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Changing Outdated Methadone Regulations That Harm Pregnant Patients 

McCarthy JJ, Jones HE, Terplan M, Rudolf VP, von Klimo MC. 

[published online ahead of print, 2020 Aug 18]. J Addict Med. 2020;10.1097/ADM.0000000000000720. doi:10.1097/ADM.0000000000000720

Abstract

https://pubmed.ncbi.nlm.nih.gov/32826620/

Association of Pregnancy and Insurance Status With Treatment Access for Opioid Use Disorder. 

Patrick SW, Richards MR, Dupont WD, et al. 

JAMA Netw Open. 2020;3(8):e2013456. Published 2020 Aug 3. doi:10.1001/jamanetworkopen.2020.13456

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428808/

Associations of Maternal Prenatal Drug Abuse With Measures of Newborn Brain Structure, Tissue Organization, and Metabolite Concentrations 

Peterson BS, Rosen T, Dingman S, et al. 

[published online ahead of print, 2020 Jun 15]. JAMA Pediatr. 2020;e201622. 

https://jamanetwork.com/journals/jamapediatrics/article-abstract/2766728

Opioid use disorder in pregnancy

Anshula Ambasta and Mary Malebranche

CMAJ September 23, 2019 191 (38) E1057; DOI: doi.org/10.1503/cmaj.190391 

https://www.cmaj.ca/content/191/38/E1057.long

Medications for opioid use disorder among pregnant women referred by criminal justice agencies before and after Medicaid expansion: A retrospective study of admissions to treatment centers in the United States.

Winkelman TNA, Ford BR, Shlafer RJ, McWilliams A, Admon LK, Patrick SW (2020) 

PLoS Med 17(5): e1003119. doi.org/10.1371/journal.pmed.1003119

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003119

DAH. "DU LIEBES KIND" - Drogengebrauch und Schwangerschaft

Die DAH hat ein neues Medium mit Dr Siedentopf und Frau Nagel von der Charite veröffentlicht. "DU LIEBES KIND", Es geht um Drogengebrauch und Schwangerschaft und gibt Antworten auf viele Fragen rund um das Thema Schwangerschaft gibt, beispielsweise: Darf eine Drogenabhängige überhaupt Kinder bekommen? Können Drogen dem Kind schaden? Drogen und Mutterschaft? Muss die Lebensführung geändert werden? - Mit Adressen von Beratungsstellen.

Frauen die Drogen gebrauchen werden mit Informationen versorgt, die sie durch die Zeit vor, während und nach ihrer Schwangerschaft begleiten. Dazu gibt es Checklisten und das Thema Substitution spielt eine Rolle. (DAH – Deutsche AIDS-Hilfe, Broschüre, vollständig überarbeitete Auflage im neuen Design, 56 Seiten, 2020)

https://www.aidshilfe.de/shop/liebes-kind

Breastfeeding Intention Compared With Breastfeeding Postpartum Among Women Receiving Medication-Assisted Treatment.

Yonke N, Maston R, Weitzen S, Leeman L.

J Hum Lact. 2019 Feb;35(1):71-79. doi: 10.1177/0890334418769637. 

Abstract

https://journals.sagepub.com/doi/abs/10.1177/0890334418769637

Alcohol and Psychoactive Drugs in Pregnancy.

Hetea A, Cosconel C, Stanescu AAM, Simionescu AA.

Maedica (Buchar). 2019 Dec;14(4):397-401. doi: 10.26574/maedica.2019.14.4.397.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035437/

Potential effects of using non-combustible tobacco and nicotine products during pregnancy: a systematic review.

Glover, M., Phillips, C.V. 

Harm Reduct J 17, 16 (2020). doi.org/10.1186/s12954-020-00359-2

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-020-00359-2

Treatment of Opioid Use Disorder in Pregnant Women via Telemedicine: A Nonrandomized Controlled Trial.

Guille C, Simpson AN, Douglas E, Boyars L, Cristaldi K, McElligott J, Johnson D, Brady K.

JAMA Netw Open. 2020 Jan 3;3(1):e1920177. doi: 10.1001/jamanetworkopen.2019.20177.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2759839

Maternal prescribed opioid analgesic use during pregnancy and associations with adverse birth outcomes: A population-based study.

Sujan AC, Quinn PD, Rickert ME, Wiggs KK, Lichtenstein P, Larsson H, et al. (2019) 

PLoS Med 16(12): e1002980. doi.org/10.1371/journal.pmed.1002980

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002980

Opioid use disorder in pregnancy.

Harter K.

Ment Health Clin. 2019 Nov 27;9(6):359-372. doi: 10.9740/mhc.2019.11.359.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881108/

Antepartum Drug Dependence and Pregnancy- or Birth-related Complications: A Cross-sectional Study of 19 Million Inpatients.

Ahmad N, Robert CA, Jampa A, Ashraf S, Patel RS.

Cureus. 2019 Nov 10;11(11):e6117. doi: 10.7759/cureus.6117.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903893/

Naltrexone use in pregnancy: a time for change.

Caritis SN, Venkataramanan R.

Am J Obstet Gynecol. 2020 Jan;222(1):1-2. doi: 10.1016/j.ajog.2019.08.041. 

https://doi.org/10.1016/j.ajog.2019.08.041

Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.

Korchynska S, Krassnitzer M, Malenczyk K, Prasad RB, Tretiakov EO, Rehman S, Cinquina V, Gernedl V, Farlik M, Petersen J, Hannes S, Schachenhofer J, Reisinger SN, Zambon A, Asplund O, Artner I, Keimpema E, Lubec G, Mulder J, Bock C, Pollak DD, Romanov RA, Pifl C, Groop L, Hökfelt TG, Harkany T.

EMBO J. 2019 Nov 21:e100882. doi: 10.15252/embj.2018100882.

https://www.embopress.org/doi/full/10.15252/embj.2018100882

Preventing the Use of Marijuana: Focus on Women and Pregnancy

This guide supports health care providers, systems, and communities seeking to prevent marijuana use among pregnant women. It describes relevant research findings, examines emerging and best practices, identifies knowledge gaps and implementation challenges, and offers useful resources. (SAMHSA - Substance Abuse and Mental Health Services Administration, USA, Dezember 2019)

https://store.samhsa.gov/system/files/pep19-pl-guide-2.pdf

Buprenorphine and Naloxone Versus Buprenorphine for Opioid Use Disorder in Pregnancy: A Cohort Study.

Mullins N, Galvin SL, Ramage M, Gannon M, Lorenz K, Sager B, Coulson CC.

J Addict Med. 2019 Sep 17. doi: 10.1097/ADM.0000000000000562.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/31567599

The Impact of Hepatitis C Virus Infection on Buprenorphine Dose in Pregnancy.

McDowell ML, Tonismae TR, Slaven JE, Abernathy MP, Shanks AL, Benjamin TD, Quinney SK.

Am J Perinatol. 2019 Oct 26. doi: 10.1055/s-0039-1698838.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/31655490

U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

I, Surgeon General VADM Jerome Adams, am emphasizing the importance of protecting our Nation from the health risks of marijuana use in adolescence and during pregnancy. Recent increases in access to marijuana and in its potency, along with misperceptions of safety of marijuana endanger our most precious resource, our nation’s youth. (Office of the Surgeon General, USA, November 2019)

https://www.hhs.gov/surgeongeneral/reports-and-publications/addiction-and-substance-misuse/advisory-on-marijuana-use-and-developing-brain/index.html

Educational achievement at age 9.5 years of children born to mothers maintained on methadone during pregnancy.

Lee SJ, Woodward LJ, Henderson JMT (2019) 

PLoS ONE 14(10): e0223685. doi.org/10.1371/journal.pone.0223685

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223685

Use of Kratom, an Opioid-like Traditional Herb, in Pregnancy.

Smid MC, Charles JE, Gordon AJ, Wright TE.

Obstet Gynecol. 2018 Oct;132(4):926-928. doi: 10.1097/AOG.0000000000002871.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30204686

State Strategies to Address Opioid Use Disorder Among Pregnant and Postpartum Women and Infants Prenatally Exposed to Substances, Including Infants with Neonatal Abstinence Syndrome.

Kroelinger CD, Rice ME, Cox S, et al. 

MMWR Morb Mortal Wkly Rep 2019;68:777–783. DOI: doi.org/10.15585/mmwr.mm6836a1

https://www.cdc.gov/mmwr/volumes/68/wr/mm6836a1.htm

Prenatal Exposure to Methamphetamine: Up-Regulation of Brain Receptor Genes.

Zoubková H, Tomášková A, Nohejlová K, Černá M, Šlamberová R.

Front Neurosci. 2019 Aug 1;13:771. doi: 10.3389/fnins.2019.00771.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686742/

Buprenorphine for Opioid Use Disorders during Pregnancy: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines [Internet].

Edge R, Butcher R.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 May 9. PMID: 31479216

https://www.ncbi.nlm.nih.gov/books/NBK545816/

Relation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth.

Margulis AV, Hernandez-Diaz S, McElrath T, Rothman KJ, Plana E, Almqvist C, et al. (2019) 

PLoS ONE 14(8): e0214180. doi.org/10.1371/journal.pone.0214180

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214180

Prenatal exposure to opioid maintenance treatment and neonatal outcomes: Nationwide registry studies from the Czech Republic and Norway.

Handal M, Nechanská B, Skurtveit S, Lund IO, Gabrhelík R, Engeland A, Mravčík V.

Pharmacol Res Perspect. 2019 Aug 14;7(5):e00501. doi: 10.1002/prp2.501.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694203/

Association of Maternal Use of Benzodiazepines and Z-Hypnotics During Pregnancy With Motor and Communication Skills and Attention-Deficit/Hyperactivity Disorder Symptoms in Preschoolers.

Lupattelli A, Chambers CD, Bandoli G, Handal M, Skurtveit S, Nordeng H.

JAMA Netw Open. 2019 Apr 5;2(4):e191435. doi: 10.1001/jamanetworkopen.2019.1435. Erratum in: JAMA Netw Open. 2019 May 3;2(5):e194291. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450329/

Association of prenatal exposure to benzodiazepines and child internalizing problems: A sibling-controlled cohort study.

Brandlistuen RE, Ystrom E, Hernandez-Diaz S, Skurtveit S, Selmer R, Handal M, et al. (2017) 

PLoS ONE 12(7): e0181042. doi.org/10.1371/journal.pone.0181042

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181042

Opioids Affect the Fetal Brain: Reframing the Detoxification Debate.

Caritis SN, Panigrahy A.

Am J Obstet Gynecol. 2019 Jul 16. pii: S0002-9378(19)30906-8. doi: 10.1016/j.ajog.2019.07.022.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/31323217

Treating women with opioid use disorder during pregnancy in Appalachia: Initial neonatal outcomes following buprenorphine + naloxone exposure.

Nguyen L, Lander LR, O'Grady KE, Marshalek PJ, Schmidt A, Kelly AK, Jones HE.

Am J Addict. 2018 Mar;27(2):92-96. doi: 10.1111/ajad.12687. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929133/

  1. Maternal buprenorphine treatment during pregnancy and maternal physiology.
  2. Impact of prenatal exposure to benzodiazepines and z-hypnotics on behavioral problems at 5 years of age: A study from the Norwegian Mother and Child Cohort Study.
  3. Substance Use In Pregnancy.
  4. Medications to Treat Opioid Use During Pregnancy – An info sheet for providers
  5. Pregnancy Planning for Women Treated for Opioid Use Disorder