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Thresholds for safer alcohol use might need lowering

Connor, Jason et al.

The Lancet , Volume 391 , Issue 10129 , 1460 - 1461

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30545-2/fulltext

Trends in alcoholrelated mortality in East and West Germany, 1980–2014: age, period and cohort variations.

Piontek, D., and Kraus, L. (2018)

Addiction, 113: 836–844. doi: 10.1111/add.14152.

Abstract

https://onlinelibrary.wiley.com/doi/abs/10.1111/add.14152

The International Model of Alcohol Harms and Policies
The International Model of Alcohol Harms and Policies (InterMAHP) version 1.0 is a comprehensive set of guidelines, methods and manuals, as well as a SAS®-based tool created towards the goal of standardizing and automating the calculation and application of alcohol-attributable fractions (AAFs) globally. 

Our intention is that it will be used by international alcohol research teams to assist in alcohol harms estimation, in particular in relation to alcohol-attributable mortality and morbidity calculation. (University of Victoria, Canadian Institute for Substance Use Research, Dezember 2017)

https://www.uvic.ca/research/centres/cisur/projects/intermahp/index.php/

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

Wood, Angela MWood, Angela M et al.

The Lancet , Volume 391 , Issue 10129 , 1513 - 1523

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30134-X/fulltext

Schon geringe Menge Alkohol steigert Sterberisiko

München/London – Weniger ist besser: Die Richtwerte für den Konsum von Alkohol sind in vielen Ländern einer Untersuchung zufolge zu hoch – auch in Deutschland. Eine große Übersichtsstudie zeigt, dass der Konsum von mehr als 100 Gramm reinem Alkohol pro Woche – das entspricht etwa fünfeinhalb Gläsern Wein oder 2,5 Litern Bier – das Risiko erhöht, zu sterben und Herz-Kreislauf-Erkrankungen zu entwickeln. Das berichtet ein internationales Forscherteam im Lancet (2018; doi: 10.1016/S0140-6736(18)30134-X). (aerzteblatt.de, 13.04.2018)

https://www.aerzteblatt.de/nachrichten/93425/Schon-geringe-Menge-Alkohol-steigert-Sterberisiko

Benzodiazepine maintenance for alcohol dependence: A case series.

Kattimani S, Bharadwaj B, Arun AB.

J Family Med Prim Care. 2017 Apr-Jun;6(2):431-433. doi: 10.4103/2249-4863.220038.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749099/

Warum Alkohol Menschen aggressiver macht

Sydney – Australische Forscher um Thomas Denson von der University of New South Wales haben mittels Magnetresonanztomographien (MRT), die den Blutfluss im Gehirn messen, untersucht, warum Menschen oft aggressiv und gewalttätig werden, nachdem sie Alkohol getrunken haben. Nach nur zwei Drinks stellten die Forscher Veränderungen in der Funktionsweise des präfrontalen Kortex des Gehirns fest, dem Teil, der normalerweise an der Regulierung der Aggressionsniveaus einer Person beteiligt ist. Die Studie ist in der Zeitschrift Cognitive, Affective, & Behavioral Neuroscience erschienen (2018; doi: 10.3758/s13415-017-0558-0). (aerzteblatt.de, 02.03.2018)

https://www.aerzteblatt.de/nachrichten/91554/Warum-Alkohol-Menschen-aggressiver-macht

Alkoholatlas Deutschland 2017

Dr. Katrin Schaller, Dipl.-Biol. Sarah Kahnert, PD Dr. Ute Mo

DKFZ – Deutsches Krebsforschungszentrum, 2017

http://www.dkfz.de/de/tabakkontrolle/download/Publikationen/sonstVeroeffentlichungen/Alkoholatlas-Deutschland-2017_Doppelseiten.pdf

Baclofen: its effectiveness in reducing harmful drinking, craving, and negative mood. A meta-analysis.

Rose, A. K., and Jones, A. (2018)

Addiction, doi: 10.1111/add.14191.

Abstract

http://onlinelibrary.wiley.com/doi/10.1111/add.14191/full

Gabapentin for the treatment of alcohol use disorder.

Mason BJ, Quello S, Shadan F.

Expert Opin Investig Drugs. 2017 Dec 23:1-12. doi: 10.1080/13543784.2018.1417383.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29241365

Nicotine-Use/Smoking Is Associated with the Efficacy of Naltrexone in the Treatment of Alcohol Dependence.

Anton RF, Latham PK, Voronin KE, Randall PK, Book SW, Hoffman M, Schacht JP.

Alcohol Clin Exp Res. 2018 Feb 12. doi: 10.1111/acer.13601.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29431852

Long-term alcohol use patterns and HIV disease severity.

Marshall BDL, Tate JP, McGinnis KA, Bryant KJ, Cook RL, Edelman EJ, Gaither JR, Kahler CW, Operario D, Fiellin DA, Justice AC.

AIDS. 2017 Jun 1;31(9):1313-1321. doi: 10.1097/QAD.0000000000001473.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/28492393

Kanada. Radical harm reduction: coming out from under the radar (managed alcohol programs)

The practice of providing alcohol to people with severe alcohol dependence is a complex and sometimes controversial approach to harm-reduction, and it’s one that many communities in Canada have tried—some very publically and some quietly under the radar. These programs which give alcohol in measured, regular doses throughout the day, usually along with housing and other supports, are known as Managed Alcohol Programs, or MAPs. (University of Victoria, 19.02.2018)

https://www.uvic.ca/news/topics/2018+cisur-managed-alcohol-programs+media-release

Discrimination and drinking: A systematic review of the evidence.

Gilbert PA, Zemore SE.

Soc Sci Med. 2016 Jul;161:178-94. doi: 10.1016/j.socscimed.2016.06.009. Epub 2016 Jun 9. Review.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921286/

What about drinking is associated with shorter life in poorer people?

Rehm J, Probst C (2018)

PLoS Med 15(1): e1002477. doi.org/10.1371/journal.pmed.1002477

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002477

Sustained effectiveness and cost-effectiveness of Counselling for Alcohol Problems, a brief psychological treatment for harmful drinking in men, delivered by lay counsellors in primary care: 12-month follow-up of a randomised controlled trial.

Nadkarni A, Weiss HA, Weobong B, McDaid D, Singla DR, Park A-L, et al. (2017)

PLoS Med 14(9): e1002386. https://doi.org/10.1371/journal.pmed.1002386

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002386

Real-time assessment of alcohol drinking and drug use in opioid-dependent polydrug users.

Preston KL, Jobes ML, Phillips KA, Epstein DH.

Behav Pharmacol. 2016 Oct;27(7):579-84. doi: 10.1097/FBP.0000000000000250.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010032/

Methadonsubstitution: Abhängige steigen zunehmend auf Alkohol um

Zürich – Die Methadonprogramme im Schweizer Kanton Zürich haben sich auch langfristig als erfolgreich erwiesen. Der Anteil der Abhängigen, die zusätzlich Heroin oder Kokain konsumieren, ist laut einer Studie in Lancet Psychiatry (2017; doi:10.1016/S2215-0366(17)30080-9) zurückgegangen. Viele Abhängige haben aber den Alkohol als Ersatz entdeckt. (aerzteblatt.de, 02.03.2017)

https://www.aerzteblatt.de/nachrichten/73419/Methadonsubstitution-Abhaengige-steigen-zunehmend-auf-Alkohol-um

The Impact of Enrolment in Methadone Maintenance Therapy on Initiation of Heavy Drinking among People Who Use Heroin.

Klimas J, Wood E, Nguyen P, Dong H, Milloy MJ, Kerr T, Hayashi K.

Eur Addict Res. 2016;22(4):210-4. doi: 10.1159/000444513.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862898/

Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders: a systematic review with direct and network meta-analyses on nalmefene, naltrexone, acamprosate, baclofen and topiramate

Palpacuer, C., Duprez, R., Huneau, A., Locher, C., Boussageon, R., Laviolle, B., and Naudet, F. (2017).

Addiction, doi: 10.1111/add.13974.

http://onlinelibrary.wiley.com/doi/10.1111/add.13974/full

Hazardous Alcohol Use Associated with Increased Sexual Risk Behaviors Among People Who Inject Drugs.

Fairbairn N, Hayashi K, Milloy MJ, Nolan S, Nguyen P, Wood E, Kerr T.

Alcohol Clin Exp Res. 2016 Nov;40(11):2394-2400. doi: 10.1111/acer.13216.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073007/