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12 Americans Die of an Overdose Every Hour. We Have the Knowledge to Prevent That.

(New York Times, USA, 24.06.2022)


Increased risk of death immediately after discharge from compulsory care for substance abuse. 

Ledberg A, Reitan T. 

Drug Alcohol Depend. 2022 Jul 1;236:109492. doi: 10.1016/j.drugalcdep.2022.109492. Epub 2022 May 10. PMID: 35617775.


Long-term Risk of Overdose or Mental Health Crisis After Opioid Dose Tapering. 

Fenton JJ, Magnan E, Tseregounis IE, Xing G, Agnoli AL, Tancredi DJ. 

JAMA Netw Open. 2022;5(6):e2216726. doi:10.1001/jamanetworkopen.2022.16726


Analysis of Urine Drug Test Results From Substance Use Disorder Treatment Practices and Overdose Mortality Rates, 2013-2020. 

Whitley P, LaRue L, Fernandez SA, Passik SD, Dawson E, Jackson RD. 

JAMA Netw Open. 2022;5(6):e2215425. doi:10.1001/jamanetworkopen.2022.15425


Australien. New report finds five drug-induced deaths per day among Australians in 2020

There were 1,842 drug-induced deaths among Australians in 2020, according to preliminary estimates in a new report by the Drug Trends program at the National Drug and Alcohol Research Centre (NDARC), UNSW Sydney.

This is equivalent to five drug-induced deaths per day or 7.2 deaths per 100,000 Australians. (UNSW – University of South Wales, Sydney, 26.05.2022)


Adverse Childhood Experiences and Overdose: Lessons From Overdose Data to Action. 

Wisdom AC, Govindu M, Liu SJ, Meyers CM, Mellerson JL, Gervin DW, DePadilla L, Holland KM. 

Am J Prev Med. 2022 Jun;62(6S1):S40-S46. doi: 10.1016/j.amepre.2021.11.015. PMID: 35597582.


Analysis of Stimulant Prescriptions and Drug-Related Poisoning Risk Among Persons Receiving Buprenorphine Treatment for Opioid Use Disorder. 

Mintz CM, Xu KY, Presnall NJ, Hartz SM, Levin FR, Scherrer JF, Bierut LJ, Grucza RA. 

JAMA Netw Open. 2022 May 2;5(5):e2211634. doi: 10.1001/jamanetworkopen.2022.11634. PMID: 35544135; PMCID: PMC9096599.


Sex-based differences in the predisposing factors of overdose: A retrospective study. 

Tan ST, Lo CH, Liao CH, Su YJ. 

Biomed Rep. 2022 Jun;16(6):49. doi: 10.3892/br.2022.1532. Epub 2022 Apr 20. PMID: 35620313; PMCID: PMC9112373.


Substance Abuse and Mental Health Services Administration. (2022). Preliminary Findings from Drug-Related Emergency Department Visits, 2021

Drug Abuse Warning Network (HHS Publication No. PEP22-07-03-001). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. 


USA. Tracking the opioid overdose crisis. Have Black and White communities in America been affected the same?

Since the late 1990s, the United States has been experiencing an unprecedented overdose crisis driven primarily by opioids. Understanding how racial-ethnic groups may be differentially affected by this public health crisis is key to tailoring support and services. This study compared opioid overdose death rates between Black and White Americans from the beginning of the overdose crisis in 1999 to 2018. (RRI – Recovery Research Institute, USA, Mai 2022)


USA. Vital Strategies: Overdose Prevention

In the United States, the annual number of overdose deaths has surpassed firearm and car crash fatalities combined. 

The crisis of overdose is affecting US communities everywhere. Progress against the still rising rates will require leadership across levels of government, and from communities, providers, institutions, and advocates. Leadership must include people who use drugs.

We strive to promote innovation, improve quality, build scale, and ensure sustainability, grounded in data and evidence, and focused on racial equity. Our approach is multidisciplinary, inclusive, and responsive to local conditions.

As momentum grows for a health-based response to drug use, overdose has risen sharply in Black and Latinx communities. Progress must address the collateral consequences of drug use criminalization in communities of color. (Vital Trategies, USA, 2022)


Risk of Overdose Associated With Co-prescription of Antipsychotics and Opioids: A Population-Based Cohort Study. 

Szmulewicz AG, Bateman BT, Levin R, Huybrechts KF. 

Schizophr Bull. 2022 Mar 1;48(2):405-413. doi: 10.1093/schbul/sbab116. PMID: 34582543; PMCID: PMC8886580.


A low-barrier, flexible safe supply program to prevent deaths from overdose

Sukhpreet Klaire, Christy Sutherland, Thomas Kerr, Mary Clare Kennedy

CMAJ May 2022, 194 (19) E674-E676; DOI: 10.1503/cmaj.211515 


Scientists are developing patch that warns of oncoming drug overdose

With the United States facing an epidemic of drug overdoses, researchers are developing a wearable patch that can detect an oncoming opioid OD and deliver doses of a drug that could save lives. (Medscape, USA, 17.05.2022)


Australien. Five drug-induced deaths per day among Australians in 2020, report finds

The latest Drug Trends report from UNSW’s National Drug and Alcohol Research Centre shows more than 1800 drug-induced deaths in Australia in 2020.


Preliminary estimates indicate there were 1842 drug-induced deaths among Australians in 2020, equivalent to 1.1 percent of all reported deaths in Australia. This equates to 7.2 deaths per 100,000 Australians. (NDARC – University of New South Wales, Australien, 26.05.2022)


USA. Nearly 108,000 overdose deaths in 2021 bear out a prediction from five years ago forecasting the devastating toll

A grim prediction made half a decade ago by University of Pittsburgh School of Public Health epidemiologists and modelers has come true: More than 100,000 people are now dying from drug overdoses annually in the U.S. The milestone comes as the International Journal of Drug Policy publishes a special section of the June issue reflecting on the exponential growth in drug-related deaths the Pitt team uncovered in 2017. (University of Pittsburgh, USA, 25.05.2022)


USA. USA verzeichnen mehr Drogentote

Washington – Inmitten der Coronapandemie ist die Zahl der Drogentoten in den USA im vergangenen Jahr auf mehr als 100.000 gestiegen. Es seien 107.622 Menschen durch eine Drogenüberdosis gestorben, heißt es in einer gestern vorgelegten Statistik der Behörden. Die Zahl der Drogentoten nahm im Vergleich zum Vorjahr (2020) demnach um 15 Prozent zu. (aerzteblatt.de, 12.05.2022)


Rauschgift-Todesfälle 2021 nach Todesursachen

(Bundeskriminalamt Wiesbaden, 2022)


Variability in the unregulated opioid market in the context of extreme rates of overdose. 

Larnder A, Saatchi A, Borden SA, Moa B, Gill CG, Wallace B, Hore D. 

Drug Alcohol Depend. 2022 Mar 26;235:109427. doi: 10.1016/j.drugalcdep.2022.109427. Epub ahead of print. PMID: 35405459.


Supporting people responding to overdoses. 

Marks C, Wagner KD. 

Lancet Public Health. 2022 Mar;7(3):e198-e199. doi: 10.1016/S2468-2667(22)00011-1. Epub 2022 Feb 10. PMID: 35151373.


Evaluation of Opioid Overdose Reports in Patients Treated with Extended-Release Naltrexone: Postmarketing Data from 2006 to 2018. 

Jain P, McKinnell K, Marino R, Vunnava P, Liles-Burden MA, Desai A, Wenten M, Fratantonio J, Akerman SC, Sullivan MA, Bloomgren G. 

Drug Saf. 2021 Mar;44(3):351-359. doi: 10.1007/s40264-020-01020-4. Epub 2020 Nov 30. PMID: 33258068; PMCID: PMC7892734.


Unspecified opioids among opioid overdoses in Oslo, Norway. 

Iqbal ZZ, Nguyen TMT, Brekke M, Vallersnes OM. 

BMC Res Notes. 2022 Apr 9;15(1):134. doi: 10.1186/s13104-022-06022-2. PMID: 35397589; PMCID: PMC8994352.


Treatment of opioid overdose: current approaches and recent advances. 

Britch SC, Walsh SL. 

Psychopharmacology (Berl). 2022 Apr 7:1–19. doi: 10.1007/s00213-022-06125-5. Epub ahead of print. PMID: 35385972; PMCID: PMC8986509.


Association between discontinuing chronic opioid therapy and newly diagnosed substance use disorders, accidents, self-inflicted injuries and drug overdoses within the prescribers' health care system: a retrospective cohort study. 

Hayes CJ, Krebs EE, Li C, Brown J, Hudson T, Martin BC. 

Addiction. 2022 Apr;117(4):946-968. doi: 10.1111/add.15689. Epub 2021 Oct 25. PMID: 34514677; PMCID: PMC8904270.



Kanada. Nearly 1 in 3 employees to die from an opioid overdose works in construction. Is the industry doing enough to confront the crisis?

Amid a surge of fatal overdoses, Ontario’s construction industry is taking steps to raise awareness of the stark impact on the sector. (Toronto Star, Kanada, 04.05.2022)


Epidemiological trends in opioid-only and opioid/polysubstance-related death rates among American Indian/Alaska Native populations from 1999 to 2019: a retrospective longitudinal ecological study

Qeadan F, Madden EF, Mensah NA, et al

BMJ Open 2022;12:e053686. doi: 10.1136/bmjopen-2021-053686 


Treatment of overdose in the synthetic opioid era. 

Skolnick P. 

Pharmacol Ther. 2022 May;233:108019. doi: 10.1016/j.pharmthera.2021.108019. Epub 2021 Oct 9. PMID: 34637841.


Association of Opioid Dose Reduction With Opioid Overdose and Opioid Use Disorder Among Patients Receiving High-Dose, Long-term Opioid Therapy in North Carolina. 

DiPrete BL, Ranapurwala SI, Maierhofer CN, et al. 

JAMA Netw Open. 2022;5(4):e229191. doi:10.1001/jamanetworkopen.2022.9191


Trends in Mortality From Novel Psychoactive Substances as “Legal Highs”: Gender Differences in Manner of Death and Implications for Risk Differences for Women

Lucy Webb, Xin Shi, Christine Goodair and Survjit Cheeta

Front. Psychiatry, 21 April 2022, doi.org/10.3389/fpsyt.2022.890840


USA. Overdoses, not COVID-19, drive spike in LA homeless deaths

Nearly 2,000 homeless people died in Los Angeles County during the first year of the pandemic, an increase of 56% from the previous year, driven mainly by drug overdoses, authorities said. 

The findings released Friday in a report from the county's Department of Public Health showed that despite initial fears, the virus itself was not the main culprit in deaths among California's largest-in-the-nation unhoused population. But it did cut people off from mental health and substance abuse treatment after services were drastically reduced to prevent the spread of the virus. (MedXpress, USA, 24.04.2022)