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Predictors of Overdose Death Among High-Risk Emergency Department Patients With Substance-Related Encounters: A Data Linkage Cohort Study.

Krawczyk N, Eisenberg M, Schneider KE, et al. 

Ann Emerg Med. 2020;75(1):1‐12. doi:10.1016/j.annemergmed.2019.07.014

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928412/

Regional Differences in the Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2017. 

Hedegaard H, Bastian BA, Trinidad JP, Spencer MR, Warner M. 

Natl Vital Stat Rep. 2019;68(12):1‐16. 

https://www.cdc.gov/nchs/data/nvsr/nvsr68/nvsr68_12-508.pdf

Regional variation in states' naloxone accessibility laws in association with opioid overdose death rates-Observational study (STROBE compliant). 

You HS, Ha J, Kang CY, et al. 

Medicine (Baltimore). 2020;99(22):e20033. doi:10.1097/MD.0000000000020033

https://journals.lww.com/md-journal/FullText/2020/05290/Regional_variation_in_states__naloxone.18.aspx

Tackling the overdose crisis: The role of safe supply 

Ivsins A, Boyd J, Beletsky L, McNeil R. 

[published online ahead of print, 2020 May 1]. Int J Drug Policy. 2020;80:102769. doi:10.1016/j.drugpo.2020.102769

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252037/

Generational trends in US opioid-overdose deaths 

Deaths from opioid overdose in the USA have followed three distinct waves that have all affected baby boomers, generation X and millennials. Wayne Hall, Louisa Degenhardt and Matthew Hickman. (Nature Medicine, Published online 04. May 2020, doi.org/10.1038/s41591-020-0875-7

https://www.nature.com/articles/s41591-020-0875-7.epdf

Estimating the prevalence of problem drug use from drug‐related mortality data.

Jones, H. E., Harris, R. J., Downing, B. C., Pierce, M., Millar, T., Ades, A. E., Welton, N. J., Presanis, A. M., De Angelis, D., and Hickman, M. ( 2020) Addiction, doi.org/10.1111/add.15111. 

https://onlinelibrary.wiley.com/doi/abs/10.1111/add.15111

Kanada. More Canadians are dying of drug overdoses — and coronavirus is to blame

According to new data from across the country, opioid overdoses have increased since social distancing measures began in March due to the COVID-19 pandemic. In the wake of the outbreak, support programs have been more difficult to access by people suffering from opioid addiction. (Global News, Kanada, 28.05.2020)

https://globalnews.ca/news/6995586/canadians-dying-drug-overdoses-coronavirus

Fighting Fire with Fire: Development of Intranasal Nalmefene to Treat Synthetic Opioid Overdose.

Krieter P, Gyaw S, Crystal R, Skolnick P.

J Pharmacol Exp Ther. 2019 Nov;371(2):409-415. doi: 10.1124/jpet.118.256115. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863453/

Alcohol or Benzodiazepine Co-involvement With Opioid Overdose Deaths in the United States, 1999-2017.

Tori ME, Larochelle MR, Naimi TS.

JAMA Netw Open. 2020 Apr 1;3(4):e202361. doi: 10.1001/jamanetworkopen.2020.2361.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2764233

USA. The Opioid Crisis and the Black/African American Population: An Urgent Issue

Substance Abuse and Mental Health Services Administration: Publication No. PEP20-05-02-001. Office of Behavioral Health Equity. Substance Abuse and Mental Health Services Administration, 2020. 

This issue brief presents recent data on prevalence of opioid misuse and death rates in the Black/AA population; contextual factors & challenges to prevention & treatment; innovative outreach & engagement strategies to connect people to evidence-based treatment; and the importance of community voice. (SAMHSA, USA, März 2020)

https://store.samhsa.gov/sites/default/files/SAMHSA_Digital_Download/PEP20-05-02-001_508%20Final.pdf

Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study.

Pearce LA, Min JE, Piske M, Zhou H, Homayra F, Slaunwhite A, Irvine M, McGowan G, Nosyk B.

BMJ. 2020 Mar 31;368:m772. doi: 10.1136/bmj.m772.

https://www.bmj.com/content/368/bmj.m772.long

Alcohol or Benzodiazepine Co-involvement With Opioid Overdose Deaths in the United States, 1999-2017.

Tori ME, Larochelle MR, Naimi TS.

JAMA Netw Open. 2020 Apr 1;3(4):e202361. doi: 10.1001/jamanetworkopen.2020.2361.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146101/

Nonfatal Drug Overdoses Treated in Emergency Departments — United States, 2016–2017.

Vivolo-Kantor AM, Hoots BE, Scholl L, et al. 

MMWR Morb Mortal Wkly Rep 2020;69:371–376. doi.org/10.15585/mmwr.mm6913a3

https://www.cdc.gov/mmwr/volumes/69/wr/mm6913a3.htm

Combining opioids and benzodiazepines: effects on mortality and severe adverse respiratory events.

Boon M, van Dorp E, Broens S, Overdyk F.

Ann Palliat Med. 2020 Mar;9(2):542-557. doi: 10.21037/apm.2019.12.09. 

http://apm.amegroups.com/article/view/35734/29319

Do interruptions to the continuity of methadone maintenance treatment in specialist addiction settings increase the risk of drug‐related poisoning deaths? A retrospective cohort study.

Durand, L., O'Driscoll, D., Boland, F., Keenan, E., Ryan, B. K., Barry, J., Bennett, K., Fahey, T., and Cousins, G. (2020) 

Addiction, doi.org/10.1111/add.15004.

https://onlinelibrary.wiley.com/doi/full/10.1111/add.15004?campaign=wolearlyview

Delivering Opioid Overdose Prevention in Bars and Nightclubs

Allen, Bennett MA; Sisson, Laura BA; Dolatshahi, Jennifer MPA; Blachman-Forshay, Jaclyn MPH; Hurley, Ariel MPH, LMSSW; Paone, Denise EdD 

Journal of Public Health Management and Practice: May/June 2020 - Volume 26 - Issue 3 - p 232-235 doi: 10.1097/PHH.0000000000001014 

https://journals.lww.com/jphmp/Fulltext/2020/05000/Delivering_Opioid_Overdose_Prevention_in_Bars_and.6.aspx

Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study.

Pearce LA, Min JE, Piske M, Zhou H, Homayra F, Slaunwhite A, Irvine M, McGowan G, Nosyk B.

BMJ. 2020 Mar 31;368:m772. doi: 10.1136/bmj.m772.

https://www.bmj.com/content/368/bmj.m772.long

Addressing overdose risk among unstably housed women in San Francisco, California: an examination of potential fentanyl contamination of multiple substances.

Meacham MC, Lynch KL, Coffin PO, Wade A, Wheeler E, Riley ED.

Harm Reduct J. 2020 Mar 10;17(1):17. doi: 10.1186/s12954-020-00361-8.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063812/

Incidence and Lethality of Suicidal Overdoses by Drug Class.

Miller TR, Swedler DI, Lawrence BA, Ali B, Rockett IRH, Carlson NN, Leonardo J.

JAMA Netw Open. 2020 Mar 2;3(3):e200607. doi: 10.1001/jamanetworkopen.2020.0607.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090840/

Drug and Opioid-Involved Overdose Deaths - United States, 2017-2018.

Wilson N, Kariisa M, Seth P, Smith H 4th, Davis NL.

MMWR Morb Mortal Wkly Rep. 2020 Mar 20;69(11):290-297. doi: 10.15585/mmwr.mm6911a4.

https://www.cdc.gov/mmwr/volumes/69/wr/mm6911a4.htm

Association Between Opioid Dose Variability and Opioid Overdose Among Adults Prescribed Long-term Opioid Therapy.

Glanz JM, Binswanger IA, Shetterly SM, Narwaney KJ, Xu S.

JAMA Netw Open. 2019 Apr 5;2(4):e192613. doi: 10.1001/jamanetworkopen.2019.2613.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481879/

Deutschland. Drogenbeauftragte: 1.398 Menschen 2019 an illegalen Drogen gestorben

Drogenbeauftragte Daniela Ludwig: „Diese Zahlen können wir nicht hinnehmen! Wir brauchen flächendeckende Substitutions- und Hilfsangebote – auch in der Coronakrise“. (drogenbeauftragte.de, 23.03.2020)

https://www.drogenbeauftragte.de/presse/pressekontakt-und-mitteilungen/2020/i-quartal/1398-menschen-an-illegalen-drogen-gestorben.html

Notes from the Field: Opioid-Involved Overdose Deaths with Fentanyl or Fentanyl Analogs Detected — 28 States and the District of Columbia, July 2016–December 2018.

O’Donnell J, Gladden RM, Goldberger BA, Mattson CL, Kariisa M. 

MMWR Morb Mortal Wkly Rep 2020;69:271–273. doi.org/10.15585/mmwr.mm6910a4

https://www.cdc.gov/mmwr/volumes/69/wr/mm6910a4.htm

A New Generation of Drug Users in St. Petersburg, Russia? HIV, HCV, and Overdose Risks in a Mixed-Methods Pilot Study of Young Hard Drug Users.

Meylakhs P, Friedman SR, Meylakhs A, Mateu-Gelabert P, Ompad DC, Alieva A, Dmitrieva A.

AIDS Behav. 2019 Dec;23(12):3350-3365. doi: 10.1007/s10461-019-02489-6.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788941/

Zahl der wegen Alkoholmissbrauchs behandelten Minderjährigen leicht gesunken

Wiesbaden – Die Zahl der wegen akuten Alkoholmissbrauchs in Krankenhäusern behandelten Kinder und Jugendliche ist leicht gesunken. Das teilte das Statistische Bundesamt heute in Wiesbaden mit. Demnach wurden 2017 rund 14.900 Minderjährige zwischen zehn und 17 Jahren wegen übermäßigen Alkoholkonsums stationär aufgenommen. Das waren 1,6 Prozent weniger als 2016. (aerzteblatt.de, 18.02.2020)

https://www.aerzteblatt.de/nachrichten/109468/Zahl-der-wegen-Alkoholmissbrauchs-behandelten-Minderjaehrigen-leicht-gesunken

USA. 1 in 4 Opioid ODs Involves Kids and Teens

MONDAY, Feb. 17, 2020 (HealthDay News) -- More than a quarter of all opioid overdoses in the United States involve teenagers, and a full fifth of those cases were likely suicide attempts, new research shows.

The findings follow an in-depth analysis of nearly 754,000 American opioid poisoning cases that occurred between 2005 and 2018. All had been reported to the U.S. National Poison Data System. And almost 208,000 of those cases involved children 18 years old or younger.

During the 13-year study period, the pediatric overdose landscape has taken a turn for the worse, said study author Dr. Megan Land, a pediatric critical care fellow at Emory University's School of Medicine in Atlanta. )(Health Day, USA, 17.02.2020)

https://consumer.healthday.com/bone-and-joint-information-4/opioids-990/1-in-4-opioid-ods-involves-kids-and-teens-754893.html

Do interruptions to the continuity of methadone maintenance treatment in specialist addiction settings increase the risk of drug-related poisoning deaths? A retrospective-cohort study.

Durand L, O'Driscoll D, Boland F, Keenan E, Ryan B, Barry J, Bennett K, Fahey T, Cousins G.

Addiction. 2020 Feb 7. doi: 10.1111/add.15004. 

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/32034837

USA. The opioid crisis may be far worse than we thought: study

New research appearing in the journal Addiction shows that the number of deaths attributed to opioid-related overdoses could be 28 percent higher than reported due to incomplete death records. This discrepancy is more pronounced in several states, including Alabama, Mississippi, Pennsylvania, Louisiana, and Indiana, where the estimated number of deaths more than doubles—obscuring the scope of the opioid crisis and potentially affecting programs and funding intended to confront the epidemic. (University of Rochester Medical Center, USA, 27.02.2020)

https://medicalxpress.com/news/2020-02-opioid-crisis-worse-thought.html

USA. Teaching Children How to Reverse an Overdose

In rural Carter County, Tenn., health officials have embraced a strategy for stemming addiction: Teaching children as young as 6 how to administer Narcan, a nasal spray that can stop an opioid overdose from being fatal. (New York Times, 24.02.2020)

https://www.nytimes.com/2020/02/23/us/opioids-tennessee-narcan-training.html

Acute Care, Prescription Opioid Use, and Overdose Following Discontinuation of Long-Term Buprenorphine Treatment for Opioid Use Disorder.

Williams AR, Samples H, Crystal S, Olfson M.

Am J Psychiatry. 2020 Feb 1;177(2):117-124. doi: 10.1176/appi.ajp.2019.19060612. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002204/