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The Doctor with the Magic Touch

We now move to the 1990s.

Dr David Ho, Time Magazine’s 1996 Person of the Year and personal doctor to basketball legend Magic Johnson, talks to our host, Femi Oke, about his role in developing pioneering combination drug therapy. This treatment breakthrough helped transform HIV from a likely death sentence into a manageable condition if you had access to care and medication. (IAS – International AIDS Society, Schweiz, 18.07.2021)

https://podcasts.apple.com/us/podcast/hiv-unmuted/id1565625594

HCV and HIV co-infection among people who inject drugs in Vietnam. 

Thinh VT, Li L, Matthieu D, Hoa VD, Anh NH, Giang LM. 

J Health Soc Sci. 2020 Dec;5(4):573-586. PMID: 34109283; PMCID: PMC8186291.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186291/

Epidemic of HIV infection among persons who inject drugs in mainland China: a series, cross-sectional study. 

Zhang, B., Yan, X., Li, Y. et al. 

Harm Reduct J 18, 63 (2021). doi.org/10.1186/s12954-021-00511-6

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-021-00511-6

40 years of HIV/AIDS: an interview with Peter Piot

Samarasekera, Udani

The Lancet, Volume 397, Issue 10290, 2138 - 2139 

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01212-5/fulltext

HIV Infection and Depression Among Opiate Users in a US Epicenter of the Opioid Epidemic. 

Denis CM, Dominique T, Smith P, Fiore D, Ku YC, Culhane A, Dunbar D, Brown D, Daramay M, Voytek C, Morales KH, Blank MB, Crits-Christoph PF, Douglas SD, Spitsin S, Frank I, Colon-Rivera K, Montaner LJ, Metzger DS, Evans DL. 

AIDS Behav. 2021 Jul;25(7):2230-2239. doi: 10.1007/s10461-020-03151-2. Epub 2021 Jan 15. PMID: 33449236; PMCID: PMC7809894.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809894/

Restrictive Policies Threaten Efforts to Stop 2 West Virginia HIV Outbreaks. 

Kuehn BM. 

JAMA. Published online May 20, 2021. doi:10.1001/jama.2021.7404

https://jamanetwork.com/journals/jama/fullarticle/2780358

Back to the beginning: AIDS and the elusive vaccine (Podcast)

Our first episode jumps back to 1981

Dr Anthony Fauci talks to our host, Femi Oke, about how the emergence of this mysterious disease, later known as AIDS, changed the course of his career. He shares why an HIV vaccine, promised by 1986, is the “big and last Holy Grail that we have to achieve”.

We are also joined by:

-Physician Dr Michael Gottlieb, the first to report AIDS as a new disease in June 1981

-HIV activist and epidemiologist Dr Gregg Gonsalves on his role in galvanizing community activism

-Advocates Vincent Basajja (Uganda), Udom Likhitwonnawut (Thailand) and Maureen Luba(Malawi) dispelling myths about vaccines and vaccine research. (HIV unmuted, International AIDS Society, 17.05.2021, podcast, 24:00)

https://open.spotify.com/episode/0rQ5Hn9LpPucxxLYSqh25I?si=tfJz5fG7R-OgRJxWCEtNFw&nd=1

Time to Treatment Initiation and Retrospective Analysis of Antiretroviral Therapy Outcomes among HIV-positive Methadone Maintenance Therapy Clients in Primary Health-care Centers, Kuantan, Pahang. 

Ramlan AR, Mohamed Nazar NI, Tumian A, Ab Rahman NS, Mohamad D, Abdul Talib MS, Zakaria KFM, Izuddin MA, Zainal Abidin NA, T Syed Manso SS, Wan Hassan WNK. 

J Pharm Bioallied Sci. 2020 Nov;12(Suppl 2):S810-S815. doi: 10.4103/jpbs.JPBS_3_20. Epub 2020 Nov 5. PMID: 33828381; PMCID: PMC8021067.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021067/

HIV-Related Stigma Research as a Priority at the National Institutes of Health. 

Greenwood GL, Wilson A, Bansal GP, Barnhart C, Barr E, Berzon R, Boyce CA, Elwood W, Gamble-George J, Glenshaw M, Henry R, Iida H, Jenkins RA, Lee S, Malekzadeh A, Morris K, Perrin P, Rice E, Sufian M, Weatherspoon D, Whitaker M, Williams M, Zwerski S, Gaist P. 

AIDS Behav. 2021 Apr 22:1–22. doi: 10.1007/s10461-021-03260-6. Epub ahead of print. PMID: 33886010; PMCID: PMC8060687.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060687/

Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis. 

Ssentongo, P., Heilbrunn, E.S., Ssentongo, A.E. et al.

Sci Rep 11, 6283 (2021). doi.org/10.1038/s41598-021-85359-3

https://www.nature.com/articles/s41598-021-85359-3

Metaanalyse: COVID-19 bei HIV-Infizierten häufiger tödlich

Hershey/Pennsylvania – Menschen mit einer HIV-Infektion haben möglicherweise ein leicht erhöhtes Risiko, sich mit SARS-CoV-2 zu infizieren und bei einer Erkrankung an COVID-19 zu sterben. Zu diesem Ergebnis kommt eine Metaanalyse in Scientific Reports (2021; DOI: 10.1038/s41598-021-85359-3). (aerzteblatt.de, 14.05.2021)

https://www.aerzteblatt.de/nachrichten/123833/Metaanalyse-COVID-19-bei-HIV-Infizierten-haeufiger-toedlich

HIV incidence and associated risk factors in female spouses of men who inject drugs in Pakistan. 

Iversen, J., ul H Qureshi, S., Zafar, M. et al. 

Harm Reduct J 18, 51 (2021). doi.org/10.1186/s12954-021-00497-1

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-021-00497-1

Die langwirksame Injektionsbehandlung der HIV-Infektion ist ab 1. Mai 2021 verfügbar. 

Nach einer einmonatigen Einleitungsphase mit Tabletten erfolgt die erste und zweite Injektion im Abstand von vier Wochen. Dann müssen die beiden Medikamente Rekambys® und Vocabria® nur noch alle 8 Wochen gespritzt werden. (HIV&more, 23.05.2021)

https://www.hivandmore.de/aktuell/2021-04/spritzen-therapie.shtml

Findings among Indigenous participants of the Tracks survey of people who inject drugs in Canada, Phase 4, 2017-2019. 

Tarasuk J, Sullivan M, Bush D, Hui C, Morris M, Starlight T, Cholette F, Jonah L, Bryson M, Paquette D, Masching R. 

Can Commun Dis Rep. 2021 Jan 29;47(1):37-46. doi: 10.14745/ccdr.v47i01a07. PMID: 33679247; PMCID: PMC7919774.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919774/

The effect of needle and syringe program and opioid agonist therapy on the risk of HIV, hepatitis B and C virus infection for people who inject drugs in Amsterdam, the Netherlands: findings from an emulated target trial. 

van Santen, D. K., Anders, B., Matser, A., Maher, L., Hickman, M., Lodi, S., and Prins, M. (2021) Addiction, doi.org/10.1111/add.15503. 

Abstract

https://onlinelibrary.wiley.com/doi/abs/10.1111/add.15503

Deutsche AIDS-Hilfe. Informationen zu HIV für medizinisches Personal (Video)

Sie arbeiten in einer Praxis oder in einem Krankenhaus? Der Film gibt aktuelle Informationen rund um HIV, damit Sie Ihre Patient*innen gut und vertrauensvoll behandeln können. (DAH, 22.03.2021, Video, 02:14)

https://www.youtube.com/watch?v=lK3j2IknSjw

Video-Counseling Intervention to Address HIV Care Engagement, Mental Health, and Substance Use Challenges: A Pilot Randomized Clinical Trial for Youth and Young Adults Living with HIV. 

Saberi P, McCuistian C, Agnew E, Wootton AR, Legnitto Packard DA, Dawson-Rose C, Johnson MO, Gruber VA, Neilands TB. 

Telemed Rep. 2021 Jan 7;2(1):14-25. doi: 10.1089/tmr.2020.0014. PMID: 33575683; PMCID: PMC7869821.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869821/

Design and implementation of a prospective cohort study of persons living with and without HIV infection who are initiating medication treatment for opioid use disorder.

Biondi BE, Mohanty S, Wyk BV, Montgomery RR, Shaw AC, Springer SA. 

Contemp Clin Trials Commun. 2021 Jan 6;21:100704. doi: 10.1016/j.conctc.2021.100704. PMID: 33490708; PMCID: PMC7807244.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807244/

Peer driven or driven peers? A rapid review of peer involvement of people who use drugs in HIV and harm reduction services in low- and middle-income countries. 

Chang, J., Shelly, S., Busz, M. et al. Peer 

Harm Reduct J18, 15 (2021). doi.org/10.1186/s12954-021-00461-z

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-021-00461-z

Association between opioid agonist therapy use and HIV testing uptake among people who have recently injected drugs: a systematic review and meta‐analysis. 

Ferraro, C. F., Stewart, D. E., Grebely, J., Tran, L. T., Zhou, S., Puca, C., Hajarizadeh, B., Larney, S., Santo, T., Higgins, J. P. T.,Vickerman, P., Degenhardt, L., Hickman, M., and French, C. E. (2021) 

Addiction, doi.org/10.1111/add.15316. 

https://onlinelibrary.wiley.com/doi/full/10.1111/add.15316

The opioid crisis and HIV in the USA: deadly synergies

Hodder, Sally L et al.

The Lancet, Volume 0, Issue 0 

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00391-3/fulltext

Incidence of HIV and HCV in people who inject drugs: a systematic and meta-analysis review protocol. 

Sharhani A, Jorjoran Shushtari Z, Rahmani A, Armoon B, Noroozi M, Ahounbar E, Karimi SE, Higgs P. 

BMJ Open. 2021 Jan 15;11(1):e041482. doi: 10.1136/bmjopen-2020-041482. PMID: 33452193; PMCID: PMC7813328.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813328/

Hepatitis C (HCV) therapy for HCV mono-infected and HIV-HCV co-infected individuals living in Nepal. 

Kc S, Murphy H, Dixit S, Rai A, Pradhan B, Lagrange-Xelot M, Karki N, Dureault A, Karmacharya U, Panthi S, Tulachan N, Kc P, Kc A, Rajbhandari R, Trotter AB, Gölz J, Pradat P, Trépo C, Creac'H P. 

PLoS Negl Trop Dis. 2020 Dec 16;14(12):e0008931. doi: 10.1371/journal.pntd.0008931. PMID: 33326423.

https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0008931

Is it time for injectable antiretroviral therapy for HIV?

Hoy, Jennifer et al.

The Lancet, Volume 396, Issue 10267, 1944 - 1946 

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32231-5/fulltext

"I think everybody should take it if they're doing drugs, doing heroin, or having sex for money": a qualitative study exploring perceptions of pre-exposure prophylaxis among female participants in an opioid intervention court program. 

Przybyla SM, Cerulli C, Bleasdale J, Wilson K, Hordes M, El-Bassel N, Morse DS. 

Subst Abuse Treat Prev Policy. 2020 Nov 23;15(1):89. doi: 10.1186/s13011-020-00331-0. PMID: 33228721; PMCID: PMC7684895.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684895/

The last Black man with HIV in San Francisco: the potential role of gentrification on HIV getting to zero achievements

Pagkas-Bather, Jade et al.

The Lancet HIV, Volume 7, Issue 12, e853 - e856

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30250-2/fulltext

Multi-stakeholder consensus on a target product profile for an HIV cure

Lewin, Sharon R et al.

The Lancet HIV, Volume 0, Issue 0 

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30234-4/fulltext

Nora's Blog: On World AIDS Day, Celebrating Scientific Advances and Confronting the Complexities of HIV and Substance Use 

HIV is inextricably entwined with substance use. This fact is central to the development of new tools to prevent and treat HIV and the implementation science that informs how these tools can be successfully deployed in diverse communities around the world. (Nora Volkow, NIDA, 30.11.2020)

https://www.drugabuse.gov/about-nida/noras-blog/2020/11/world-aids-day-celebrating-scientific-advances-confronting-complexities-hiv-substance-use

Informationen zu HIV für die medizinische Praxis

Herausgeberinnen: Deutsche Aidshilfe e. V. und Bundesärztekammer, Berlin 2020

https://www.bundesaerztekammer.de/fileadmin/user_upload/downloads/pdf-Ordner/Patienten/Informationen_zu_HIV_fuer_die_medizinische_Praxis_2020_11_24_FINAL.pdf

Ärzteschaft. Broschüre soll Unsicherheiten im Umgang mit HIV-Patienten ausräumen

Berlin – Bundesärztekammer (BÄK) und Deutsche Aidshilfe (DAH) haben anlässlich des Welt-Aids-Tages am 1. Dezember eine gemeinsame Broschüre für Ärzte sowie medizini­sches Fachpersonal vorgelegt.

Sie soll Unsicherheiten im Umgang mit HIV-Patienten ausräumen und bietet neben Daten und Fakten zu HIV wichtige Hilfestellungen unter anderem zu Beratung und Aufklärung bei der HIV-Prophylaxe, der HIV-Testung und zum Umgang mit einem positiven Testergebnis. (aerzteblatt.de, 30.11.2020)

https://www.aerzteblatt.de/nachrichten/118862/Broschuere-soll-Unsicherheiten-im-Umgang-mit-HIV-Patienten-ausraeumen