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Acute poisoning with gamma-hydroxybutyrate. Akutt forgiftning med gammahydroksybutyrat. 

Aronsen AC, Brekke M, Vallersnes OM. 

Tidsskr Nor Laegeforen. 2020;140(10):10.4045/tidsskr.19.0780. Published 2020 Jun 29.

https://tidsskriftet.no/en/2020/06/kort-rapport/acute-poisoning-gamma-hydroxybutyrate

One Is Not Enough: Understanding and Modeling Polysubstance Use. 

Crummy EA, O'Neal TJ, Baskin BM, Ferguson SM. 

Front Neurosci. 2020;14:569. Published 2020 Jun 16. doi:10.3389/fnins.2020.00569

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309369/

Association of Ketamine With Psychiatric Symptoms and Implications for Its Therapeutic Use and for Understanding Schizophrenia: A Systematic Review and Meta-analysis.

Beck K, Hindley G, Borgan F, et al. 

JAMA Netw Open. 2020;3(5):e204693. doi:10.1001/jamanetworkopen.2020.4693

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2766225

Why Isotonitezene Is Not Yet the “New Fentanyl” 

In the span of about a year, isotonitazene, a novel psychoactive substance (NPS), went from being practically unheard of to being implicated in a fatal overdose spike in the Midwest. While some researchers and media reports are warning about the emergence of the designer drug, one harm reductionist from the region cautions against singling it out. (Filter Magazine, USA, 21.05.2020)

https://filtermag.org/isotonitezene/

An Insight into Z-Drug Abuse and Dependence: An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions.

Schifano F, Chiappini S, Corkery JM, Guirguis A.

Int J Neuropsychopharmacol. 2019 Apr 1;22(4):270-277. doi: 10.1093/ijnp/pyz007.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441128/

The problem of alpha-PVP in Russia and other post-Soviet states
On Russian YouTube, there are videos of alpha-PVP users, acting in bizarre and uncontrollable ways. It’s just one small sign of a vast, hidden epidemic. Read this report from Sam Iravani! (Drug Reporter, Ungarn, 24.03.2020)

https://drogriporter.hu/en/alphapvp/

Hirnforschung: Ritalin macht nicht klüger, motiviert aber zum Lernen

Providence, Rhode Island − Die Einnahme von Methylphenidat, besser bekannt unter dem Markennamen Ritalin, verbessert nicht die kognitiven Fähigkeiten, sie könnte allerdings die Motivation fördern, sich schwierigen Aufgaben zu stellen, weil die Belohnung nach der erfolgreichen Absolvierung als stärker empfunden wird. (aerzteblatt.de, 31.03.2020)

https://www.aerzteblatt.de/nachrichten/111273/Hirnforschung-Ritalin-macht-nicht-klueger-motiviert-aber-zum-Lernen

USA. Drugs of Abuse - A DEA Resource Guide: 2020 EDITION 

Drugs of Abuse, A DEA Resource Guide, is designed to be a reliable resource on the most commonly abused and misused drugs in the United States. This comprehensive guide provides important information about the harms and consequences of drug use by describing a drug’s effects on the body and mind, overdose potential, origin, legal status, and other key facts. (Drug Enforcement Administration, U.S. Department of Justice, April 2020) 

https://www.getsmartaboutdrugs.gov/sites/getsmartaboutdrugs.com/files/publications/Drugs%20of%20Abuse%202020-Web%20Version-508%20compliant.pdf

Drugs in Iran: A New IranWire Series 

The illicit drugs trade in Iran has shaped countless lives, exacerbated by punitive and misguided polices that have left some of society’s most vulnerable in the cold. In an exclusive new series for IranWire, academic Dariush Farahani lifts the lid on an under-reported contemporary crisis. (Iran wire, Iran, 23.03.2020)

https://iranwire.com/en/features/6840

Kenia. Meet Beauty Therapist Saving Female Heroin Addicts 

But this isn’t just any beauty parlour. The women who seek Naima’s services are addicted to heroin, or they’re recovering.

Housed in the Reachout Centre Trust, which helps Mombasa residents fight drug addiction, it opened last year with a view to attracting more female users to its services that include HIV testing, counselling, methadone treatment and cervical cancer screening. (The Guardian, UK, 18.03.20209

https://www.theguardian.com/global-development/2020/mar/18/you-are-beautiful-the-kenyan-beauty-parlour-serving-female-heroin-users

Neuroethical issues in cognitive enhancement: Modafinil as the example of a workplace drug?

Brühl AB, d'Angelo C, Sahakian BJ.

Brain Neurosci Adv. 2019 Feb 15;3:2398212818816018. doi: 10.1177/2398212818816018. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058249/

Cardiovascular and Autonomic Responses to Energy Drinks-Clinical Implications.

Somers KR, Svatikova A.

J Clin Med. 2020 Feb 5;9(2). pii: E431. doi: 10.3390/jcm9020431. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073550/

Identification of the New Psychoactive Substance Dibutylone.

Wang KD, Cao FQ, Jiang X, Chen H, Yuan XL, Chen YS, Hu JJ.

Fa Yi Xue Za Zhi. 2019 Dec;35(6):682-686. doi: 10.12116/j.issn.1004-5619.2019.06.007. 

http://www.fyxzz.cn/CN/10.12116/j.issn.1004-5619.2019.06.007

Teratogenität von Modafinil bestätigt

Odense/Dänemark – Die Einnahme des Psychostimulans Modafinil in der Schwangerschaft hat in einer bevölkerungsbasierten Studie im amerikanischen Ärzteblatt (JAMA 2020; 323: 374-376) das Risiko von Fehlbildungen verdreifacht. Die Studie bestätigt eine im letzten Jahr in einem Rote-Hand-Brief veröffentlichte Warnung. (aerzteblatt.de, 29.01.2020)

https://www.aerzteblatt.de/nachrichten/108988/Teratogenitaet-von-Modafinil-bestaetigt

The overwhelming issue of Drug Facilitated Sexual Assaults (DFSA): the case of GHB.

Berretta P, Varì MR.

Clin Ter. 2020 Jan-Feb;170(1):e44-e45. doi: 10.7417/CT.2020.2187.

http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/556/218

Treatments for people who use anabolic androgenic steroids: a scoping review.

Bates, G., Van Hout, M., Teck, J.T.W. et al. 

Harm Reduct J 16, 75 (2019) doi:10.1186/s12954-019-0343-1

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-019-0343-1

Psilocybin and MDMA reduce costly punishment in the Ultimatum Game.

Gabay AS, Carhart-Harris RL, Mazibuko N, Kempton MJ, Morrison PD, Nutt DJ, Mehta MA.

Sci Rep. 2018 May 29;8(1):8236. doi: 10.1038/s41598-018-26656-2.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974271/

Polysubstance use patterns and novel synthetics: A cluster analysis from three U.S. cities.

Elliott L, Haddock CK, Campos S, Benoit E (2019) 

PLoS ONE 14(12): e0225273. doi.org/10.1371/journal.pone.0225273

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225273

Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers.

Family N, Maillet EL, Williams LTJ, Krediet E, Carhart-Harris RL, Williams TM, Nichols CD, Goble DJ, Raz S.

Psychopharmacology (Berl). 2019 Dec 18. doi: 10.1007/s00213-019-05417-7. 

https://link.springer.com/article/10.1007%2Fs00213-019-05417-7

scobel - Drogen als Medizin (Video)

Von der illegalen Droge zum Heilmittel: Werden psychedelische Substanzen wie LSD oder "Zauberpilze" schon bald als Arzneien gegen Depressionen, Angststörungen und Schmerzen eingesetzt? (ZDF, 21.11.2019, Video, 58:00)

https://www.3sat.de/wissen/scobel/scobel---drogen-als-medizin-100.html

«Psychedelika helfen bei Depression und Sucht»

Langfristig wirken Meditation und der Zauberpilz-Wirkstoff Psilocybin zusammen achtmal stärker als Meditation allein, sagt der Zürcher Hirnforscher Franz Vollenweider. (Beobachter, Schweiz, 25.10.2019)

https://www.beobachter.ch/gesundheit/medizin-krankheit/forschung-psychedelika-helfen-bei-depression-und-sucht

Twenty percent better with 20 micrograms? A qualitative study of psychedelic microdosing self-rapports and discussions on YouTube.

Andersson, M., Kjellgren, A. 

Harm Reduct J 16, 63 (2019) doi:10.1186/s12954-019-0333-3

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-019-0333-3

Einzelne Ketamin-Infusion senkt problematischen Alkoholkonsum

London – Das Narkotikum Ketamin, das wegen seiner halluzinogenen Wirkung als Party­droge beliebt ist und in den USA in „Ketamin Clinics“ zur Behandlung von refraktären Depressionen eingesetzt wird, könnte nach einer Pilotstudie in Nature Communications (2019; doi: 10.1038/s41467-019-13162-w) Alkoholabhängigen helfen, sich von ihren „maladaptive reward memories“ zu befreien. (aerzteblatt.de, 26.11.2019)

https://www.aerzteblatt.de/nachrichten/107754/Einzelne-Ketamin-Infusion-senkt-problematischen-Alkoholkonsum

Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories.

Das, R.K., Gale, G., Walsh, K. et al. 

Nat Commun 10, 5187 (2019) doi:10.1038/s41467-019-13162-w

https://www.nature.com/articles/s41467-019-13162-w

Global Drug Survey: Sagen Sie uns, welche Drogen Sie nehmen 

Bierchen am Abend, Dampfen in der Pause, Ecstasy im Club: ZEIT ONLINE ruft erneut zur weltgrößten Drogenumfrage auf – damit Ihnen der Rausch weniger schadet. (Zeit online, 14.11.2019)

https://www.zeit.de/wissen/gesundheit/2019-11/global-drug-survey-drogen-alkohol-cannabis-umfrage

Global Drug Survey 2020

Welcome to GDS2020. Thank you for taking part and adding your experience to the world’s largest drug survey. Global Drug Survey (GDS) is independent and free from the influence of government funding or commercial interests. Funds we generate go into running the survey and creating free harm reduction tools.
Our international team is committed to helping make drug use safer regardless of the legal status of the drug and promoting honest conversations about drug use across the world.
GDS2020 is hosted on an encrypted survey platform. It’s anonymous and confidential. You don’t need to give any personally identifiable details. We don’t record your IP address.
This year’s core survey will take most people 20-30 minutes. At the end of each core drug section we will give you feedback about how your frequency of use compares to other people who have taken that drug and taken part in the GDS over the last 2 years, or in the case of alcohol what level of risk your current drinking may be placing you at. (GDS2020, November 2019)

https://www.globaldrugsurvey.world/s3/Global-Drug-Survey-2020-Launch-version

Medicines associated with dependence or withdrawal: a mixed-methods public health review and national database study in England.

Marsden J, White M, Annand F, Burkinshaw P, Carville S, Eastwood B, Kelleher M, Knight J, O'Connor R, Tran A, Willey P, Greaves F, Taylor S.

Lancet Psychiatry. 2019 Nov;6(11):935-950. doi: 10.1016/S2215-0366(19)30331-1.

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(19)30331-1/fulltext

Drug Use - Series from the Lancet journals

Executive Summary

The drug use landscape is dynamic and changing. Changes in public attitudes and laws towards drug use have occurred in an increasing number of countries. Global drug production and consumption are increasing as are the risks and harms to health, while new substances continue to emerge. This Series focuses on opioids, cannabinoids, stimulants, and new psychoactive substances. The Series authors review the evidence on the epidemiology of drug use and related harms and interventions (treatment and policies) to address them. They highlight issues that are likely to become increasingly important in the next decade. (The Lancet, 25.10.2019)

https://www.thelancet.com/series/drug-use

Baden-Württemberg. Suchtforum der Landesstelle: „Drogenabhängigkeit und Medikamentenmissbrauch“ - 26.09.2019

(…) In den letzten Jahren spielt der Medikamentenmissbrauch bei Drogenabhängigen eine immer größere Rolle. Neben der Tatsache, dass in der Drogenszene alle dem BtMG unterliegenden Medikamente, wie Subutex, Polamidon und andere Opioide, aber auch Methylphenidat zu sehr günstigen Preisen gehandelt werden, haben wir in den letzten Jahren den zunehmenden Trend, dass sich Dro-genabhängige von Fach-und Hausärzten unterschiedliche psychotrop wirksame Medikamente verschreiben lassen. Hier sind insbesondere die Benzodiazepine zu nennen und - in immer stärkerem Maße - der Missbrauch von Pregabalin (Lyrica). Andere Psychopharmaka bis hin zu Antidepressiva werden ebenfalls als Beikonsum zu den klassischen illegalen Drogen missbraucht. (Landesstelle für SuchtfragenderLiga der freien Wohlfahrtspflegein Baden-Württemberg e.V., Landesstellenbrief, 08/2019, 24.10.2019)

http://www.suchtfragen.de/landesstellenbrief/2019/2019_08/2019-Bericht-Suchtforum.pdf