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Opioids and Cardiac Arrhythmia: A Literature Review.

Behzadi M, Joukar S, Beik A.

Med Princ Pract. 2018 Aug 2. doi: 10.1159/000492616.

https://www.karger.com/Article/Pdf/492616

QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications.

Fernandes FM, Silva EP, Martins RR, Oliveira AG (2018) 

PLoS ONE 13(6): e0199028. doi.org/10.1371/journal.pone.0199028

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199028

The Use of First Line Highly Active Anti-Retroviral Therapy (HAART) is Not Associated with Qtc Prolongation in HIV Patients.

Ogunmodede J, Kolo P, Katibi I, Omotoso A.

Ethiop J Health Sci. 2017 Nov;27(6):613-620.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811940/

Malignant Ventricular Arrhythmias Resulting From Drug-Induced QTc Prolongation: A Retrospective Study.

De Vecchis R, Ariano C, Di Biase G, Noutsias M.

J Clin Med Res. 2018 Jul;10(7):593-600. doi: 10.14740/jocmr3470w. Epub 2018 Jun 4.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997417/

Long QT Syndrome.

Alders M, Bikker H, Christiaans I.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2003 Feb 20 [updated 2018 Feb 8].

PMID: 20301308

https://www.ncbi.nlm.nih.gov/books/NBK1129/

Significance of prolonged QTc in acute exacerbations of COPD requiring hospitalization.

Van Oekelen O, Vermeersch K, Everaerts S, Vandenberk B, Willems R, Janssens W.

Int J Chron Obstruct Pulmon Dis. 2018 Jun 14;13:1937-1947. doi: 10.2147/COPD.S157630. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005315/

Limited Evidence for Risk Factors for Proarrhythmia and Sudden Cardiac Death in Patients Using Antidepressants: Dutch Consensus on ECG Monitoring.

Simoons M, Seldenrijk A, Mulder H, Birkenhäger T, Groothedde-Kuyvenhoven M, Kok R, Kramers C, Verbeeck W, Westra M, van Roon E, Bakker R, Ruhé H.

Drug Saf. 2018 Feb 26. doi: 10.1007/s40264-018-0649-z.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29484613

QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: A Tuberculosis Network European Trialsgroup (TBnet) study.

Guglielmetti L, Tiberi S, Burman M, Kunst H, Wejse C, Togonidze T, Bothamley G, Lange C; TBNET.

Eur Respir J. 2018 Jun 7. pii: 1800537. doi: 10.1183/13993003.00537-2018.

Abstract

http://erj.ersjournals.com/content/early/2018/05/31/13993003.00537-2018

Prolongation of the QTc interval in HIV-infected individuals compared to the general population

Reinsch, N., Arendt, M., Geisel, M.H. et al. Infection (2017) 45: 659. doi.org/10.1007/s15010-017-1053-9

Abstract

https://link.springer.com/article/10.1007%2Fs15010-017-1053-9

Tramadol Hydrochloride at Steady State Lacks Clinically Relevant QTc Interval Increases in Healthy Adults.

Massarella J, Ariyawansa J, Natarajan J, Francke S, Murtaugh T, DeLemos B, Vaughan S, Fonseca S.

Clin Pharmacol Drug Dev. 2018 May 18. doi: 10.1002/cpdd.473.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29775246

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.

Schulze V, Stoetzer C, O'Reilly AO, Eberhardt E, Foadi N, Ahrens J, Wegner F, Lampert A, de la Roche J, Leffler A.

Br J Pharmacol. 2014 Jan;171(2):427-37. doi: 10.1111/bph.12465.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904262/

Effects of Methadone on Corrected Q-T Interval Prolongation in Critically Ill Children.

Heath TS, Greenberg RG, Hupp SR, Turner DA, Hornik CP, Zimmerman KO.

J Pediatr Pharmacol Ther. 2018 Mar-Apr;23(2):119-124. doi: 10.5863/1551-6776-23.2.119.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916439/

EKG: QT - Verlängerung durch Methadon

FOSUMOS – Forum Suchtmedizin Ostschweiz, Themenseite

https://www.fosumos.ch/fosumos/index.php/de/heroin/methadon/qt-verlaengerung

Drug-induced Proarrhythmia and Torsade de Pointes: A Primer for Students and Practitioners of Medicine and Pharmacy.

Turner JR, Rodriguez I, Mantovani E, Gintant G, Kowey PR, Klotzbaugh RJ, Prasad K, Sager PT, Stockbridge N, Strnadova C; Cardiac Safety Research Consortium.

J Clin Pharmacol. 2018 Apr 19. doi: 10.1002/jcph.1129.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29672845

Psychopharmakaassoziierte QTc-Intervall-Verlängerung und Torsade de Pointes

QTc Prolongation by Psychotropic Drugs and the Risk of Torsade de Pointes

Dtsch Arztebl Int 2011; 108(41): 687-93; DOI: 10.3238/arztebl.2011.0687

Wenzel-Seifert, Katharina; Wittmann, Markus; Haen, Ekkehard

https://www.aerzteblatt.de/archiv/108561/Psychopharmakaassoziierte-QTc-Intervall-Verlaengerung-und-Torsade-de-Pointes

Impact of Drug Induced Long QT Syndrome: A Systematic Review.

Arunachalam K, Lakshmanan S, Maan A, Kumar N, Dominic P.

J Clin Med Res. 2018 May;10(5):384-390. doi: 10.14740/jocmr3338w.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862085/

Gefährliche QTc-Verlängerung durch Methadon

Barbara Dezulian, Nadjibulah Gholami, Philip Bruggmann

Arud Zentren für Suchtmedizin, Zürich

SWISS MEDICAL FORUM – SCHWEIZERISCHES MEDIZIN-FORUM 2016;16(7):173–175

https://medicalforum.ch/de/resource/jf/journal/file/download/article/smf/de/smf.2016.02543/smf_02543.pdf/

Electrocardiogram Changes with Acute Alcohol Intoxication: A Systematic Review.

Raheja H, Namana V, Chopra K, Sinha A, Gupta SS, Kamholz S, Moskovits N, Shani J, Hollander G.

Open Cardiovasc Med J. 2018 Feb 12;12:1-6. doi: 10.2174/1874192401812010001.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838641/

Methadon induzierte QTc Verlängerungen im EKG - ein dosis- und geschlechterabhängiger Effekt

Nathalie Brunner, Luis Falcato, Philip Bruggmann

ARUD Zürich (Arbeitsgemeinschaft für risikoarmen Umgang mit Drogen) Schweiz, www.arud-zh.ch

Präsentiert am 9. Interdisziplinären Kongress für Suchtmedizin, München, 3. – 5. Juli 2008

https://praxis-suchtmedizin.ch/fosumos/images/stories/heroin/qtc%20nathalie%20brunner%20poster%20arud%20juli%2008.pdf

QTc prolongation after ADHD medication.

Snircova E, Marcincakova Husarova V, Ondrejka I, Hrtanek I, Farsky I, Nosalova G.

Neuro Endocrinol Lett. 2018 Feb 6;38(8):549-554.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29504733

Presence or Absence of QTc Prolongation in Buprenorphine-Naloxone Among Youth With Opioid Dependence.

Poole SA, Pecoraro A, Subramaniam G, Woody G, Vetter VL.

J Addict Med. 2016 Jan-Feb;10(1):26-33. doi: 10.1097/ADM.0000000000000176.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733605/

The Clue Is in the U Wave: Torsades de Pointes Ventricular Tachycardia in a Hypokalemic Woman on Methadone.

Fitzpatrick JK, Goldschlager N.

Ann Emerg Med. 2018 Apr;71(4):473-476. doi: 10.1016/j.annemergmed.2017.09.007.

http://www.annemergmed.com/article/S0196-0644(17)31656-6/fulltext

Sustained release oral morphine as an alternative to methadone for the treatment of opioid-use disorder post Torsades de Pointes cardiac arrest.

Walton G, Nolan S, Sutherland C, Ahamad K.

BMJ Case Rep. 2015 Sep 21;2015. pii: bcr2015210239. doi: 10.1136/bcr-2015-210239.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577656/

Regarding Methadone and the QTc Interval: Paucity of Clinically Significant Factors in a Retrospective Cohort, Gavin Bart et al.

Stoklosa T, Haber P.

J Addict Med. 2018 Mar/Apr;12(2):167. doi: 10.1097/ADM.0000000000000382.

https://journals.lww.com/journaladdictionmedicine/Citation/2018/04000/Regarding_Methadone_and_the_QTc_Interval___Paucity.14.aspx

QTc interval screening in an opioid treatment program.

Katz DF, Sun J, Khatri V, Kao D, Bucher-Bartelson B, Traut C, Lundin-Martinez J, Goodman M, Mehler PS, Krantz MJ.

Am J Cardiol. 2013 Oct 1;112(7):1013-8. doi: 10.1016/j.amjcard.2013.05.037.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361084/

Liver cirrhosis-effect on QT interval and cardiac autonomic nervous system activity.

Tsiompanidis E, Siakavellas SI, Tentolouris A, Eleftheriadou I, Chorepsima S, Manolakis A, Oikonomou K, Tentolouris N.

World J Gastrointest Pathophysiol. 2018 Feb 15;9(1):28-36. doi: 10.4291/wjgp.v9.i1.28.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823700/