What constitutes safe and effective dose titration of methadone and buprenorphine/naloxone? protocol for a population-based target trial emulation.  Mondol MH, Zanette M, Min JE, Kurz M, Platt RW, Seaman S, Bach P, Karim ME, Socías ME, Gustafs…

Phase I metabolism of the methadone analog methiodone (IC-26) in pooled human liver microsomes and its detection in seven authentic human cases.  Kutzler J, Postupka A, Auwärter V.  Arch Toxicol. 2026 Sep 16. doi: 10.1007/s00204-026-0454…

Visit-level clinical correlates of next-visit heroin-positive urine in methadone maintenance treatment: A repeated-events analysis from Taiwan.  Yen TT, Lee SW, Jou MJ, Chou TN, Hsu CY, Chen IC, Chang TG.  J Subst Use Addict Treat. 2026…

A study of positive and negative factors associated with tapering off methadone maintenance treatment.  Kumar K, Shekhawat BS, Yadav S, Gothwal R, Rangrez MA.  Indian J Psychiatry. 2026 Jul;68(7):634-638. doi: 10.4103/indianjpsychiatry_6…

Methadone Maintenance Treatment vs. Long-Term Abstinence Without Opioid Agonist: Epigenome-Wide Study of DNA Methylation.  Levran O, Li J, Sason A, Adelson M, Peles E.  Epigenomes. 2026 May 5;10(2):29. doi: 10.3390/epigenomes10020029. PM…

Methadone: The Right Dose, Every Day – Audio/Transskript In this episode of ASAM Practice Pearls, In this episode of ASAM Practice Pearls, Dr. Elizabeth Salisbury-Afshar is joined by Drs. Ruth Potee and Ari Kriegsman to explore highlights from…