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Trends in pregnancy-associated mortality involving opioids in the United States, 2007-2016.

Gemmill A, Kiang MV, Alexander MJ.

Am J Obstet Gynecol. 2018 Sep 28. pii: S0002-9378(18)30820-2. doi: 10.1016/j.ajog.2018.09.028. 

https://www.ajog.org/article/S0002-9378(18)30820-2/fulltext

USA. Healthy Pregnancy Healthy Baby Fact Sheets

This series of four fact sheets emphasizes the importance of continuing a mother's treatment for opioid use disorder (OUD) throughout pregnancy. The series includes information on OUD and pregnancy, OUD treatment, neonatal abstinence syndrome, and considerations to address before hospital discharge. (SAMSHA - Substance Abuse and Mental Health Services Administration, USA, August 2018)

https://store.samhsa.gov/product/Opioid-Use-Disorder-and-Pregnancy/sma18-5071

Cannabis: THC noch nach sechs Tagen in der Brustmilch nachweisbar

San Diego – Die psychoaktive Substanz Tetrahydrocannabinol (THC) war in einer Studie in Pediatrics (2018; doi: 10.1542/peds.2018-1076) bei stillenden Frauen, die Cannabis konsumiert hatten, noch bis zu 6 Tage in der Muttermilch nachweisbar. (aerzteblatt.de, 29.08.2018)

https://www.aerzteblatt.de/nachrichten/97491/Cannabis-THC-noch-nach-sechs-Tagen-in-der-Brustmilch-nachweisbar

Prenatal food insecurity associated with severity of neonatal abstinence syndrome 

A new study shows that food insecurity in pregnant women being treated for opioid use disorder may be associated with increased risk for their infants receiving pharmacologic treatment for neonatal abstinence syndrome. Published in Addiction, the Boston Medical Center study indicates that screening for food insecurity in pregnant women who are being treated with opioid agonist therapy (methadone or buprenorphine) for an opioid use disorder could be one way to decrease the severity of neonatal abstinence syndrome in their infants. (Boston Medical Center, USA, 13.11.2018)

https://www.eurekalert.org/pub_releases/2018-11/bmc-pfi111218.php

Schweiz. Broschüre "Schwangerschaft und Alkohol,Schwangerschaft und Tabak: Gut zu wissen", in 9 Sprachen. Informationen für werdende Mütter, Frauen mit Kinderwunsch, Väter sowie Nahestehende.

Sprachen: Deutsch, Französisch, Italienisch, Albanisch, Englisch, Spanisch, Portugiesisch, Serbisch/Kroatisch/Bosnisch, Türkisch

Sucht Schweiz, Lausanne, 2016

https://shop.addictionsuisse.ch/de/home/627-schwangerschaft-und-alkohol-schwangerschaft-und-tabak-.html

USA. Addiction and Pregnancy (Boston Medical Center Themenseite)  

What is Project RESPECT?

Project RESPECT (Recovery, Empowerment, Social Services, Prenatal care, Education, Community and Treatment), is a high risk obstetrical and addiction recovery medical home at Boston Medical Center and Boston University School of Medicine. Project RESPECT provides a unique service of comprehensive obstetric and substance use disorder treatment for pregnant women and their newborns in Massachusetts.  (Stand November 2018)

https://www.bmc.org/obstetrics/pregnancy/addiction

Drugs and Lactation Database (LactMed) 

What is LactMed?

The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Suggested therapeutic alternatives to those drugs are provided, where appropriate. All data are derived from the scientific literature and fully referenced. A peer review panel reviews the data to assure scientific validity and currency.

Updates: LactMed is updated monthly.

https://toxnet.nlm.nih.gov/newtoxnet/lactmed.htm

Impact of timing of methadone initiation on perinatal outcomes following delivery among pregnant women on methadone maintenance therapy in Ontario.

Guan, Q., Sproule, B. A., Vigod, S. N., Cadarette, S. M., Greaves, S., Martins, D., and Gomes, T. (2018) 

Addiction, doi.org/10.1111/add.14453.

Abstract

https://onlinelibrary.wiley.com/doi/10.1111/add.14453

Treatment modalities for pregnant women with opioid use disorder

Laura E Gressler, Doris Titus-Glover, Fadia Tohme Shaya

The Lancet, Volume 392, ISSUE 10147, P551, August 18, 2018doi.org/10.1016/S0140-6736(18)31471-5

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31471-5/fulltext

Opium use during pregnancy and infant size at birth: a cohort study.

Maghsoudlou S, Cnattingius S, Montgomery S, Aarabi M, Semnani S, Wikström AK, Bahmanyar S.

BMC Pregnancy Childbirth. 2018 Oct 1;18(1):358. doi: 10.1186/s12884-018-1994-8.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166275/

Heroin - Drugs and Lactation Database 

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Last Revision: May 1, 2018.

https://www.ncbi.nlm.nih.gov/books/NBK500783/

Expecting Better - Improving Health and Rights for Pregnant Women Who Use Drugs

Drug use in pregnancy can lead to serious health risks for both the mother and the fetus, including HIV infection and fatal overdose. At the same time, drug use during pregnancy need not lead to any negative outcomes, or to outcomes significantly different from those experienced by non drug-using women. (Open Society Foundations, USA, Oktober 2018)

https://www.opensocietyfoundations.org/sites/default/files/expecting-better-improving-health-and-rights-for-pregnant-women-who-use-drugs-20181016.pdf

Stabilizing the Mother-Infant Dyad for Better Outcomes from OB to FM: Caring for Patients with Perinatal Opioid Use Disorder through the 4th Trimester.

Ramage M, Ostrach B, Fagan B, Coulson CC.

N C Med J. 2018 May-Jun;79(3):164-165. doi: 10.18043/ncm.79.3.164. 

http://www.ncmedicaljournal.com/content/79/3/164.long

Trends and Outcomes Associated With Using Long-Acting Opioids During Delivery Hospitalizations.

Duffy CR, Wright JD, Landau R, Mourad MJ, Siddiq Z, Kern-Goldberger AR, D'Alton ME, Friedman AM.

Obstet Gynecol. 2018 Oct;132(4):937-947. doi: 10.1097/AOG.0000000000002861.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30204694

Methadone - Drugs and Lactation Database.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Last Revision: June 4, 2018.

https://www.ncbi.nlm.nih.gov/books/NBK501233/

Prenatal Treatment and Outcomes of Women With Opioid Use Disorder.

Brogly SB, Saia KE, Werler MM, Regan E, Hernández-Díaz S.

Obstet Gynecol. 2018 Oct;132(4):916-922. doi: 10.1097/AOG.0000000000002881.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30204704

Study analyzes opioid overdose risk during and after pregnancy among Massachusetts women 

Overdose risk drops during pregnancy but rises after delivery, when fewer resources are available to mothers with substance use disorder. (Massachusetts General Hospital, 11.07.2018)

https://www.eurekalert.org/pub_releases/2018-07/mgh-sao071118.php

USA. PERINATAL SUBSTANCE USE - INFOGRAPHICS and SOCIAL MEDIA POSTS

At NPA we know that the language that we use shapes the way we think. We want to change the way we talk about pregnancy and substance use. We encourage you to download, print, and share these with your community. (National Perinatal Asociation, USA)

http://www.nationalperinatal.org/Infographics

Buprenorphine - Drugs and Lactation Database

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Last Revision: June 4, 2018.

https://www.ncbi.nlm.nih.gov/books/NBK501202/

Screening Pregnant Women and Their Neonates for Illicit Drug Use: Consideration of the Integrated Technical, Medical, Ethical, Legal, and Social Issues.

Price HR, Collier AC, Wright TE.

Front Pharmacol. 2018 Aug 28;9:961. doi: 10.3389/fphar.2018.00961. eCollection 2018. Review.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120972/

Psychotic due to bath salts and methamphetamines: emergency cesarean section under general anesthesia.

Nina S.

J Biomed Res. 2018 Jul 2. doi: 10.7555/JBR.32.20180023. 

http://www.jbr-pub.org.cn/uploadfile/JBR-2018-0023.pdf

IRIS: Onlineberatung für Schwangere

Für eine gesunde Beziehung zu Ihrem ungeborenen Kind: Wir helfen Ihnen, mit Alkohol und Zigaretten Schluss zu machen.

Schwangeren ist es ein Anliegen, dass ihr Baby gesund zur Welt kommt und sich gut entwickelt. 

Es gibt viel, was Sie als werdende Mutter dafür tun können. Dazu gehört auch, in der Schwangerschaft nicht zu rauchen und keinen Alkohol zu trinken. Das fällt nicht immer ganz leicht. IRIS unterstützt Siedabei, alkohol- und rauchfrei durch Ihre Schwangerschaft zu gehen. (iris-plattform.de, September 2018

https://www.iris-plattform.de/

Buprenorphine/naloxone in the Treatment of Opiate Dependency during Unintentional Pregnancies - Bosnia-Herzegovina Experiences.

Hasanović M, Pajević I, Kuldija A, Delić A, Hrvić D.

Psychiatr Danub. 2018 Jun;30(2):230-232. 

http://www.hdbp.org/psychiatria_danubina/pdf/dnb_vol30_no2/dnb_vol30_no2_230.pdf

Perinatal Drug Abuse And Neonatal Drug Withdrawal.

Shukla S, Gomez Pomar E.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-.
2018 Jul 27.

https://www.ncbi.nlm.nih.gov/books/NBK519061/

Gestational changes in buprenorphine exposure: A physiologically-based pharmacokinetic analysis.

Zhang H, Kalluri HV, Bastian JR, Chen H, Alshabi A, Caritis SN, Venkataramanan R.

Br J Clin Pharmacol. 2018 Jun 5. doi: 10.1111/bcp.13642.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29873094

Adverse Pregnancy Outcomes Associated With Gestational Exposure to Antiepileptic Drugs.

Andrade C.

J Clin Psychiatry. 2018 Jul 31;79(4). pii: 18f12467. doi: 10.4088/JCP.18f12467.

http://www.psychiatrist.com/JCP/article/Pages/2018/v79/18f12467.aspx

The Pregnancy Recovery Center: A women-centered treatment program for pregnant and postpartum women with opioid use disorder.

Krans EE, Bobby S, England M, Gedekoh RH, Chang JC, Maguire B, Genday P, English DH.

Addict Behav. 2018 May 24. pii: S0306-4603(18)30529-X. doi: 10.1016/j.addbeh.2018.05.016.

Abstract

https://www.sciencedirect.com/science/article/abs/pii/S030646031830529X

Mom's use of opioids in pregnancy may stunt kids' learning

Learning disabilities and other special education needs are common in children born with opioid-related symptoms from their mother's drug use while pregnant, according to the first big U.S. study to examine potential long-term problems in these infants. 

About 1 in 7 affected children required special classroom services for problems including developmental delays and speech or language difficulties, compared with about 1 in 10 children not exposed to opioids before birth, the study found. (MedicalXpress, USA, 30.08.2018)

https://medicalxpress.com/news/2018-08-mom-prenatal-opioids-stunt-kids.html

Does Maternal Buprenorphine Dose Affect Severity or Incidence of Neonatal Abstinence Syndrome?

Wong J, Saver B, Scanlan JM, Gianutsos LP, Bhakta Y, Walsh J, Plawman A, Sapienza D, Rudolf V.

J Addict Med. 2018 Jun 13. doi: 10.1097/ADM.0000000000000427.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29905586

USA. AAP Raises Concerns About Increasing Marijuana Use During Pregnancy and Breastfeeding

Itasca, IL - With marijuana use more commonly reported by women who are pregnant or breastfeeding, a new American Academy of Pediatrics (AAP) report calls for more research on possible developmental effects on children. Highlighting emerging evidence that marijuana likely is not harmless as widely assumed, the AAP recommends women avoid the drug while pregnant or nursing a child. (American Academy of Pediatrics, 27.08.2018)

https://www.aap.org/en-us/about-the-aap/aap-press-room/Pages/AAP-Raises-Concerns-About-Increasing-Marijuana-Use-During-Pregnancy-and-Breastfeeding.aspx