A- A A+

Prolonged QTc in HIV-Infected Patients: A Need for Routine ECG Screening.

Myerson M, Kaplan-Lewis E, Poltavskiy E, Ferris D, Bang H.

J Int Assoc Provid AIDS Care. 2019 Jan-Dec;18:2325958219833926. doi: 10.1177/2325958219833926.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435291/

Assessment of the risk of QT-interval prolongation associated with potential drug-drug interactions in patients admitted to Intensive Care Units.

Fernandes FM, da Silva Paulino AM, Sedda BC, da Silva EP, Martins RR, Oliveira AG.

Saudi Pharm J. 2019 Feb;27(2):229-234. doi: 10.1016/j.jsps.2018.11.003. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362170/

Drug-induced prolonged corrected QT interval in patients with methadone and opium overdose

Davood Soroosh, Mahbubeh Neamatshahi, Bahram Zarmehri, Samaneh Nakhaee and Omid Mehrpour

Substance Abuse Treatment, Prevention, and Policy 2019, 14:8, doi.org/10.1186/s13011-019-0196-3

https://substanceabusepolicy.biomedcentral.com/articles/10.1186/s13011-019-0196-3

Methadone Safety: A Clinical Practice Guideline From the American Pain Society and College on Problems of Drug Dependence, in Collaboration With the Heart Rhythm Society

Chou, Roger et al.

The Journal of Pain , Volume 15 , Issue 4 , 321 - 337 

https://www.jpain.org/article/S1526-5900(14)00522-7/fulltext

A literature-based algorithm for the assessment, management, and monitoring of drug-induced QTc prolongation in the psychiatric population.

Zolezzi M, Cheung L.

Neuropsychiatr Dis Treat. 2018 Dec 24;15:105-114. doi: 10.2147/NDT.S186474. eCollection 2019. Review.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309020

Trends in reporting methadone-associated cardiac arrhythmia, 1997-2011: an analysis of registry data. 

Kao D, Bucher Bartelson B, Khatri V, Dart R, Mehler PS, Katz D, Krantz MJ.

Ann Intern Med. 2013 May 21;158(10):735-40. doi: 10.7326/0003-4819-158-10-201305210-00008.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793842/

Substitution of (R,S)-methadone by (R)-methadone: Impact on QTc interval.

Ansermot N, Albayrak O, Schläpfer J, Crettol S, Croquette-Krokar M, Bourquin M, Déglon JJ, Faouzi M, Scherbaum N, Eap CB.

Arch Intern Med. 2010 Mar 22;170(6):529-36. 

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/774582

QT length during methadone maintenance treatment: gene × dose interaction.

Zerdazi EH, Vorspan F, Marees AT, Naccache F, Lepine JP, Laplanche JL, Prince N, Marie-Claire C, Bellivier F, Mouly S, Bloch V.

Fundam Clin Pharmacol. 2019 Feb;33(1):96-106. doi: 10.1111/fcp.12405.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30086202

Evaluation of QTc Interval Prolongation Among Patients With Cancer Using Enteral Methadone.

Lovell AG, Protus BM, Saphire ML, Kale SS, Lehman A, Hartman A.

Am J Hosp Palliat Care. 2018 Nov 14:1049909118811904. doi: 10.1177/1049909118811904.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30428683

Predictors of electrocardiographic QT interval prolongation in men with HIV.

Wu KC, Zhang L, Haberlen SA, Ashikaga H, Brown TT, Budoff MJ, D'Souza G, Kingsley LA, Palella FJ, Margolick JB, Martínez-Maza O, Soliman EZ, Post WS.

Heart. 2018 Oct 26. pii: heartjnl-2018-313667. doi: 10.1136/heartjnl-2018-313667.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30366934

Q-T interval prolongation in cirrhosis: Relationship and severity.

Hajiaghamohammadi AA, Daee MM, Zargar A, Ahmadi-Gooraji S, Rahban A, Attaran F.

Caspian J Intern Med. 2018 Summer;9(3):239-243. doi: 10.22088/cjim.9.3.239.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121343/

Liver Fibrosis Is Associated With Corrected QT Prolongation During Ledipasvir/Sofosbuvir Treatment for Patients With Chronic Hepatitis C.

Tahata Y, Sakamori R, Urabe A, Morishita N, Yamada R, Yakushijin T, Hiramatsu N, Doi Y, Kaneko A, Hagiwara H, Yamada Y, Hijioka T, Inada M, Tamura S, Imai Y, Furuta K, Kodama T, Hikita H, Tatsumi T, Takehara T.

Hepatol Commun. 2018 Aug 6;2(8):884-892. doi: 10.1002/hep4.1206. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078212/

QT length during methadone maintenance treatment: Gene x dose interaction.

Zerdazi EH, Vorspan F, Marees AT, Naccache F, Lepine JP, Laplanche JL, Prince N, Marie-Claire C, Bellivier F, Mouly S, Bloch V.

Fundam Clin Pharmacol. 2018 Aug 7. doi: 10.1111/fcp.12405.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30086202

Opioids and Cardiac Arrhythmia: A Literature Review.

Behzadi M, Joukar S, Beik A.

Med Princ Pract. 2018 Aug 2. doi: 10.1159/000492616.

https://www.karger.com/Article/Pdf/492616

QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications.

Fernandes FM, Silva EP, Martins RR, Oliveira AG (2018) 

PLoS ONE 13(6): e0199028. doi.org/10.1371/journal.pone.0199028

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199028

Malignant Ventricular Arrhythmias Resulting From Drug-Induced QTc Prolongation: A Retrospective Study.

De Vecchis R, Ariano C, Di Biase G, Noutsias M.

J Clin Med Res. 2018 Jul;10(7):593-600. doi: 10.14740/jocmr3470w. Epub 2018 Jun 4.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997417/

Significance of prolonged QTc in acute exacerbations of COPD requiring hospitalization.

Van Oekelen O, Vermeersch K, Everaerts S, Vandenberk B, Willems R, Janssens W.

Int J Chron Obstruct Pulmon Dis. 2018 Jun 14;13:1937-1947. doi: 10.2147/COPD.S157630. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005315/

QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: A Tuberculosis Network European Trialsgroup (TBnet) study.

Guglielmetti L, Tiberi S, Burman M, Kunst H, Wejse C, Togonidze T, Bothamley G, Lange C; TBNET.

Eur Respir J. 2018 Jun 7. pii: 1800537. doi: 10.1183/13993003.00537-2018.

Abstract

http://erj.ersjournals.com/content/early/2018/05/31/13993003.00537-2018

Tramadol Hydrochloride at Steady State Lacks Clinically Relevant QTc Interval Increases in Healthy Adults.

Massarella J, Ariyawansa J, Natarajan J, Francke S, Murtaugh T, DeLemos B, Vaughan S, Fonseca S.

Clin Pharmacol Drug Dev. 2018 May 18. doi: 10.1002/cpdd.473.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29775246

Effects of Methadone on Corrected Q-T Interval Prolongation in Critically Ill Children.

Heath TS, Greenberg RG, Hupp SR, Turner DA, Hornik CP, Zimmerman KO.

J Pediatr Pharmacol Ther. 2018 Mar-Apr;23(2):119-124. doi: 10.5863/1551-6776-23.2.119.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916439/

Drug-induced Proarrhythmia and Torsade de Pointes: A Primer for Students and Practitioners of Medicine and Pharmacy.

Turner JR, Rodriguez I, Mantovani E, Gintant G, Kowey PR, Klotzbaugh RJ, Prasad K, Sager PT, Stockbridge N, Strnadova C; Cardiac Safety Research Consortium.

J Clin Pharmacol. 2018 Apr 19. doi: 10.1002/jcph.1129.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29672845

Impact of Drug Induced Long QT Syndrome: A Systematic Review.

Arunachalam K, Lakshmanan S, Maan A, Kumar N, Dominic P.

J Clin Med Res. 2018 May;10(5):384-390. doi: 10.14740/jocmr3338w.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862085/

Electrocardiogram Changes with Acute Alcohol Intoxication: A Systematic Review.

Raheja H, Namana V, Chopra K, Sinha A, Gupta SS, Kamholz S, Moskovits N, Shani J, Hollander G.

Open Cardiovasc Med J. 2018 Feb 12;12:1-6. doi: 10.2174/1874192401812010001.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838641/

QTc prolongation after ADHD medication.

Snircova E, Marcincakova Husarova V, Ondrejka I, Hrtanek I, Farsky I, Nosalova G.

Neuro Endocrinol Lett. 2018 Feb 6;38(8):549-554.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29504733

The Clue Is in the U Wave: Torsades de Pointes Ventricular Tachycardia in a Hypokalemic Woman on Methadone.

Fitzpatrick JK, Goldschlager N.

Ann Emerg Med. 2018 Apr;71(4):473-476. doi: 10.1016/j.annemergmed.2017.09.007.

http://www.annemergmed.com/article/S0196-0644(17)31656-6/fulltext

Regarding Methadone and the QTc Interval: Paucity of Clinically Significant Factors in a Retrospective Cohort, Gavin Bart et al.

Stoklosa T, Haber P.

J Addict Med. 2018 Mar/Apr;12(2):167. doi: 10.1097/ADM.0000000000000382.

https://journals.lww.com/journaladdictionmedicine/Citation/2018/04000/Regarding_Methadone_and_the_QTc_Interval___Paucity.14.aspx

Liver cirrhosis-effect on QT interval and cardiac autonomic nervous system activity.

Tsiompanidis E, Siakavellas SI, Tentolouris A, Eleftheriadou I, Chorepsima S, Manolakis A, Oikonomou K, Tentolouris N.

World J Gastrointest Pathophysiol. 2018 Feb 15;9(1):28-36. doi: 10.4291/wjgp.v9.i1.28.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823700/

The Use of First Line Highly Active Anti-Retroviral Therapy (HAART) is Not Associated with Qtc Prolongation in HIV Patients.

Ogunmodede J, Kolo P, Katibi I, Omotoso A.

Ethiop J Health Sci. 2017 Nov;27(6):613-620.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811940/

Long QT Syndrome.

Alders M, Bikker H, Christiaans I.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2003 Feb 20 [updated 2018 Feb 8].

PMID: 20301308

https://www.ncbi.nlm.nih.gov/books/NBK1129/

Limited Evidence for Risk Factors for Proarrhythmia and Sudden Cardiac Death in Patients Using Antidepressants: Dutch Consensus on ECG Monitoring.

Simoons M, Seldenrijk A, Mulder H, Birkenhäger T, Groothedde-Kuyvenhoven M, Kok R, Kramers C, Verbeeck W, Westra M, van Roon E, Bakker R, Ruhé H.

Drug Saf. 2018 Feb 26. doi: 10.1007/s40264-018-0649-z.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29484613