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Fentanyl depression of respiration: comparison with heroin and morphine.

Hill R, Santhakumar R, Dewey W, Kelly E, Henderson G.

Br J Pharmacol. 2019 Sep 9. doi: 10.1111/bph.14860. 

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/31499594

Identification of a novel fentanyl analogue: p-hydroxy-butyrylfentanyl.

Oldenhof S, Ten Pierick A, Bruinsma J, Eustace S, Hulshof J, van den Berg J, Hoitink M.

Drug Test Anal. 2019 Sep 13. doi: 10.1002/dta.2695. 

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/31518047

Physiology, Opioid Receptor

Dhaliwal A, Gupta M.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Aug 29.

PMID: 31536249

https://www.ncbi.nlm.nih.gov/books/NBK546642/

Use of Kratom, an Opioid-like Traditional Herb, in Pregnancy.

Smid MC, Charles JE, Gordon AJ, Wright TE.

Obstet Gynecol. 2018 Oct;132(4):926-928. doi: 10.1097/AOG.0000000000002871.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30204686

Opioids and their endocrine effects: A systematic review and meta-analysis.

de Vries F, Bruin M, Lobatto DJ, Dekkers OM, Schoones JW, van Furth WR, Pereira AM, Karavitaki N, Biermasz NR, Zamanipoor Najafabadi AH.

J Clin Endocrinol Metab. 2019 Sep 12. pii: dgz022. doi: 10.1210/clinem/dgz022.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/31511863

Preference for drugs containing fentanyl from a cross-sectional survey of people who use illicit opioids in three United States cities

Kenneth B.Morales, Ju NyeongPark, Jennifer L.Glick, SabaRouhani, Traci C.Green, Susan G.Sherman

Drug and Alcohol Dependence, Volume 204, 1 November 2019, doi.org/10.1016/j.drugalcdep.2019.107547

https://www.sciencedirect.com/science/article/pii/S0376871619303163

Fentanyl auf Europareise

In manchen Nachbarländern sind synthetische Opioide bereits gefragter als Heroin. Wird Fentanyl bald die neue deutsche Welle auf dem Drogenmarkt? (doccheck.com, 25.09.2019)

https://www.doccheck.com/de/detail/articles/23208-fentanyl-auf-europareise

Diskussion. Schlusswort - In Reply (zu dem Beitrag Schätzung der Anzahl von Personen mit einer Opioidabhängigkeit)

Kraus, Ludwig

Dtsch Arztebl Int 2019; 116: 459; DOI: 10.3238/arztebl.2019.0459b

zu dem Beitrag Schätzung der Anzahl von Personen mit einer Opioidabhängigkeit von Prof. Dr. phil. Ludwig Kraus, Dr. phil. Nicki-Nils Seitz, Dr. rer. medic. Bernd Schulte, Dr. med. Peter Cremer-Schaeffer, Dr. phil. Barbara Braun, PD Dr. phil. Uwe Verthein, Dr. hum. biol. Tim Pfeiffer-Gerschel in Heft 9/2019

https://www.aerzteblatt.de/archiv/208457/Schlusswort

Diskussion: Auch bei uns Süchtige - Number ofAddicts Underestimated (zu dem Beitrag Schätzung der Anzahl von Personen mit einer Opioidabhängigkeit)

Abholz, Heinz-Harald

Dtsch Arztebl Int 2019; 116: 459; DOI: 10.3238/arztebl.2019.0459a

zu dem Beitrag Schätzung der Anzahl von Personen mit einer Opioidabhängigkeit von Prof. Dr. phil. Ludwig Kraus, Dr. phil. Nicki-Nils Seitz, Dr. rer. medic. Bernd Schulte, Dr. med. Peter Cremer-Schaeffer, Dr. phil. Barbara Braun, PD Dr. phil. Uwe Verthein, Dr. hum. biol. Tim Pfeiffer-Gerschel in Heft 9/2019

https://www.aerzteblatt.de/archiv/208456/Auch-bei-uns-Suechtige

Prescribing trends of gabapentin, pregabalin, and oxycodone: a secondary analysis of primary care prescribing patterns in England

Katlyn Green, Nora Cooke O'Dowd, Hilary Watt, Azeem Majeed, Richard J Pinder

BJGP bjgpopen.org/content/early/2019/09/16/bjgpopen19X101662 Open 17 September 2019; bjgpopen19X101662. DOI: 10.3399/bjgpopen19X101662

https://bjgpopen.org/content/early/2019/09/16/bjgpopen19X101662

Opioid-Epidemie: Panikmache in Deutschland

Die Zahl an Opioid-Erstverschreibungen nimmt in Deutschland zu. Ist das ein Grund, alarmiert zu sein? Wir vergleichen die Situation in Deutschland mit der in den USA. (DocCheck, 06.09.2019)

https://www.doccheck.com/de/detail/articles/23217-opioid-epidemie-panikmache-in-deutschland

Opioid Prescribing After Surgery in the United States, Canada, and Sweden.

Ladha KS, Neuman MD, Broms G, et al. 

JAMA Netw Open.Published online September 04, 20192(9):e1910734. doi:10.1001/jamanetworkopen.2019.10734

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2749239

Trends in use and misuse of opioids in the Netherlands: a retrospective, multi-source database study.

Kalkman GA, Kramers C, van Dongen RT, van den Brink W, Schellekens A.

Lancet Public Health. 2019 Aug 20. pii: 

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(19)30128-8/fulltext

The Kappa Opioid Receptor Is Associated With Naltrexone-Induced Reduction of Drinking and Craving.

de Laat B, Goldberg A, Shi J, Tetrault JM, Nabulsi N, Zheng MQ, Najafzadeh S, Gao H, Kapinos M, Ropchan J, O'Malley SS, Huang Y, Morris ED, Krishnan-Sarin S.

Biol Psychiatry. 2019 Jun 8. pii: S0006-3223(19)31413-1. doi: 10.1016/j.biopsych.2019.05.021. 

https://www.biologicalpsychiatryjournal.com/article/S0006-3223(19)31413-1/fulltext

Opioid prescription patterns in Germany and the global opioid epidemic: Systematic review of available evidence.

Rosner B, Neicun J, Yang JC, Roman-Urrestarazu A (2019) 

PLoS ONE 14(8): e0221153. doi.org/10.1371/journal.pone.0221153

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221153

Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids.

Makunts T, U A, Atayee RS, Abagyan R.

Sci Rep. 2019 Aug 28;9(1):12490. doi: 10.1038/s41598-019-48955-y.

https://www.nature.com/articles/s41598-019-48955-y

Tramadol könnte Hypoglykämien auslösen

San Diego – Das Schmerzmittel Tramadol, das zunehmend als sichere Alternative zu anderen Opioiden betrachtet wird, kann offenbar schwere Hypoglykämien auslösen. Dies kam in einer Analyse von Datenbanken der US-Arzneimittelbehörde FDA in Scientific Reports(2019; 9: 12490) heraus. (aerzteblatt.de, 29.08.2019)

https://www.aerzteblatt.de/nachrichten/105626/Tramadol-koennte-Hypoglykaemien-ausloesen

Opioid Prescription Patterns and Risk Factors Associated With Opioid Use in the Netherlands.

Bedene A, Lijfering WM, Niesters M, et al. 

JAMA Netw Open.Published online August 28, 20192(8):e1910223. doi:10.1001/jamanetworkopen.2019.10223

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2749053

The Future of Fentanyl and Other Synthetic Opioids.

Pardo, Bryce, Jirka Taylor, Jonathan P. Caulkins, Beau Kilmer, Peter Reuter, and Bradley D. Stein

Santa Monica, CA: RAND Corporation, 2019. 

https://www.rand.org/pubs/research_reports/RR3117.html

 

The Emergence of "Coachella" Heroin in the Midwest.

Sethi R, Luvisi J, Ahonen K, Irwin T.

Prim Care Companion CNS Disord. 2019 Jul 18;21(4). pii: 18l02394. doi: 10.4088/PCC.18l02394.

https://www.psychiatrist.com/pcc/article/Pages/2019/v21n04/18l02394.aspx

Novel synthetic opioids - toxicological aspects and analysis.

Tabarra I, Soares S, Rosado T, Gonçalves J, Luís Â, Malaca S, Barroso M, Keller T, Restolho J, Gallardo E.

Forensic Sci Res. 2019 Jul 3;4(2):111-140. doi: 10.1080/20961790.2019.1588933. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609355/

A chemically contiguous hapten approach for a heroin-fentanyl vaccine.

Natori Y, Hwang CS, Lin L, Smith LC, Zhou B, Janda KD.

Beilstein J Org Chem. 2019 May 3;15:1020-1031. doi: 10.3762/bjoc.15.100.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541359/

Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids.

Olson KM, Duron DI, Womer D, Fell R, Streicher JM (2019) 

PLoS ONE 14(6): e0217371. doi.org/10.1371/journal.pone.0217371

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217371

Australien. Weekly Dose: Krokodil, the Russian ‘flesh-eating’ drug, makes a rare appearance in Australia

A young man recently turned up at a rural drug and alcohol service in New South Wales seeking help because of an infection in his arm. He said he had injected the drug Krokodil, which had not previously been reported in Australia. (The Conversation, Australien, 19.06.2019)

https://theconversation.com/weekly-dose-krokodil-the-russian-flesh-eating-drug-makes-a-rare-appearance-in-australia-117594

Tapentadol use among people who regularly inject drugs in Australia

Sutherland,R., Memedovic,S., Degenhardt,L., Farrell,M.,& Peacock,A. (2019).

DrugTrendsBulletinSeries.Sydney:NationalDrugandAlcoholResearchCentre,UniversityofNewSouthWalesSydney. 

Tapentadol is a centrally acting opioid analgesic registered for use in Australia to treat moderate to severe pain. A recent review has suggested a lack of data regarding ‘abuse, dependence, diversion, or recreational use’ of tapentadol. This paper addresses this research gap by examining patterns of tapentadol use among a sentinel sample of people who regularly inject drugs in Australia.

https://ndarc.med.unsw.edu.au/sites/default/files/ndarc/resources/IDRS%20Tapentadol%20Bulletin_FINAL.pdf

Rate of Fentanyl Positivity Among Urine Drug Test Results Positive for Cocaine or Methamphetamine.

LaRue L, Twillman RK, Dawson E, et al. 

JAMA Netw Open.2019;2(4):e192851. doi:10.1001/jamanetworkopen.2019.2851

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2731684

A Promising Alternative to Opioid Pain Medications. 

NIDA. (2019, February 12). 

https://www.drugabuse.gov/news-events/nida-notes/2019/02/promising-alternative-to-opioid-pain-medications

Chronic use of tramadol after acute pain episode: cohort study 

Thiels Cornelius A, Habermann Elizabeth B, Hooten W Michael, Jeffery Molly M. 

BMJ 2019; 365 :l1849 

https://www.bmj.com/content/365/bmj.l1849

US-Studie sieht Abhängigkeitspotenzial bei Tramadol

Rochester – (...) Die Autoren einer Studie im Britischen Ärzteblatt(BMJ2019; 365: l1849) vermuten (..), dass das Abhängigkeitspotenzial von Tramadol unterschätzt wird. (aerzteblatt.de, 15.05.2019)

https://www.aerzteblatt.de/nachrichten/103118/US-Studie-sieht-Abhaengigkeitspotenzial-bei-Tramadol

Opioids in the immune system: from experimental studies to clinical practice.

Moyano J, Aguirre L.

Rev Assoc Med Bras (1992). 2019 Feb;65(2):262-269. doi: 10.1590/1806-9282.65.2.262. Review.

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302019000200262