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The Effect of Transcranial Direct Current Stimulation on Relapse, Anxiety, and Depression in Patients With Opioid Dependence Under Methadone Maintenance Treatment: A Pilot Study.

Sadeghi Bimorgh M, Omidi A, Ghoreishi FS, Rezaei Ardani A, Ghaderi A, Banafshe HR.

Front Pharmacol. 2020 Apr 3;11:401. doi: 10.3389/fphar.2020.00401. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145941/

High prevalence of albuminuria amongst people who inject drugs: A cross-sectional study.

McGowan CR, Wright T, Nitsch D, Lewer D, Brathwaite R, Scott J, Hope V, Ciccarone D, Dunn J, Gillmore J, Story A, Harris M.

Sci Rep. 2020 Apr 27;10(1):7059. doi: 10.1038/s41598-020-63748-4.

https://www.nature.com/articles/s41598-020-63748-4

Rapid development of pulmonary hypertension and right ventricular failure due to large vessel intravascular microcrystalline cellulosis in an intravenous drug user.

Amass T, Cumplido J, Aswad B, Whittenhall M, Ventetuolo C, Klinger J.

Pulm Circ. 2020 Apr 6;10(1):2045894020907871. doi: 10.1177/2045894020907871. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137130/

Substance Induced Mood Disorders.

Revadigar N, Gupta V.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.
2020 Mar 9.

PMID: 32310347

https://www.ncbi.nlm.nih.gov/books/NBK555887/

Opium use and subsequent incidence of cancer: results from the Golestan Cohort Study

Sheikh, Mahdi et al.

The Lancet Global Health, Volume 8, Issue 5, e649 - e660 

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(20)30059-0/fulltext

Sleeping Patterns in Patients with Opioid Use Disorder: Effects of Opioid Maintenance Treatment and Detoxification.

Chrobok AI, Krause D, Winter C, Plörer D, Martin G, Koller G, Adorjan K, Canolli M, Adam R, Wagner EM, Peles E, Paul D, Vogel T, Pogarell O.

J Psychoactive Drugs. 2020 Apr 17:1-8. doi: 10.1080/02791072.2020.1751900.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/32299305

Dispensation of attention deficit hyperactivity disorder (ADHD) medications in patients receiving opioid agonist therapy; a national prospective cohort study in Norway from 2015 to 2017.

Vold JH, Aas C, Skurtveit S, Odsbu I, Chalabianloo F, Halmøy A, Johansson KA, Fadnes LT.

BMC Psychiatry. 2020 Mar 12;20(1):119. doi: 10.1186/s12888-020-02526-y.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068965/

Prolonged Sleep Apnea in Two Patients with a History of Opium Abuse -A Case Report.

Asadpour H, Naghibi SM, Rahimi S, Sharafkhaneh A, Afshari Saleh L, Rezaee Talab F, Amini M, Nikzad F.

Iran J Otorhinolaryngol. 2020 Mar;32(109):127-131. doi: 10.22038/ijorl.2020.41832.2365.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085923/

Infected femoral pseudoaneurysms in intravenous drug abusers: a decade of experience from a Singapore tertiary centre.

Samarakoon LB, Ho DCY, Tan YK, Kum SWC, Lim DM.

Singapore Med J. 2020 Mar 9. doi: 10.11622/smedj.2020011. 

http://www.smj.org.sg/sites/default/files/OA-2018-130-epub.pdf

Acute Susac Syndrome in a Recent User of Adulterated Cocaine: Levamisole as a Triggering Factor?

De Baerdemaeker K, Mabiglia C, Hantson P, Di Fazio V, Duprez T, Kozyreff A, van Pesch V, Sellimi A.

Case Rep Neurol. 2020 Feb 21;12(1):78-83. doi: 10.1159/000506043. e

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098328/

Comparing Medical Comorbidities Between Opioid and Cocaine Users: A Data Mining Approach.

Kim YM.

Addict Health. 2019 Oct;11(4):223-233. doi: 10.22122/ahj.v11i4.242.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073808/

PTSD and opioid use: implications for intervention and policy.

Dahlby L, Kerr T.

Subst Abuse Treat Prev Policy. 2020 Mar 16;15(1):22. doi: 10.1186/s13011-020-00264-8.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077145/

Marijuana Allergies on the Rise

"Cannabis sativa is a weed and it causes reactions just like any other pollen allergy," said William Silvers, MD, from the University of Colorado School of Medicine in Aurora.

Silvers' clinic began to see people with allergic reactions to the plant after the increase in direct exposure that accompanied the legalization of recreational marijuana in Colorado. For people with allergic tendencies, first- and second-hand exposure to C. sativa will increase "classic responses," such as allergic rhinitis, sneezing, wheezing, itching, and asthma, he told Medscape Medical News. (Medscape, 06.03.2020)

https://www.medscape.com/viewarticle/926358

Long-term Opioid Use in Men Linked to Hypogonadism

NATIONAL HARBOR, Maryland ― Long-term opioid use in men is linked to a significantly increased risk for hypogonadism, new research suggests.

Findings from a retrospective case-control study show that men who used long-acting opioids on a long-term basis had close to a 1.5-fold increased risk of developing the condition. Moreover, for every increase in 100 maximum morphine equivalent daily dose (MEDD), there was a 44% increase in risk. (Medscape Medical News, USA, 09.03.2020)

https://www.medscape.com/viewarticle/926423

Connections between Sleep and Substance Use Disorders.

NIDA. (2020, March 9). 

https://www.drugabuse.gov/about-nida/noras-blog/2020/03/connections-between-sleep-substance-use-disorders

Fallberichte von drei Patienten mit akuter Lungenschädigung nach Gebrauch von E-Zigaretten

Three patients with acute pulmonary damage following the use of e-cigarettes—a case series

Dtsch Arztebl Int 2020; 117: 177-82; DOI: 10.3238/arztebl.2020.0177

Suhling, Hendrik; Welte, Tobias; Fuehner, Thomas

https://www.aerzteblatt.de/archiv/212897

Clinical profile and outcomes of opioid abuse gastroenteropathy: an underdiagnosed disease entity.

Mahajan R, Gupta Y, Singh A, Dhiman P, Midha V, Kakkar C, Narang V, Mehta V, Saggar K, Sood A.

Intest Res. 2020 Feb 25. doi: 10.5217/ir.2019.00104. 

https://irjournal.org/journal/view.php?doi=10.5217/ir.2019.00104

Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis.

Yazdanian M, Armoon B, Noroozi A, Mohammadi R, Bayat AH, Ahounbar E, Higgs P, Nasab HS, Bayani A, Hemmat M.

BMC Oral Health. 2020 Feb 10;20(1):44. doi: 10.1186/s12903-020-1010-3.

https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-020-1010-3

Increased risk of HIV and other drug-related harms associated with injecting in public places: national bio-behavioural survey of people who inject drugs.

Trayner KMA, McAuley A, Palmateer NE, Goldberg DJ, Shepherd SJ, Gunson RN, Tweed EJ, Priyadarshi S, Milosevic C, Hutchinson SJ.

Int J Drug Policy. 2020 Jan 22;77:102663. doi: 10.1016/j.drugpo.2020.102663.

https://www.sciencedirect.com/science/article/pii/S0955395920300049

Substance Use + Mental Health in Teens and Young Adults 

Your Guide to Recognizing and Addressing Co-occurring Disorders 

Center on Addiction and  Partnership for Drug-Free Kids, USA, 2020 

https://drugfree.org/wp-content/uploads/2019/02/Substance-Use-Mental-Health-in-Teens-and-Young-Adults.pdf

EMCDDA. Drug-related hospital emergency presentations in Europe: update from the Euro-DEN Plus expert network

Summary

This report presents the latest findings on drug-related hospital emergencies from a network of sentinel hospitals across Europe. Almost 24 000 emergency presentations were recorded at 32 sentinel hospitals over the first 4 years of the project. The data reveal that the substances most commonly involved in acute drug toxicity presentations include heroin, cocaine and cannabis. Prescription medicines are frequently reported. The report also sheds light on other aspects of drug-related emergencies such as clinical features, geographical variation, outcomes, demographics and time patterns. (EMCDDA, Lissabon, EMCDDA, Februar 2020 

http://www.emcdda.europa.eu/publications/technical-reports/drug-related-hospital-emergency-presentations-in-europe_en

Infective endocarditis: trends, surgical outcomes, and controversies.

Jamil M, Sultan I, Gleason TG, Navid F, Fallert MA, Suffoletto MS, Kilic A.

J Thorac Dis. 2019 Nov;11(11):4875-4885. doi: 10.21037/jtd.2019.10.45. Review.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940216/

Cocaine/amphetamine-induced accelerated atherosclerosis, coronary spasm and thrombosis, and refractory ventricular fibrillation.

den Uil CA, Ligthart JMR, Mandigers L, den Dekker WK.

Eur Heart J Case Rep. 2019 Dec;3(4):1-2. doi: 10.1093/ehjcr/ytz167. Epub 2019 Sep 24.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939810/

Brugada syndrome, Brugada phenocopy, or simply arrythmia induced by cocaine intoxication?

Cepas-Guillén PL, Pujol-López M, San Antonio R, Arbelo E, Salgado E, Brugada J.

Emergencias. 2020 Feb;32(1):72-74. Spanish, English. 

http://emergencias.portalsemes.org/descargar/sndrome-de-brugada-fenocopia-de-brugada-o-solo-intoxicacin-arritmognica/english/

Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management.

Pergolizzi JV Jr, Raffa RB, Rosenblatt MH.

J Clin Pharm Ther. 2020 Jan 27. doi: 10.1111/jcpt.13114. 

https://onlinelibrary.wiley.com/doi/full/10.1111/jcpt.13114

Cardiovascular Complications of Chronic Opium Consumption: A Narrative Review Article.

Ziaee M, Hajizadeh R, Khorrami A, Sepehrvand N, Momtaz S, Ghaffari S.

Iran J Public Health. 2019 Dec;48(12):2154-2164. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974854/

Exploring psychological symptoms and associated factors in patients receiving medication-assisted treatment for opioid-use disorder.

Rosic T, Worster A, Thabane L, Marsh DC, Samaan Z.

BJPsych Open. 2020 Jan 8;6(1):e8. doi: 10.1192/bjo.2019.99.

https://www.cambridge.org/core/journals/bjpsych-open/article/exploring-psychological-symptoms-and-associated-factors-in-patients-receiving-medicationassisted-treatment-for-opioiduse-disorder/32B35973DABF60D7F15C2A7708A17632

The Role of Peripheral Opioid Receptors in Triggering Heroin-induced Brain Hypoxia.

Perekopskiy D, Afzal A, Jackson SN, Muller L, Woods AS, Kiyatkin EA.

Sci Rep. 2020 Jan 21;10(1):833. doi: 10.1038/s41598-020-57768-3.

https://www.nature.com/articles/s41598-020-57768-3

Beyond Antibiotics: A Practical Guide for the Infectious Disease Physician to Treat Opioid Use Disorder in the Setting of Associated Infectious Diseases.

Seval N, Eaton E, Springer SA.

Open Forum Infect Dis. 2019 Dec 24;7(1):ofz539. doi: 10.1093/ofid/ofz539. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979000/

Methadone-induced encephalopathy: a case series and literature review.

Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L.

BMC Med Imaging. 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969410/

  1. Fournier's Gangrene and Intravenous Drug Abuse: an Unusual Case Report and Review of The Literature.
  2. COPD and asthma in patients with opioid dependency: a cross-sectional study in primary care.
  3. Buprenorphine and Methadone as Opioid Maintenance Treatments for Heroin-Addicted Patients Induce Oxidative Stress in Blood.
  4. Hydromorphone and the risk of infective endocarditis among people who inject drugs: a population-based, retrospective cohort study.
  5. USA. Most EVALI Patients Used THC-Containing Products as New Cases Continue To Decli