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Association of Cannabis With Cognitive Functioning in Adolescents and Young AdultsA Systematic Review and Meta-analysis.

Scott JC, Slomiak ST, Jones JD, Rosen AFG, Moore TM, Gur RC.

JAMA Psychiatry. Published online April 18, 2018. doi:10.1001/jamapsychiatry.2018.0335


Associations between cannabis use and cognitive functioning in cross-sectional studies of adolescents and young adults are small and may be of questionable clinical importance for most individuals. Furthermore, abstinence of longer than 72 hours diminishes cognitive deficits associated with cannabis use. Although other outcomes (eg, psychosis) were not examined in the included studies, results indicate that previous studies of cannabis in youth may have overstated the magnitude and persistence of cognitive deficits associated with use. Reported deficits may reflect residual effects from acute use or withdrawal. Future studies should examine individual differences in susceptibility to cannabis-associated cognitive dysfunction.


The Spice of Death: The Science behind Tainted “Synthetic Marijuana” - Experts describe how rat poison linked to a recent bleeding outbreak does its damage

Three people died and more than 100 have been sickened in the past few weeks after taking synthetic cannabinoids, human-made compounds that target the same brain receptors as marijuana. Symptoms documented by poison centers—first mostly in the Midwest, and now in Maryland—include unexplained bruising, coughing up blood, bleeding from the nose and gums, blood in urine and feces, and excessively heavy menstruation.

An ongoing investigation has identified a likely culprit in the blood of those affected: rat poison, specifically brodifacoum. (Scientific American, 17.04.2018)


Cocaine-induced Type-A Aortic Dissection Extending to the Common Iliac Arteries.

Mohamed MA, Abraham R, Maraqa TI, Elian S.

Cureus. 2018 Jan 12;10(1):e2059. doi: 10.7759/cureus.2059.


Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015.

GBD 2015 Tobacco Collaborators.

Lancet. 2017 May 13;389(10082):1885-1906. doi: 10.1016/S0140-6736(17)30819-X.


Cracking the Crack Dance: A Case Report on Cocaine-induced Choreoathetosis.

Narula N, Siddiqui F, Katyal N, Krishnan N, Chalhoub M.

Cureus. 2017 Dec 22;9(12):e1981. doi: 10.7759/cureus.1981.


The associations between psychotic experiences and substance use and substance use disorders: findings from the World Health Organization World Mental Health surveys.

Degenhardt, L., Saha, S., Lim, C. C. W., AguilarGaxiola, S., AlHamzawi, A., Alonso, J., Andrade, L. H., Bromet, E. J., Bruffaerts, R., CaldasdeAlmeida, J. M., de Girolamo, G., Florescu, S., Gureje, O., Haro, J. M., Karam, E. G., Karam, G., KovessMasfety, V., Lee, S., Lepine, J.P., Makanjuola, V., MedinaMora, M. E., Mneimneh, Z., NavarroMateu, F., Piazza, M., PosadaVilla, J., Sampson, N. A., Scott, K. M., Stagnaro, J. C., Ten Have, M., Kendler, K. S., Kessler, R. C., McGrath, J. J., and on behalf of the WHO World Mental Health Survey Collaborators (2018)

Addiction, 113: 924–934. doi: 10.1111/add.1414.


Altered Gray Matter Volume and Disrupted Functional Connectivity of Dorsolateral Prefrontal Cortex in Males with Heroin Dependence.

Lin HC, Wang PW, Wu HC, Ko CH, Yang YH, Yen CF.

Psychiatry Clin Neurosci. 2018 Mar 27. doi: 10.1111/pcn.12655.



Neurotoxicity Induced by Mephedrone: An up-to-date Review.

Pantano F, Tittarelli R, Mannocchi G, Pacifici R, di Luca A, Busardò FP, Marinelli E.

Curr Neuropharmacol. 2017;15(5):738-749. doi: 10.2174/1570159X14666161130130718. Review.


USA. Illinois and Maryland Departments of Public Health Issue Alerts on Synthetic Cannabinoid Products

The Maryland Department of Health and Maryland Poison Center issued a memorandum yesterday to Emergency departments, emergency medical services, health care facilities, and local health departments reporting on a case in central Maryland in which a user of synthetic cannabinoids was hospitalized with symptoms similar to those experienced by cases in Illinois linked to synthetic cannabinoid product containing a rat poison that acts as an anticoagulant. (NIH-NIDA, USA, April 2018)


Reversible Thrombocytopenia after Gabapentin in an HIV-Positive Patient.

Basith M, Francis A, Bellon A.

Case Rep Psychiatry. 2018 Jan 4;2018:5927065. doi: 10.1155/2018/5927065.


USA. Synthetic Cannabis Laced With Poison Linked to Severe Bleeding, CDC Warns

(...) From March 10 through April 5, 94 people have presented to emergency departments (89 in Illinois, two in Indiana, one in Maryland, one in Missouri, and one in Wisconsin) with potentially life-threatening vitamin K–dependent antagonist coagulopathy after using synthetic cannabinoids. Two individuals have died.

Laboratory testing confirmed that at least 18 individuals had been exposed to brodifacoum, a highly lethal vitamin K antagonist anticoagulant. It is used in commercial products for killing rodents and other pests. (Medscape, USA, 06.04.2018)


International Consensus Statement on Screening, Diagnosis and Treatment of Substance Use Disorder Patients with Comorbid Attention Deficit/Hyperactivity Disorder.

Crunelle CL, van den Brink W, Moggi F, Konstenius M, Franck J, Levin FR, van de Glind G, Demetrovics Z, Coetzee C, Luderer M, Schellekens A; ICASA consensus group, Matthys F.

Eur Addict Res. 2018;24(1):43-51. doi: 10.1159/000487767.


Physical pain is common and associated with nonmedical prescription opioid use among people who inject drugs.

Dahlman D, Kral AH, Wenger L, Hakansson A, Novak SP.

Subst Abuse Treat Prev Policy. 2017 May 30;12(1):29. doi: 10.1186/s13011-017-0112-7.


Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study.

Fleet JL, Dixon SN, Kuwornu PJ, Dev VK, Montero-Odasso M, Burneo J, et al. (2018)

PLoS ONE 13(3): e0193134. doi.org/10.1371/journal.pone.0193134


Lead poisoning outbreak among opium users in the Islamic Republic of Iran, 2016-2017.

Ghane T, Zamani N, Hassanian-Moghaddam H, Beyrami A, Noroozi A.

Bull World Health Organ. 2018 Mar 1;96(3):165-172. doi: 10.2471/BLT.17.196287.


Cannabinoid Hyperemesis Syndrome: Public Health Implications and a Novel Model Treatment Guideline.

Lapoint J, Meyer S, Yu CK, Koenig KL, Lev R, Thihalolipavan S, Staats K, Kahn CA.

West J Emerg Med. 2018 Mar;19(2):380-386. doi: 10.5811/westjem.2017.11.36368.


Kompartmentsyndrom des Unterarms nach intraarterieller Autoinjektion - Mit einem Gemisch aus Methadon, Flunitrazepam, Speichel und Wasser

Kamphuis, S.J.M., Jandali, A.R., Jung, F.J. et al. Unfallchirurg (2018). doi.org/10.1007/s00113-018-0482-y



Psychoactive substances and violent offences: A retrospective analysis of presentations to an urban emergency department in Switzerland.

Liakoni E, Gartwyl F, Ricklin M, Exadaktylos AK, Krähenbühl S (2018)

PLoS ONE 13(3): e0195234. doi.org/10.1371/journal.pone.0195234


Occupational Hazards Associated With Harvesting and Processing Cannabis

Kerton R. Victory, PhD; James Couch, PhD; Brian Lowe, PhD; Brett J. Green, PhD

Morbidity and Mortality Weekly Report. 2018;67(8):259-260. 


Evaluation of the effect of methamphetamine on traumatic injury complications and outcomes.

Neeki MM, Dong F, Liang L, Toy J, Carrico B, Jabourian N, Sin A, Hussain F, Brown S, Safdari K, Borger R, Wong D.

Addict Sci Clin Pract. 2018 Mar 29;13(1):11. doi: 10.1186/s13722-018-0112-6.


Opium Consumption and the Incidence of Cancer: Does Opium Account as an Emerging Risk Factor for Gastrointestinal Cancer?

Alzaidi MA, Arab HA, Amanpour S, Shirkoohi R, Muhammadnejad S, Sasani F.

J Gastrointest Cancer. 2018 Jan 24. doi: 10.1007/s12029-017-0050-7.



A Case of Levamisole-Induced Agranulocytosis.

Kassim T, Chintalacheruvu L, Bhatty O, Selim M, Diab O, Nayfeh A, Manikkam Umakanthan J, Gbadamosi-Akindele M.

Case Rep Hematol. 2018 Feb 11;2018:7341835. doi: 10.1155/2018/7341835.