Chronic tramadol abuse as a cause of serotonin syndrome.  van Gemert RLA, Wansink L, Gresnigt FMJ.  Toxicol Rep. 2026 Mar 9;16:102237. doi: 10.1016/j.toxrep.2026.102237. PMID: 41853658; PMCID: PMC12994067. https://pmc.ncbi.nlm.nih.gov/a…

A µ-opioid receptor superagonist analgesic with minimal adverse effects.  Gomez, J.L., Ventriglia, E.N., Frangos, Z.J. et al. Nature (2026). doi.org/10.1038/s41586-026-10299-9 https://www.nature.com/articles/s41586-026-10299-9

Synthetische Opioide - TRENDSPOTTER-UPDATE Dr. Heiko Bergmann, Dr. Franziska Schneider, Anna-Mavie Beil, Magdalena Janz & Esther Neumeier IFT Institut für Therapieforschung, März 2026 https://mindzone.info/wp-content/uploads/2026/03/NEWS-Tren…

UNODC. February 2026 - Increasing nitazene and orphine analogues (synthetic opioids) and the implications for the use of test strips VIENNA, Austria – 25 February 2026: Nitazenes are a class of potent synthetic opioids comprising multiple structura…

A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses?  Mammoliti E, Nielsen S, Roxburgh A.  Drug Alcohol Rev. 2026 Jan;45(1):e14079. doi: 10.1111/d…

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024.  Zhu DT, Fitzgerald ND, Palamar JJ, Krotulski AJ.  Addiction. 2026. doi.org/10.1111/add.70378…