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Pregabalin Misuse and Abuse in Jordan: a Qualitative Study of User Experiences.

Al-Husseini A, Wazaify M, Van Hout MC.

Int J Ment Health Addict. 2018;16(3):642-654. doi: 10.1007/s11469-017-9813-4. Epub 2017 Sep 15.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986847/

On the addictive power of gabapentinoids: a mini-review.

Bonnet U, Richter EL, Isbruch K, Scherbaum N.

Psychiatr Danub. 2018 Jun;30(2):142-149. doi: 10.24869/psyd.2018.142.

http://www.hdbp.org/psychiatria_danubina/pdf/dnb_vol30_no2/dnb_vol30_no2_142.pdf

Utilization of gabapentin by people in treatment for substance use disorders in Belgium (2011-2014): a cross-sectional study.

Van Baelen L, De Ridder K, Antoine J, Gremeaux L.

Arch Public Health. 2018 Mar 19;76:17. doi: 10.1186/s13690-018-0254-8.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858131/

Concomitant drug abuse of opioid dependent patients in maintenance treatment detected with a multi-target screening of oral fluid.

Wagner E, Raabe F, Martin G, Winter C, Plörer D, Krause DL, Adorjan K, Koller G, Pogarell O.

Am J Addict. 2018 May 24. doi: 10.1111/ajad.12737.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29797622

USA. Doctors sound the alarm on "opioid alternative" gabapentin

LOUISVILLE, Ky. -- A drug that has been touted as a safe alternative to opioid painkillers is now on the radar of health officials and law enforcement officials as it is being found in more and more overdose death. Gabapentin is a nerve pain medication that is typically used to treat seizures and pain associated with shingles. But amid the opioi epidemic that has ripped through the country, doctors have been prescribing it for a growing number of conditions in an attempt to find new ways to offer pain relief to patients -- and more people appear to be abusing it. (CBS, USA, 02.04.2018)

https://www.cbsnews.com/news/gabapentin-opioid-alternative-doctors-warning-about-drug/

Effect of preoperative gabapentin and acetaminophen on opioid consumption in video-assisted thoracoscopic surgery: a retrospective study.

Qiu R, Perrino AC Jr, Zurich H, Sukumar N, Dai F, Popescu W.

Rom J Anaesth Intensive Care. 2018 Apr;25(1):43-48. doi: 10.21454/rjaic.7518.251.gab.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931182/

Warum das Suchtpotenzial von Lyrica unterschätzt wird

Osnabrück. Die Schmerzmittel Lyrica und Oxycodon haben hohes Suchtpotenzial und sind offenbar in der Osnabrücker Drogenszene leicht zu bekommen. In den USA hat Präsident Donald Trump wegen der Opiodepidemie bereits den Gesundheitsnotstand erklärt. Was macht die Medikamente so gefährlich? Das erklärt Peter Flüchter, Chefarzt des Suchtmedizinischen Zentrums des Ameos-Klinikums Osnabrück. (Neue Osnabrücker Zeitung, 10.03.2018)

https://www.noz.de/lokales/osnabrueck/artikel/1030880/warum-das-suchtpotenzial-von-lyrica-unterschaetzt-wird#gallery&0&0&1030880


Pregabalin misuse in methadone maintenance treatment patients in Israel: Prevalence and risk factors.

Sason A, Adelson M, Schreiber S, Peles E.

Drug Alcohol Depend. 2018 May 29;189:8-11. doi: 10.1016/j.drugalcdep.2018.04.025.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29857329

Rausch auf Rezept Nach Tod ihres Verlobten: Osnabrückerin warnt vor Lyrica und „Oxys“

Osnabrück. Eigentlich lief es für F. aus Osnabrück nach vielen Jahren Drogenabhängigkeit ganz gut mit dem Methadonprogramm. Doch dann begann er, Tabletten zu nehmen – Lyrica und Oxycodon. Diese Woche wurde F. beerdigt. Seine Verlobte sagt: F. ist nicht der Erste aus der Szene rund um den Raiffeisenplatz, der in diesem Jahr in Folge von Schmerzmittelmissbrauch gestorben ist. (Neue Osnabrücker Zeitung, 10.03.2018)

https://www.noz.de/lokales/osnabrueck/artikel/1030986/nach-tod-ihres-verlobten-osnabrueckerin-warnt-vor-lyrica-und-oxys-1

Willis-Ekbom disease/restless legs syndrome in patients with opioid withdrawal.

Gupta R, Ali R, Ray R.

Sleep Med. 2018 May;45:39-43. doi: 10.1016/j.sleep.2017.09.028. 

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29680426

Pregabalin-induced first degree atrioventricular block in a young patient treated for pain from extrapulmonary tuberculosis.

Schiavo A, Stagnaro FM, Salzano A, Marra AM, Bobbio E, Valente P, Grassi S, Miniero M, Arcopinto M, Matarazzo M, Napoli R, Cittadini A.

Monaldi Arch Chest Dis. 2017 Sep 28;87(3):838. doi: 10.4081/monaldi.2017.838.

http://monaldi-archives.org/index.php/macd/article/view/838

Gabapentin (Neurontin).

Yasaei R, Saadabadi A.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-.
2018 Mar 16.

https://www.ncbi.nlm.nih.gov/books/NBK493228/

Use of preoperative gabapentin significantly reduces postoperative opioid consumption: a meta-analysis.

Arumugam S, Lau CS, Chamberlain RS.

J Pain Res. 2016 Sep 12;9:631-40. doi: 10.2147/JPR.S112626.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026214/

Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1.

Singh N, Ecker GF.

Int J Mol Sci. 2018 Apr 24;19(5). pii: E1278. doi: 10.3390/ijms19051278. Review.

http://www.mdpi.com/1422-0067/19/5/1278

Substance misuse of gabapentin.

Smith BH, Higgins C, Baldacchino A, Kidd B, Bannister J.

The British Journal of General Practice. 2012;62(601):406-407. doi:10.3399/bjgp12X653516.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404313/

Opioids and Gabapentin: A Potentially Dangerous Mixture

(Janaburson’s Blog, USA, 10.04.2018)

https://janaburson.wordpress.com/2018/04/10/opioids-and-gabapentin-a-potentially-dangerous-mixture/

Trial of tramadol plus gabapentin for opioid detoxification.

Ziaaddini H, Ziaaddini A, Asghari N, Nakhaee N, Eslami M.

Iran Red Crescent Med J. 2014 Dec 29;17(1):e18202. doi: 10.5812/ircmj.18202.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341495/

MEDIKAMENTENABHÄNGIGKEIT.Osnabrücker Arzt über Fluch und Segen von Lyrica und Cannabis

Osnabrück. Medikamentenabhängigkeit: Osnabrück. Wann ist ein Patient abhängig und warum werden im Osnabrücker Schmerzzentrum Pillen gezählt? Im Gespräch mit unserer Redaktion erklärt Dr. Carsten Brau die Hintergründe und verrät, wie er ein Jahr nach der Einführung des Cannabisgesetzes zum „Kiffen auf Rezept“ steht. Osnabrücker Arzt über Fluch und Segen von Lyrica und Cannabis. (NOZ – Neue Osnabrücker Zeitung, 18.04.2018)

https://www.noz.de/lokales/osnabrueck/artikel/1193513/osnabruecker-arzt-ueber-fluch-und-segen-von-lyrica-und-cannabis-1#gallery&0&0&1193513

USA. Amid Opioid Crisis, Cities Face Gabapentin, Too

Doctors are prescribing gabapentin more often because of its non-addictive properties, but law enforcement and drug rehabilitation programs are finding signs of abuse that exacerbate opioid abuse.

As the battle against opioid addiction continues across the country, many U.S. cities may overlook both a catalyst and its own budding crisis: the prescription nerve medication gabapentin, also known as ‘Johnnys’. (efficientgov.com, 13.02.2018)

https://efficientgov.com/blog/2018/02/13/amid-opioid-crisis-cities-face-gabapentin-too/

Pregabalin dispensing patterns in Amman-Jordan: An observational study from community pharmacies.

Al-Husseini A, Abu-Farha R, Wazaify M, Van Hout MC.

Saudi Pharm J. 2018 Mar;26(3):306-310. doi: 10.1016/j.jsps.2018.01.012.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856951/

Treatment of Generalized Anxiety Disorder with Gabapentin.

Markota M, Morgan RJ.

Case Rep Psychiatry. 2017;2017:6045017. doi: 10.1155/2017/6045017.

https://www.hindawi.com/journals/crips/2017/6045017/

Reversible Thrombocytopenia after Gabapentin in an HIV-Positive Patient.

Basith M, Francis A, Bellon A.

Case Rep Psychiatry. 2018 Jan 4;2018:5927065. doi: 10.1155/2018/5927065.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817358/

Pregabalin as adjunctive therapy in benzodiazepine discontinuation.

Caniff K, Telega E, Bostwick JR, Gardner KN.

Am J Health Syst Pharm. 2018 Jan 15;75(2):67-71. doi: 10.2146/ajhp160712.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29317396

Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study.

Fleet JL, Dixon SN, Kuwornu PJ, Dev VK, Montero-Odasso M, Burneo J, et al. (2018)

PLoS ONE 13(3): e0193134. doi.org/10.1371/journal.pone.0193134

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193134

Pregabalin.

Cross AL, Sherman Al.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2017 Jun-.
2017 Dec 5.

https://www.ncbi.nlm.nih.gov/books/NBK470341/

Prevalence of gabapentin in drug overdose postmortem toxicology testing results.

Slavova S, Miller A, Bunn TL, White JR, Kirschke D, Light T, Christy D, Thompson G, Winecker R.

Drug Alcohol Depend. 2018 Mar 10;186:80-85. doi: 10.1016/j.drugalcdep.2018.01.018.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29554591