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Overdose Education and Naloxone Distribution Within Syringe Service Programs - United States, 2019. 

Lambdin BH, Bluthenthal RN, Wenger LD, et al. 

MMWR Morb Mortal Wkly Rep. 2020;69(33):1117-1121. Published 2020 Aug 21. doi:10.15585/mmwr.mm6933a2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439981/

Pharmacists' attitudes toward dispensing naloxone and medications for opioid use disorder: A scoping review of the literature. 

Muzyk A, Smothers ZPW, Collins K, MacEachern M, Wu LT. 

Subst Abus. 2019;40(4):476-483. doi:10.1080/08897077.2019.1616349

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920531/

31. August Internationaler Tag gegen Überdosierungen

Im Jahr 2019 sind in Deutschland 650 Menschen an einer Überdosierung unter Beteiligung von Opioiden verstorben. Diese schlichte Zahl bedeutet hundertfaches Leid in Familien, bei Freund_innen und Bekannten.

Es gilt festzuhalten, dass diese Todesfälle in vielen Fällen sehr einfach zu vermeiden gewesen wären. Mit dem medikament Naloxon als Nasenspray steht ein sicheres Medikament zur verfügung, dass aber bis heute nicht bei Drogengebraucher_innen angekommen ist. (JES – Junkies, Ehemalige und Substituierte, Bundesverband, 28.08.2020)

https://www.jes-bundesverband.de/2020/08/31-august-internationaler-tag-gegen-ueberdosierungen/

EMCDDA. Take-home naloxone programmes in Europe — overdose prevention

EMCDDA, Lissabon, August 2020

https://www.emcdda.europa.eu/publications/topic-overviews/take-home-naloxone

Overdose Education and Naloxone Distribution Within Syringe Service Programs — United States, 2019. 

Lambdin BH, Bluthenthal RN, Wenger LD, et al. 

MMWR Morb Mortal Wkly Rep 2020;69:1117–1121. DOI: doi.org/10.15585/mmwr.mm6933a2

https://www.cdc.gov/mmwr/volumes/69/wr/mm6933a2.htm

Schottland. Access to take-home naloxone increased through paramedic supply

Ambulance paramedics are to supply to patients at risk of an opiate overdose take-home naloxone as part of a pilot scheme in Glasgow. (SDF – Scottish Drugs Forum, UK, August 2020)

Schottland. Access to take-home naloxone increased through paramedic supply

Protocol for Take-home naloxone In Multicentre Emergency (TIME) settings: feasibility study. 

Jones M, Bell F, Benger J, et al. 

Pilot Feasibility Stud. 2020;6:96. Published 2020 Jul 9. doi:10.1186/s40814-020-00626-w

 

Schottland. National Naloxone programme Scotland 

Monitoring report 2018/19, An Official Statistics publication for Scotland

Published: 11 August 2020 (Latest release)

This release by Public Health Scotland presents information on the number of take-home naloxone kits issued by the National Naloxone Programme in Scotland. Figures are presented separately for kits issued from community outlets, kits issued in prisons at the point of prisoner release and kits dispensed via community prescription.

Schottland. National Naloxone programme Scotland 

Addressing co-occurring public health emergencies: The importance of naloxone distribution in the era of COVID-19 

Collins AB, Ndoye CD, Arene-Morley D, Marshall BDL. 

[published online ahead of print, 2020 Jul 21]. Int J Drug Policy. 2020;102872. doi:10.1016/j.drugpo.2020.102872

Addressing co-occurring public health emergencies: The importance of naloxone distribution in the era of COVID-19 

Layperson reversal of opioid overdose supported by smartphone alert: A prospective observational cohort study

Schwartz, David G. et al.

EClinicalMedicine, Volume 0, Issue 0, 100474 

www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30218-2/fulltext

Legal requirements and recommendations to prescribe naloxone. 

Haffajee RL, Cherney S, Smart R. 

Drug Alcohol Depend. 2020;209:107896. doi:10.1016/j.drugalcdep.2020.107896

Legal requirements and recommendations to prescribe naloxone. 

USA. FDA recommends health care professionals discuss naloxone with all patients when prescribing opioid pain relievers or medicines to treat opioid use disorder 

Consider prescribing naloxone to those at increased risk of opioid overdose.

07-23-2020 FDA Drug Safety Communication.

www.fda.gov/drugs/drug-safety-and-availability/fda-recommends-health-care-professionals-discuss-naloxone-all-patients-when-prescribing-opioid-pain

Bayern. Nasenspray gegen Drogentod: Fast 500 Menschen geschult

München – Fast 500 Menschen sind in Bayern mittlerweile für den Einsatz von lebensret­tendem Nasenspray für Heroinabhängige geschult worden. „In 70 Notfallsituationen kam Naloxon gezielt zum Einsatz und konnte somit Leben retten“, sagte Gesundheitsministerin Melanie Huml (CSU) vorgestern laut Mitteilung. (aerzteblatt.de, 04.08.2020)

Bayern. Nasenspray gegen Drogentod: Fast 500 Menschen geschult

Spectrometric Imaging of the Brain Demonstrates the Regional Displacement of 6-Monoacetylmorphine by Naloxone. 

Teklezgi BG, Pamreddy A, Ntshangase S, et al. Mass 

ACS Omega. 2020;5(22):12596-12602. Published 2020 May 27. doi:10.1021/acsomega.9b03570

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288357/

Higher naloxone dosing in a quantitative systems pharmacology model that predicts naloxone-fentanyl competition at the opioid mu receptor level. 

Moss RB, Pryor MM, Baillie R, Kudrycki K, Friedrich C, Reed M, et al. (2020) 

PLoS ONE 15(6): e0234683. https://doi.org/10.1371/journal.pone.0234683

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234683

Opioid antidote induced pulmonary edema and lung injury. 

Yarlagadda K, Kim J, Kanderi T, Sendil S, Nookala VK. Opioid 

Respir Med Case Rep. 2020;30:101107. Published 2020 May 29. doi:10.1016/j.rmcr.2020.101107

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287275/

Does intranasal naloxone administration increase the risk of 2019 coronavirus disease transmission?

Leong YC, Verbeek PR. 

CJEM. 2020 May 12:1-2. doi: 10.1017/cem.2020.395.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251251/

Regional variation in states' naloxone accessibility laws in association with opioid overdose death rates-Observational study (STROBE compliant). 

You HS, Ha J, Kang CY, et al. 

Medicine (Baltimore). 2020;99(22):e20033. doi:10.1097/MD.0000000000020033

https://journals.lww.com/md-journal/FullText/2020/05290/Regional_variation_in_states__naloxone.18.aspx

Abgabe von Naloxon in Deutschland - Deutscher Bundestag Drucksache 19/18361 19. Wahlperiode 24.03.2020 

Antwort der Bundesregierung auf die Kleine Anfrage der Abgeordneten Dr. Wieland Schinnenburg, Michael Theurer, Grigorios Aggelidis, weiterer Abgeordneter und der Fraktion der FDP – Drucksache 19/17670 – 

https://dip21.bundestag.de/dip21/btd/19/183/1918361.pdf

Barriers to and recommendations for take-home naloxone distribution: perspectives from opioid treatment programs in New Mexico.

Salvador, J.G., Sussman, A.L., Takeda, M.Y. et al.

Harm Reduct J 17, 31 (2020). doi.org/10.1186/s12954-020-00375-2

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-020-00375-2

FDA Initiative for Drug Facts Label for Over-the-Counter Naloxone

Cohen BR, Mahoney KM, Baro E, et al. 

N Engl J Med. 2020;382(22):2129‐2136. doi:10.1056/NEJMsa1912403

https://www.nejm.org/doi/full/10.1056/NEJMsa1912403

Intranasal versus Intramuscular/Intravenous Naloxone for Pre-hospital Opioid Overdose: A Systematic Review and Meta-analysis.

Yousefifard M, Vazirizadeh-Mahabadi MH, Neishaboori AM, Alavi SNR, Amiri M, Baratloo A, Saberian P.

Adv J Emerg Med. 2019 Nov 16;4(2):e27. doi: 10.22114/ajem.v0i0.279.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163267/

Safety of Naloxone in Opioid-Naïve Methadone Intoxicated Patients; a Case Series Study.

Shakeri SHR, Hassanian-Moghaddam H, Zamani N.

Arch Acad Emerg Med. 2020 Mar 2;8(1):e16. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130441/

Protocol for a multi-site study of the effects of overdose prevention education with naloxone distribution program in Skåne County, Sweden.

Troberg K, Isendahl P, Blomé MA, Dahlman D, Håkansson A.

BMC Psychiatry. 2020 Feb 7;20(1):49. doi: 10.1186/s12888-020-2470-3.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006080/

Administration of Naloxone in a Home or Community Setting: A Review of the Clinical Effectiveness, Cost-effectiveness, and Guidelines [Internet].

Chao YS, Loshak H.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Dec 18.

https://www.ncbi.nlm.nih.gov/books/NBK554744/

Administration of Naloxone in a Home or Community Setting: A Review of the Clinical Effectiveness, Cost-effectiveness, and Guidelines [Internet].

Chao YS, Loshak H.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Dec 18.

https://www.ncbi.nlm.nih.gov/books/NBK554744/

Implementation of an Opioid Overdose and Naloxone Distribution Training in a Pharmacist Laboratory Course.

Kwon M, Moody AE, Thigpen J, Gauld A. 

Am J Pharm Educ. 2020 Feb;84(2):7179. doi: 10.5688/ajpe7179.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092781/

The Prescribing and Education of Naloxone in a Large Academic Medical Center.

Miller S, Williams L, Thompson AN.

Pharmacy (Basel). 2020 Mar 5;8(1). pii: E31. doi: 10.3390/pharmacy8010031.

https://www.mdpi.com/2226-4787/8/1/31

Fatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland. 

Buresh M, Gicquelais RE, Astemborski J, Kirk GD, Mehta SH, Genberg BL (2020) 

PLoS ONE 15(3): e0230127. doi.org/10.1371/journal.pone.0230127

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230127

Pharmacological Profile of Naldemedine, a Peripherally Acting μ-Opioid Receptor Antagonist: Comparison with Naloxone and Naloxegol.

Kanemasa T, Koike K, Takase K, Arai T, Nakamura A, Morioka Y, Hasegawa M.

J Pharmacol Exp Ther. 2020 Mar 13. pii: jpet.119.264515. doi: 10.1124/jpet.119.264515. 

http://jpet.aspetjournals.org/content/early/2020/03/13/jpet.119.264515.long