018.1323. 


Differences in hospital length of stay between neonates exposed to buprenorphine versus methadone in utero: A retrospective chart review.

Fernandez S, Bruni T, Bishop L, Turuba R, Olibris B, Jumah NA.

Paediatr Child Health. 2019 May;24(2):e104-e110. doi: 10.1093/pch/pxy091. 



Managing infants born to mothers who have used opioids during pregnancy 

Canadian Paediatric Society, 28.06.2018


Newborns exposed to opioids need mothers more than NICU, say pediatricians.

Vogel L.

CMAJ. 2018 Jan 29;190(4):E123-E124. doi: 10.1503/cmaj.109-5550. 


Associations between Orofacial Clefting and Neonatal Abstinence Syndrome.

Mullens CL, McCulloch IL, Hardy KM, Mathews RE, Mason AC.

Plast Reconstr Surg Glob Open. 2019 Jan 11;7(1):e2095. doi: 10.1097/GOX.0000000000002095.