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Drug Overdose Deaths Involving Cocaine and Psychostimulants with Abuse Potential — United States, 2003–2017.

USA. Kariisa M, Scholl L, Wilson N, Seth P, Hoots B. 

MMWR Morb Mortal Wkly Rep 2019;68:388–395. doi.org/10.15585/mmwr.mm6817a3

https://www.cdc.gov/mmwr/volumes/68/wr/mm6817a3.htm

Opioid overdose deaths and potentially inappropriate opioid prescribing practices (PIP): A spatial epidemiological study.

Stopka TJ, Amaravadi H, Kaplan AR, Hoh R, Bernson D, Chui KKH, Land T, Walley AY, LaRochelle MR, Rose AJ.

Int J Drug Policy. 2019 Apr 10;68:37-45. doi: 10.1016/j.drugpo.2019.03.024. 

https://www.sciencedirect.com/science/article/pii/S0955395919300908

Overdose Risk and Client Characteristics Associated With the Injection of Buprenorphine at a Medically Supervised Injecting Center in Sydney, Australia.

Power J, Salmon AM, Latimer J, Jauncey M, Day CA.

Subst Use Misuse. 2019 Apr 11:1-8. doi: 10.1080/10826084.2019.1600147. 

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30973286

USA. 'I don’t want to overdose and die:' one woman's death, one country's shame 

Saige Earley, who was found dead of a heroin overdose in a toilet stall at Syracuse airport, is the face of ‘real people’ devastated by the worst drug epidemic in American history. (The Guardian, UK, 29.04.2019)

https://www.theguardian.com/us-news/2019/apr/29/i-dont-want-to-overdose-and-die-one-womans-death-one-countrys-shame

Association Between Opioid Dose Variability and Opioid Overdose Among Adults Prescribed Long-term Opioid Therapy. Glanz JM, Binswanger IA, Shetterly SM, Narwaney KJ, Xu S. 

JAMA Netw Open.2019;2(4):e192613. doi:10.1001/jamanetworkopen.2019.2613

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2730786

STOP OVERDOSE NOW - Real-Time Overdose Prevention Networks 

SON – Stop Overdose Now! (April 2019)

https://stopoverdosenow.org/

How the complex pharmacology of the fentanyls contributes to their lethality.

Gill, H., Kelly, E., and Henderson, G. ( 2019) 

Addiction, doi.org/10.1111/add.14614.

https://onlinelibrary.wiley.com/doi/10.1111/add.14614

EMCDDA. An analysis of post-mortem toxicology practices in drug-related death cases in Europe

Summary

The objective of this report is to provide an updated analysis of the post-mortem toxicology practices of drug-related deaths (DRD) in Europe and to discuss the effect of these practices on the monitoring of DRDs. (EMCDDA,Lissabon,April 2019)

http://www.emcdda.europa.eu/system/files/publications/10544/Analysis%20of%20practices%20of%20PM%20toxicology%20of%20DRD%20in%20Europe_EMCDDA%20Technical%20report.pdf

Notes from the Field: Unintentional Drug Overdose Deaths with Kratom Detected — 27 States, July 2016–December 2017. 

Olsen EO, O’Donnell J, Mattson CL, Schier JG, Wilson N. 

MMWR Morb Mortal Wkly Rep 2019;68:326–327. doi.org/10.15585/mmwr.mm6814a2.

https://www.cdc.gov/mmwr/volumes/68/wr/mm6814a2.htm

Smokeless tobacco mortality risks: an analysis of two contemporary nationally representative longitudinal mortality studies

Michael T. Fisher, Susan Marie Tan-Torres, Charles L. Gaworski, Ryan A. Black and Mohamadi A. Sarkar

Harm Reduction Journal 2019, 16:27, doi.org/10.1186/s12954-019-0294-6

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-019-0294-6

Kanada / British Columbia. New drug mix causing harder-to-revive overdoses, sparking panic in Vancouver - Etizolam is described as having 10 times the potency of Valium

'The morgues are full and they've had to rent cooling trucks to store bodies' (CBC, Kanada, 12.04.2019)

https://www.cbc.ca/news/canada/british-columbia/new-kind-of-overdose-dtes-benzo-filler-anxiety-depression-drug-making-narcan-fail-1.5096395

Kanada. National report: Apparent opioid-related deaths in Canada (January 2016 to September 2018). Web Based Report. 

Special Advisory Committee on the Epidemic of Opioid Overdoses. 

Ottawa: Public Health Agency of Canada; April 2019. 

https://infobase.phac-aspc.gc.ca/datalab/national-surveillance-opioid-harms-mortality.html

Kanada. In Vancouver, front-line workers are facing ‘a different kind of overdose’ in new synthetic drug

A drug chemically similar to medication for anxiety and sleep disorders that is being cut into heroin and fentanyl is suspected of contributing to a spate of overdoses that leave some users unconscious for hours at a time. (The Globe and Mail, Kanada, 11.04.2019)

https://www.theglobeandmail.com/canada/article-in-vancouver-front-line-workers-face-a-different-kind-of-overdose/

Non drug-related and opioid-specific causes of 3262 deaths in Scotland's methadone-prescription clients, 2009-2015.

Gao L, Robertson JR, Bird SM.

Drug Alcohol Depend. 2019 Apr 1;197:262-270. doi: 10.1016/j.drugalcdep.2019.01.019. 

https://www.sciencedirect.com/science/article/pii/S0376871618305647?via%3Dihub

A retrospective cohort study of mortality rates in patients with an opioid use disorder treated with implant naltrexone, oral methadone or sublingual buprenorphine.

Kelty E, Joyce D, Hulse G.

Am J Drug Alcohol Abuse. 2019 Mar 8:1-7. doi: 10.1080/00952990.2018.1545131.

https://www.tandfonline.com/doi/full/10.1080/00952990.2018.1545131

Kanada. 43 overdoses in a single night in Vancouver: firefighters

A local official posted a startling statistic on Monday about the overdose crisis in Vancouver.

There were 43 overdoses in a single night in the city, Deputy Fire Chief Tyler Moore said. The overdose calls all came in overnight Friday, he said. (CTV News, Kanada, 26.03.2019)

https://bc.ctvnews.ca/43-overdoses-in-a-single-night-in-vancouver-firefighters-1.4352500

USA. Drug overdose deaths involving fentanyl, 2011–2016. 

Spencer MR, Warner M, Bastian BA, Trinidad JP, Hedegaard H. 

National Vital Statistics Reports; vol 68 no 3. Hyattsville, MD: National Center for Health Statistics. 2019.

https://www.cdc.gov/nchs/data/nvsr/nvsr68/nvsr68_03-508.pdf

USA. FDA Grants Purdue Pharma’s Nalmefene HCl Injection Fast Track Designation for the 
Emergency Treatment of Known or Suspected Opioid Overdose

Committed to advancing solutions to the opioid public health crisis, Purdue will not profit from nalmefene HCl. (Purdue Pharma L.P, USA, 13.03.2019)

https://www.purduepharma.com/news-media/2019/03/fda-grants-purdue-pharmas-nalmefene-hcl-injection-fast-track-designation-for-theemergency-treatment-of-known-or-suspected-opioid-overdose/

Cerebellar Hippocampal and Basal Nuclei Transient Edema with Restricted diffusion (CHANTER) Syndrome.

Jasne AS, Alsherbini KH, Smith MS, Pandhi A, Vagal A, Kanter D.

Neurocrit Care. 2019 Feb 20. doi: 10.1007/s12028-018-00666-4.

https://link.springer.com/article/10.1007%2Fs12028-018-00666-4

Potentially deadly and memory-killing effect of opioid abuse explored

Doctors treating drug-overdose patients should be on the lookout for abnormal brain swelling, a byproduct of a mysterious syndrome that can be fatal and may cause profound amnesia in survivors, a new study suggests. (Yale News, USA, 18.03.2019)

https://news.yale.edu/2019/03/18/potentially-deadly-and-memory-killing-effect-opioid-abuse-explored

USA. Opioid crisis: US schools prepare for student overdoses

The US state of Alabama is pioneering a project to train school staff - including teachers, coaches and administrators - how to treat pupils suffering from drug overdoses. (BBC, 11.03.2019)

https://www.bbc.com/news/world-us-canada-47447603

Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2011-2016.

Hedegaard H, Bastian BA, Trinidad JP, Spencer M, Warner M.

Natl Vital Stat Rep. 2018 Dec;67(9):1-14.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/30707673

Indien. Mehr als 150 Tote nach Konsum von gepanschtem Schnaps in Indien

Im Bundesstaat Assam sind mehr als 150 Menschen nach dem Konsum von illegal gebranntem Schnaps gestorben. (aerzteblatt.de, 25.02.2019)

https://www.aerzteblatt.de/nachrichten/101298/Mehr-als-150-Tote-nach-Konsum-von-gepanschtem-Schnaps-in-Indien

Kanada. B.C. moves to stem high rate of overdose deaths by recent inmates

A coroner’s death review panel last year found about two-thirds B.C. residents who died of an illegal drug overdose over a 19-month period had recent contact with the criminal justice system. (Vancouver Sun, Kanada, 30.01.2019)

https://vancouversun.com/news/local-news/b-c-moves-to-stem-high-rate-of-overdose-deaths-by-recent-inmates

INTERVIEW: „Die fallenden Mortalitätsraten stehen im Gegensatz zu den Ergebnissen in den USA“

Interview mit Julia Schmieder, Doktorandin in der Abteilung Staat am DIW Berlin. (DIW Wochenbericht, Hrsg.: DIW - Deutsches Institut für Wirtschaftsforschung e. V., Berlin, 86. Jahrgang, 7 und 8/2019, 13.02.2019)

https://www.diw.de/documents/publikationen/73/diw_01.c.613176.de/19-7-2.pdf

Todesfälle durch Suizid, Alkohol und Drogen sinken deutlich bei Männern und Frauen in Ost- und Westdeutschland

Von Peter Haan, Anna Hammerschmid, Robert Lindner und Julia Schmieder

Zwischen 1991 und 2015 ist die Zahl der sogenannten „Deaths of Despair“ bei Menschen mittleren Alters in Deutschland deutlich gesunken. Dies gilt auch bei Unterscheidung nach Geschlecht und nach Ost- und Westdeutschland für alle Gruppen. Dies steht in deutlichem Kontrast zu den USA, wo sich zwischen 1991 und 2014 die Zahl entsprechender Todesfälle für nichthispanische Weiße mehr als verdoppelt hat. Möglicher Grund ist die bessere Absicherung ökonomischer und gesundheitlicher Risiken in Deutschland. Gleichzeitig bleibt die Zahl der Todesfälle durch Suizid, Alkohol und Drogen bei Männern in Ostdeutschland deutlich höher als in Westdeutschland. (DIW Wochenbericht, Hrsg.: DIW - Deutsches Institut für Wirtschaftsforschung e. V., Berlin, 86. Jahrgang, 7 und 8/2019, 13.02.2019) 

https://www.diw.de/documents/publikationen/73/diw_01.c.613172.de/19-7.pdf

Premature mortality from all causes and drug poisonings in the USA according to socioeconomic status and rurality: an analysis of death certificate data by county from 2000–15

Shiels, Meredith S et al.

The Lancet Public Health , Volume 4 , Issue 2 , e97 - e106 

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30208-1/fulltext

UK. 'Xanax' linked to more than 200 deaths

At least 204 deaths have been linked to the misuse of anxiety drug Xanax in the UK since 2015, figures seen by the BBC's Victoria Derbyshire programme reveal.

Of these, there were 126 fatalities in Scotland between 2015 and 2017.

Counterfeit Xanax bars with a street value of more than £1m have been seized at UK ports and airports since 2016. (BBC, 05.02.2019)

https://www.bbc.com/news/health-47055499

Loperamid. Study finds rise in overdoses from opioids in diarrhea drug

A Rutgers study has uncovered a new threat in the opiate epidemic: Overdoses of loperamide, an over-the-counter diarrhea medication, have been steadily increasing in number and severity nationwide over five years. (MedicalXpress, USA, 04.02.2019)

https://medicalxpress.com/news/2019-02-overdoses-opioids-diarrhea-drug.html

England/Wales. Drug-related deaths in England - local authorities and how they are responding

Drug-related deaths in England3NATDrug-related deaths (DRDs) are at their highest level since records began in 1993 with 3,756 DRDs in England and Wales last year, 53% of which related to opiate use. Almost a third of all deaths from overdose in 2016 in Europe happened in the UK. This constitutes a public health and humanitarian crisis which must be addressed urgently. (NAT - National AIDS Trust, Januar 2019)

https://www.nat.org.uk/sites/default/files/publications/drug_related_deaths_in_england.pdf