Compassionate Use: Statt Propofol und Midazolam: Klinik testet Remimazolam
Berlin - In einigen italienischen Krankenhäusern werden verschiedene Wirkstoffe zur Sedierung von Covid-Patienten knapp. Nun wurde mit Remimazolam im Zuge eines Compassionate-Use-Programms ein weiterer Wirkstoff zur Verfügung gestellt, um den Engpass zu lockern. (apotheke adhoc, 02.02.2020)
https://www.apotheke-adhoc.de/nachrichten/detail/internationales/statt-propofol-und-midazolam-klinik-testet-remimazolam-italien-compassionate-use-fuer-remimazolam/
Association Between Benzodiazepine Use With or Without Opioid Use and All-Cause Mortality in the United States, 1999-2015.
Xu KY, Hartz SM, Borodovsky JT, Bierut LJ, Grucza RA.
JAMA Netw Open. 2020;3(12):e2028557. doi:10.1001/jamanetworkopen.2020.28557
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2773826
Benzodiazepine: FDA will Warnungen vor Abhängigkeit verschärfen
Silver Spring/Maryland – Ein offenbar zunehmender Missbrauch von Benzodiazepinen veranlasst die Arzneimittelbehörde FDA dazu, die Fachinformationen zu verschärfen. Diese sollen künftig umrahmte Warnhinweise enthalten. (aerzteblatt.de, 15.10.2020)
https://www.aerzteblatt.de/nachrichten/116832/Benzodiazepine-FDA-will-Warnungen-vor-Abhaengigkeit-verschaerfen
Concurrent Use of Benzodiazepine by Heroin Users-What Are the Prevalence and the Risks Associated with This Pattern of Use?.
Yamamoto T, Dargan PI, Dines A, et al.
J Med Toxicol. 2019;15(1):4-11. doi:10.1007/s13181-018-0674-4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314928/
Mixing meds: Weighing the pros and cons of adding benzodiazepines to buprenorphine treatment for individuals with opioid use disorder
Benzodiazepines (a class of sedative medications best known by brand names like Valium, Xanax, and Klonopin) may be prescribed to patients who are receiving buprenorphine treatment for opioid use disorder (an opioid agonist medication best known in formulation with naloxone, marketed as Suboxone). Clinicians accept that there are both risks, and potential benefits associated with combining these medications. To help aid clinical recommendations, Park and colleagues examined some of the risks and benefits associated with prescribing buprenorphine and benzodiazepines together using government records from the state of Massachusetts. (Recovery Research Institute, USA, Juni 2020)
https://www.recoveryanswers.org/research-post/mixing-benzodiazepines-buprenorphine-opioid-use-disorder/
An expanding world of new psychoactive substances-designer benzodiazepines.
Zawilska JB, Wojcieszak J.
Neurotoxicology. 2019 Jul;73:8-16. doi: 10.1016/j.neuro.2019.02.015.
Abstract
https://www.sciencedirect.com/science/article/abs/pii/S0161813X19300178
Combining opioids and benzodiazepines: effects on mortality and severe adverse respiratory events.
Boon M, van Dorp E, Broens S, Overdyk F.
Ann Palliat Med. 2020 Mar;9(2):542-557. doi: 10.21037/apm.2019.12.09.
http://apm.amegroups.com/article/view/35734/29319
A serious adverse drug reaction probably induced by clonazepam: a case report of myotoxicity.
Han X, Wang J.
BMC Pharmacol Toxicol. 2019 Nov 5;20(1):64. doi: 10.1186/s40360-019-0366-y.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833282/
Problematic Medication With Benzodiazepines, "Z-drugs", and Opioid Analgesics.
Buth S, Holzbach R, Martens MS, Neumann-Runde E, Meiners O, Verthein U.
Dtsch Arztebl Int. 2019 Sep 13;116(37):607-614. doi: 10.3238/arztebl.2019.0607.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819700/
nal von minden: Drug-Screen® 7-Aminoclonazepam Schnelltest
Zum Nachweis von 7-Aminoclonazepam in Urin, Cut-off: 200 ng/mL
https://www.nal-vonminden.com/de/fileupload/index/download?id=133
Benzodiazepine: Fluch und Segen - Was Benzodiazepine im Körper bewirken
Daniela Beer, “Product Manager Toxicology“, nal von minden GmbH
Benzodiazepine- Fluch und Segen - Was Benzodiazepine im Körper bewirken - D.Beer
Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit.
Li Y, Ma J, Jin Y, Li N, Zheng R, Mu W, Wang J, Si J, Chen J, Shang H.
Cochrane Database of Systematic Reviews 2020, Issue 2. Art. No.: CD012670. DOI: 10.1002/14651858.CD012670.pub2
Abstract
Is Long-Term Benzodiazepine Use a Risk Factor for Cognitive Decline? Results of a Systematic Review
Danilo Nader and Linda Gowing
Journal of Addiction, Volume 2020, Article ID 1569456, 10 pages, doi.org/10.1155/2020/1569456
https://www.hindawi.com/journals/jad/2020/1569456/
Prescription of benzodiazepines, z-drugs, and gabapentinoids and mortality risk in people receiving opioid agonist treatment: Observational study based on the UK Clinical Practice Research Datalink and Office for National Statistics death records.
Macleod J, Steer C, Tilling K, Cornish R, Marsden J, Millar T, Strang J, Hickman M.
PLoS Med. 2019 Nov 26;16(11):e1002965. doi: 10.1371/journal.pmed.1002965.
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002965
Clonazepam used as single antiepileptic drug to treat people with newly diagnosed epilepsy
Brigo F, Igwe SC, Bragazzi N, Lattanzi S.
Cochrane Database of Systematic Reviews 2019, Issue 11. Art. No.: CD013028. DOI: 10.1002/14651858.CD013028.pub2
Certainty of the evidence
So far, the evidence on the efficacy and tolerability of clonazepam used as a single antiepileptic drug for the treatment of epilepsy is scarce and of very low certainty; hence insufficient to base decisions on its use in monotherapy.
Abstract
https://www.cochrane.org/CD013028/EPILEPSY_clonazepam-used-single-antiepileptic-drug-treat-people-newly-diagnosed-epilepsy
The Evolution of Designer Benzodiazepines - Challenges for detection and monitoring
Maximo J. Marin, MD, and Xander M.R. van Wijk, PhD, DABCC // Date: NOV.1.2019 // Source: Clinical Laboratory News; American Association for Clinical Chemistry (AACC)
https://www.aacc.org/publications/cln/articles/2019/november/the-evolution-of-designer-benzodiazepines
Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study.
Grossi CM, Richardson K, Fox C, Maidment I, Steel N, Loke YK, Arthur A, Myint PK, Campbell N, Boustani M, Robinson L, Brayne C, Matthews FE, Savva GM.
BMC Geriatr. 2019 Oct 21;19(1):276. doi: 10.1186/s12877-019-1280-2.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802337/
Association between benzodiazepines and suicide risk: a matched case-control study.
Cato V, Holländare F, Nordenskjöld A, Sellin T.
BMC Psychiatry. 2019 Oct 26;19(1):317. doi: 10.1186/s12888-019-2312-3.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815437/
Medicines associated with dependence or withdrawal: a mixed-methods public health review and national database study in England.
Marsden J, White M, Annand F, Burkinshaw P, Carville S, Eastwood B, Kelleher M, Knight J, O'Connor R, Tran A, Willey P, Greaves F, Taylor S.
Lancet Psychiatry. 2019 Nov;6(11):935-950. doi: 10.1016/S2215-0366(19)30331-1.
https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(19)30331-1/fulltext
Norwegen. 'The entire pharmaceutical compendium' in the treatment of substance use disorders
Jørg Mørland, Helge Waal
Tidsskr Nor Legeforen 2019, doi: 10.4045/tidsskr.18.0678
Prediction of Drug-Drug Interactions Between Opioids and Overdosed Benzodiazepines Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation.
Ji B, Liu S, Xue Y, He X, Man VH, Xie XQ, Wang J.
Drugs R D. 2019 Sep;19(3):297-305. doi: 10.1007/s40268-019-00282-3.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738369/
Reduction of Benzodiazepine Use in Patients Prescribed Medical Cannabis.
Purcell C, Davis A, Moolman N, Taylor SM.
Cannabis Cannabinoid Res. 2019 Sep 23;4(3):214-218. doi: 10.1089/can.2018.0020.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757237/
An Approach to Evaluate the Effects of Concomitant Prescribing of Opioids and Benzodiazepines on Veteran Deaths and Suicides.
National Academies of Sciences, Engineering, and Medicine. 2019.
Washington, DC: The National Academies Press. doi.org/10.17226/25532.
https://www.nap.edu/download/25532
Originalarbeit: Problematische Medikation von Benzodiazepinen, Z-Substanzen und Opioid-Analgetika - Analyse von Verschreibungsdaten der Gesetzlichen Krankenversicherung der Jahre 2006–2016
Problematic medication with benzodiazepines, “Z-drugs”, and opioid analgesics—an analysis of national health insurance prescription data from 2006–2016
Buth, Sven; Holzbach, Rüdiger; Martens, Marcus-Sebastian; Neumann-Runde, Eike; Meiners, Ommo; Verthein, Uwe
Dtsch Arztebl Int 2019; 116: 607-14; DOI: 10.3238/arztebl.2019.0607
https://www.aerzteblatt.de/medizin/originalarbeiten?aid=209655
Considerations for the use of a loading dose of diazepam for the treatment of benzodiazepine dependence.
Azanza Balmori A, García Álvarez G, Rodríguez Turiel C, Povedano Suárez EA, Muquebil Ali Al Shaban Rodríguez OW.
Adicciones. 2018 Jul 12;30(3):227-228. doi: 10.20882/adicciones.1116. English, Spanish.
http://adicciones.es/index.php/adicciones/article/view/1116
Association of Maternal Use of Benzodiazepines and Z-Hypnotics During Pregnancy With Motor and Communication Skills and Attention-Deficit/Hyperactivity Disorder Symptoms in Preschoolers.
Lupattelli A, Chambers CD, Bandoli G, Handal M, Skurtveit S, Nordeng H.
JAMA Netw Open. 2019 Apr 5;2(4):e191435. doi: 10.1001/jamanetworkopen.2019.1435. Erratum in: JAMA Netw Open. 2019 May 3;2(5):e194291.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450329/
Association of prenatal exposure to benzodiazepines and child internalizing problems: A sibling-controlled cohort study.
Brandlistuen RE, Ystrom E, Hernandez-Diaz S, Skurtveit S, Selmer R, Handal M, et al. (2017)
PLoS ONE 12(7): e0181042. doi.org/10.1371/journal.pone.0181042
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181042
Rates of Physician Coprescribing of Opioids and Benzodiazepines After the Release of the Centers for Disease Control and Prevention Guidelines in 2016.
Jeffery MM, Hooten WM, Jena AB, Ross JS, Shah ND, Karaca-Mandic P.
JAMA Netw Open. 2019 Aug 2;2(8):e198325. doi: 10.1001/jamanetworkopen.2019.8325.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2740781
The Emergence of New Psychoactive Substance (NPS) Benzodiazepines. A Survey of their Prevalence in Opioid Substitution Patients using LC-MS
S.Mc Namara, S.Stokes, J.Nolan
Issue: Ir Med J; Vol 112; No. 7; P970
Therapie der Benzodiazepinabhängigkeit - Treatment of benzodiazepine dependence
Michael Soyka
Fortschr Neurol Psychiatr 2019; 87(04): 259-270, DOI: 10.1055/a-0836-7514
Abstract
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-0836-7514
Seite 1 von 4