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Association of Opioid and Stimulant Use Disorder Diagnoses With Fatal and Nonfatal Overdose Among People With a History of Incarceration. 

Palis H, Gan W, Xavier C, et al. 

JAMA Netw Open. 2022;5(11):e2243653. doi:10.1001/jamanetworkopen.2022.43653


EMCDDA. Recreational use of nitrousoxide: a growing concern for Europe

European Monitoring Centre for Drugs and Drug Addiction (2022), 

Publications Office of the European Union, Luxembourg.


Sensitive periods in development and risk for psychiatric disorders and related endpoints: a systematic review of child maltreatment findings

Schaefer, Jonathan D et al.

The Lancet Psychiatry, Volume 9, Issue 12, 978 - 991 


Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios. 

Englund, A., Oliver, D., Chesney, E. et al.

Neuropsychopharmacol. (2022). doi.org/10.1038/s41386-022-01478-z


Major-Depression: Psilocybin erzielt in Phase-2-Studie begrenzte Wirkung

London – Die einmalige Gabe des Halluzinogens Psilocybin im Rahmen einer eintägigen Therapiesitzung kann die Symptome von Patienten mit Major-Depressionen über mehrere Wochen lindern. Eine signifikante Wirkung wurde in einer Phase-2-Studie jedoch nur in der höchsten Dosis erzielt.

Nach den im New England Journal of Medicine (2022; DOI: 10.1056/NEJMoa2206443) publizierten Ergebnissen erreichte jeder 3. Patient eine Remission, deren Dauer allerdings nicht absehbar ist. (aerzteblatt.de, 07.11.2022)


An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats. 

Haile CN, Baker MD, Sanchez SA, Lopez Arteaga CA, Duddupudi AL, Cuny GD, Norton EB, Kosten TR, Kosten TA. 

Pharmaceutics. 2022; 14(11):2290. doi.org/10.3390/pharmaceutics14112290


Development of Hepatocellular Carcinoma in Patients Aged 75-84 Years With Chronic Hepatitis C Treated With Direct-Acting Antivirals.

Ogawa E, Nomura H, Nakamuta M, Furusyo N, Kajiwara E, Dohmen K, Kawano A, Ooho A, Azuma K, Takahashi K, Satoh T, Koyanagi T, Ichiki Y, Kuniyoshi M, Yanagita K, Amagase H, Morita C, Sugimoto R, Kato M, Shimoda S, Hayashi J; Kyushu University Liver Disease Study (KULDS) Group. 

J Infect Dis. 2022 Aug 26;226(3):431-440. doi: 10.1093/infdis/jiaa359. PMID: 32584386; PMCID: PMC9417129.


Effects of media representations of drug related deaths on public stigma and support for harm reduction. 

Sumnall HR, Atkinson AM, Montgomery C, Maynard OM, Nicholls J. 

Int J Drug Policy. 2022 Nov 15;111:103909. doi: 10.1016/j.drugpo.2022.103909. Epub ahead of print. PMID: 36399962.


'As for dignity and respect…. me bollix': A human rights-based exploration of service user narratives in Irish methadone maintenance treatment. 

Healy R, Goodwin J, Kelly P. 

Int J Drug Policy. 2022 Nov 6;110:103901. doi: 10.1016/j.drugpo.2022.103901. Epub ahead of print. PMID: 36351318.


A potential paradigm shift in opioid crisis management: The role of pharmacogenomics. 

Eapen-John D, Mohiuddin AG, Kennedy JL. 

World J Biol Psychiatry. 2022 Jul;23(6):411-423. doi: 10.1080/15622975.2021.2012397. Epub 2022 Jan 14. PMID: 34854362.


Ribosomal DNA transcription is increased in the left nucleus accumbens of heroin-dependent males. 

Gos T, Steiner J, Trübner K, Krzyżanowska M, Kaliszan M. 

Eur Arch Psychiatry Clin Neurosci. 2022 Dec;272(8):1603-1609. doi: 10.1007/s00406-022-01423-7. Epub 2022 May 14. PMID: 35567616; PMCID: PMC9106793.


USA. Researchers find 2.8% of pregnancies were exposed to opioids

Opioid use during pregnancy may lead to adverse long-term infant and child outcomes. Targeted public health strategies have been employed to reduce opioid use in reproductive-aged persons, but there has been a lack of research that adequately describes the individuals in the United States who actually use opioids during pregnancy. The first nationwide, geographically diverse study of pregnant people to describe the epidemiology of opioid use, including the demographic and medical characteristics of these people, helps to fill this gap. (University of Minnesota, USA, 21.11.2022)


Comparing Projected Fatal Overdose Outcomes and Costs of Strategies to Expand Community-Based Distribution of Naloxone in Rhode Island. 

USA. Zang X, Bessey SE, Krieger MS, et al. 

JAMA Netw Open. 2022;5(11):e2241174. doi:10.1001/jamanetworkopen.2022.41174


Providing naloxone to people who are prescribed opioids is a cost-effective way of preventing opioid overdose deaths

Much of the research on the effects of naloxone distribution has focused on people with opioid use disorder. This study investigated the public health impact and cost-effectiveness of naloxone access for individuals prescribed opioid medications, more generally, to help inform a comprehensive naloxone distribution strategy. (Recovery Research Institute, USA, November 2022)


USA. Harm-reduction efforts needed to curb overdose epidemic (AMA)

The U.S. drug-overdose epidemic continues to worsen as the number of deaths grew by nearly 15% in 2021—a grim total fueled by a 23% rise in the number of deaths linked to illicitly manufactured fentanyl—highlighting a need to encourage harm-reduction measures, according to a resolution presented at the 2022 AMA Interim Meeting. (AMA – American Medical Association, USA, 15.11.2022)


Forschungsbericht / Research Report. Kampagne zur Veränderung der Drogen-Applikationsform von intravenös zu inhalativ - Eine Mitarbeiter_innenbefragung in deutschen Suchthilfeeinrichtungen [Campaign to Change the Mode of Application of Drugs from Intravenous to Inhalative – A Survey of Staff Members of German Drug Services]

HEINO STÖVER (Prof. Dr.), DIRK SCHÄFFER (Referatsleiter DAH) & STEFAN FÖRSTER (Dipl. Soz.)

Akzeptanzorientierte Drogenarbeit/Acceptance-Oriented Drug Wor, ISSN 1861-0110 INDRO e.V., 2019


The Global State of Tobacco Harm Reduction 2022: The Right Side of History

This Briefing Paper, drawn from The Global State of Tobacco Harm Reduction 2022: The Right Side of History, considers when, how and why the approach now known as tobacco harm reduction really began. When was it established that smoking-related diseases were not caused by nicotine, but by the thousands of chemicals released when tobacco burns? Who began looking for safer ways to use nicotine – and why were there so many false starts? How did nicotine consumers themselves influence the development both of safer products, and of tobacco harm reduction itself? What has been the response of public health and tobacco control organisations to these changes in nicotine use? (The Global State of Tobacco Harm Reduction (GSTHR), 2022 (finanziert von Philipp Morris, Anm.)


Webinar. „Ärztliche Leichenschau, drogenassoziierte Todesfälle und Möglichkeiten des Drogennachweises“ – 30.11.2022, 17.00 – 19.30 Uhr

Wir freuen uns sehr darüber, dass Herr Dr. Sven Hartwig, Oberarzt und Abteilungsleiter der forensischen Toxikologie / Institut für Rechtsmedizin Charité Berlin an diesem Tag für Sie referieren wird. 

Im Rahmen seiner aktuellen Tätigkeit verfügt Herr Dr. Hartwig über eine breite Expertise in diesem Teilgebiet der Medizin. Gerne können Sie sich aktiv während und nach dem Vortrag einbringen.

Bitte melden Sie sich über die E-mail Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein! an. (Hexal AG)


A death by any other name: substance-induced or substance-related mortality

Hjorthøj, Carsten et al.

The Lancet Psychiatry, Volume 0, Issue 0 


Time to Stop Using the Word “Smoker”: Reflecting on the Role of Language in Advancing the Field of Nicotine and Tobacco Research,

Renee D Goodwin, PhD, MPH, Lisa K Walker, PhD, 

Nicotine & Tobacco Research, 2022;, ntac218,  doi.org/10.1093/ntr/ntac218


Beyond co-production: The construction of drug checking knowledge in a Canadian supervised injection facility. 

Betsos A, Valleriani J, Boyd J, McNeil R. 

Soc Sci Med. 2022 Jul 21;314:115229. doi: 10.1016/j.socscimed.2022.115229. Epub ahead of print. PMID: 36274456.



UK. Drug checking services make festivals safer, research shows

New research has found that drug checking services at festivals reduce the possibility of drug-related harm, provide opportunities for targeted health interventions amongst higher risk drug users and, on balance, do not result in increased quantities of drugs being consumed.

Research published in a special issue of the journal Drugs, Habits and Social Policy focused on drug checking, analysed the provision of drug checking services available to hundreds of thousands of festival-goers over three years (2016-2018).

The study was the first of its kind that assessed both the positive and negative impact of providing drug checking across a three-year period. (University of Liverpool, UK, 08.11.2022)


Was Harm Reduction ist und warum wir mehr davon brauchen

Wortwörtlich übersetzt bedeutet harm reduction „Schadensreduzierung.“ Obwohl die Entwicklung erster harm reduction-Maßnahmen schon in den 1920er-Jahren begann, ist das Prinzip erst in den 1980er-Jahren bekannt geworden. In dieser Zeit wurden erstmals Spritzenprogramme als Antwort auf die HIV-Ausbreitung unter Menschen, die Drogen injizieren, eingesetzt. Das oberste Ziel von harm reduction ist es, mögliche Schäden von Drogengebrauch mit sogenannten safer use-Praktiken zu reduzieren oder zu verhindern. (Melissa Scharwey, Ana Liffey Drug Project, Irland, 2020)


Performance Measurement for Opioid Use Disorder Medication Treatment and Care Retention. 

Williams AR, Mauro CM, Feng T, Wilson A, Cruz A, Olfson M, Crystal S, Samples H, Chiodo L. 

Am J Psychiatry. 2022 Oct 26:appiajp20220456. doi: 10.1176/appi.ajp.20220456. Epub ahead of print. PMID: 36285405.


A Systematic Scoping Review of Peridelivery Pain Management for Pregnant People With Opioid Use Disorder: From the Society for Obstetric Anesthesia and Perinatology and Society for Maternal Fetal Medicine. 

Lim G, Soens M, Wanaselja A, Chyan A, Carvalho B, Landau R, George RB, Klem ML, Osmundson SS, Krans EE, Terplan M, Bateman BT. 

Anesth Analg. 2022 Nov 1;135(5):912-925. doi: 10.1213/ANE.0000000000006167. Epub 2022 Sep 22. PMID: 36135926; PMCID: PMC9588509.


Combating illicit fentanyl: Will increased Chinese regulation generate a public health crisis in India? 

Wang C, Lassi N. 

Front Public Health. 2022 Oct 14;10:969395. doi: 10.3389/fpubh.2022.969395. PMID: 36311594; PMCID: PMC9614337.


Pro und Contra: Starken Rauchern sollten vorübergehend E-Zigaretten zum Rauchverzicht empfohlen werden

Berlin – E-Zigaretten sind ein beliebtes Mittel zum Rauchstopp. Bisher durchgeführte rando­misiert kontrollierte Studien zeigen, dass E-Zigaretten die Tabakentwöhnung unterstützen können (2021; DOI: 10.1002/14651858.CD010216.pub5). (aerzteblatt.de, 29.10.2022)



Hrsg.: Bayerische Akademie für Sucht- und Gesundheitsfragen


subLetter. Ausgabe 6/2022

Hrsg.: IWW Institut für Wissen in der Wirtschaft GmbH im Auftrag der Hexal AG.


Addiction, Volume 117, Issue 12, Pages: 2967-3178, December 2022