A- A A+

Effectiveness of Mindfulness-based Relapse Prevention on Quality of Life and Craving in Methadone-treated Patients: A Randomized Clinical Trial.

Yaghubi M, Zargar F.

Addict Health. 2018 Oct;10(4):250-259. doi: 10.22122/ahj.v10i4.573.


Exploring the Effects of Vitamin D Supplementation on Cognitive Functions and Mental Health Status in Subjects Under Methadone Maintenance Treatment.

Ghaderi A, Rasouli-Azad M, Farhadi MH, Mirhosseini N, Motmaen M, Pishyareh E, Omidi A, Asemi Z.

J Addict Med. 2019 May 24. doi: 10.1097/ADM.0000000000000550. 



Cigarette Smoking Is Significantly Linked to Sexual Dissatisfaction in Chinese Heroin-Dependent Patients Receiving Methadone Maintenance Treatment.

Zhong BL, Xu YM, Xie WX, Lu J.

Front Psychiatry. 2019 May 22;10:306. doi: 10.3389/fpsyt.2019.00306.


Loneliness and Illicit Opioid Use Among Methadone Maintenance Treatment Patients.

Polenick CA, Cotton BP, Bryson WC, Birditt KS.

Subst Use Misuse. 2019 Jun 24:1-10. doi: 10.1080/10826084.2019.1628276. 



Functional Correlates of Resting-State Connectivity in the Default Mode Network of Heroin Users on Methadone Treatment and Medication-Free Therapeutic Community Program.

Kuo LW, Lin PS, Lin SY, Liu MF, Jan H, Lee HC, Wang SC.

Front Psychiatry. 2019 Jun 6;10:381. doi: 10.3389/fpsyt.2019.00381. 


Double-Blind Placebo-Controlled Trial of Galantamine for Methadone-Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use.

Carroll KM, DeVito EE, Yip SW, Nich C, Sofuoglu M.

Am J Addict. 2019 Jun 4. doi: 10.1111/ajad.12904.



Ginseng treatment improves the sexual side effects of methadone maintenance treatment.

Farnia V, Alikhani M, Ebrahimi A, Golshani S, Sadeghi Bahmani D, Brand S.

Psychiatry Res. 2019 May 2;276:142-150. doi: 10.1016/j.psychres.2019.05.004. 



Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men.

Agha-Mohammadhasani P, Mokhtaree M, Nazari A, Rahnama A.

Addict Health. 2018 Apr;10(2):76-85. doi: 10.22122/ahj.v10i2.540.


Craving for heroin: difference between methadone maintenance therapy patients with and without ADHD.

Coppola M, Sacchetto G, Mondola R.

Trends Psychiatry Psychother. 2019 Jan-Mar;41(1):83-86. doi: 10.1590/2237-6089-2017-0159.


Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.

Ward HB, Barnett BS, Suzuki J.

Subst Abus. 2019 Mar 19:1-6. doi: 10.1080/08897077.2019.1573776.



Relevance of CYP2B6 and CYP2D6 genotypes to methadone pharmacokinetics and response in the OPAL study.

Victorri-Vigneau C, Verstuyft C, Bouquié R, Laforgue EJ, Hardouin JB, Leboucher J, Le Geay B, Dano C, Challet-Bouju G, Grall-Bronnec M.

Br J Clin Pharmacol. 2019 Mar 25. doi: 10.1111/bcp.13936. 



A Pilot Crossover Trial of Sleep Medications for Sleep-disturbed Methadone Maintenance Patients.

Stein MD, Kurth ME, Anderson BJ, Blevins CE.

J Addict Med. 2019 Mar 9. doi: 10.1097/ADM.0000000000000531. 



Effects of Methadone Maintenance Therapy on Thyroid Function of Adult Men.

Bozchelou S, Delirrad M.

Toxicol Res. 2019 Jan;35(1):9-12. doi: 10.5487/TR.2019.35.1.009. 


Initiation and Rapid Titration of Methadone in an Acute Care Setting for the Treatment of Opioid Use Disorder: A Case Report.

Hemmons P, Bach P, Colizza K, Nolan S.

J Addict Med. 2019 Feb 5. doi: 10.1097/ADM.0000000000000507.



Comparing opium tincture and methadone for medication-assisted treatment of patients with opioid use disorder: Protocol for a multicenter parallel group noninferiority double-blind randomized controlled trial.

Nikoo M, Moazen-Zadeh E, Nikoo N, Javidanbardan S, Kazemi A, Choi F, Vogel M, Gholami A, Tavakoli S, Givaki R, Jazani M, Mohammadian F, Markazi Moghaddam N, Goudarzi N, Schutz C, Jang K, Akhondzadeh S, Krausz M.

Int J Methods Psychiatr Res. 2019 Feb 4:e1768. doi: 10.1002/mpr.1768. 



Intravenous Misuse of Methadone, Buprenorphine and Buprenorphine-Naloxone in Patients Under Opioid Maintenance Treatment: A Cross-Sectional Multicentre Study.

Lugoboni F, Zamboni L, Cibin M, Tamburin S; Gruppo InterSERT di Collaborazione Scientifica (GICS).

Eur Addict Res. 2019;25(1):10-19. doi: 10.1159/000496112. 



Methadone Safety: A Clinical Practice Guideline From the American Pain Society and College on Problems of Drug Dependence, in Collaboration With the Heart Rhythm Society

Chou, Roger et al.

The Journal of Pain , Volume 15 , Issue 4 , 321 - 337 


Methadone therapy modulate the dendritic cells of heroin addicts.

Akbari A, Mosayebi G, Samiei AR, Ghazavi A.

Int Immunopharmacol. 2019 Jan;66:330-335. doi: 10.1016/j.intimp.2018.11.047.



Safe and Appropriate Use of Methadone in Hospice and Palliative Care: Expert Consensus White Paper.

McPherson ML, Walker KA, Davis MP, Bruera E, Reddy A, Paice J, Malotte K, Lockman DK, Wellman C, Salpeter S, Bemben NM, Ray JB, Lapointe BJ, Chou R.

J Pain Symptom Manage. 2018 Dec 19. pii: S0885-3924(18)31114-X. doi: 10.1016/j.jpainsymman.2018.12.001.



Clinical experience with methadon.


Anesthesiology. 1948 Nov;9(6):585-93. 


Can Methadone Lower Viral Loads?

A study presented at the 22nd International AIDS Conference in Amsterdam demonstrated that methadone maintenance treatment (MMT) is associated with less time spent with a high viral load. The results are based on data from the AIDS Care Cohort to Evaluate Exposure to Survival Services in Vancouver, Canada. (hivplusmag.com, USA, 26.12.2018)


Injection opioid use as a predictor of treatment outcomes amog methadone-maintained opioid-dependent patients.

Ledgerwood DM, Lister JJ, LaLiberte B, Lundahl LH, Greenwald MK.

Addict Behav. 2018 Oct 31;90:191-195. doi: 10.1016/j.addbeh.2018.10.046. 



A clinical trial on the acute effects of methadone and buprenorphine on actual driving and cognitive function of healthy volunteers. 

Strand, M. C., Vindenes, V., Gjerde, H., Mørland, J. G., and Ramaekers, J. G. (2018) 

Br J Clin Pharmacol, doi.org/10.1111/bcp.13818


Methadone maintenance treatment as social control: Analyzing patient experiences.

O'Byrne P, Jeske Pearson C.

Nurs Inq. 2018 Nov 20:e12275. doi: 10.1111/nin.12275. 



Predictors of sleep disturbance in heroin users receiving methadone maintenance therapy: a naturalistic study in Taiwan.

Li DJ, Chung KS, Wu HC, Hsu CY, Yen CF.

Neuropsychiatr Dis Treat. 2018 Oct 26;14:2853-2859. doi: 10.2147/NDT.S177370.


Methadone Dosage and Plasma Levels, SNPs of OPRM1 Gene and Age of First Drug Use Were Associated With Outcomes of Methadone Maintenance Treatment.

Peng S, Jiang H, Du J, Lin S, Pan S, Yu S, Zhao M.

Front Genet. 2018 Oct 29;9:450. doi: 10.3389/fgene.2018.00450. 


Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone.

Webster LR, Israel RJ.

J Pain Res. 2018 Oct 23;11:2509-2516. doi: 10.2147/JPR.S160625.


Einleitung einer Substitutionsbehandlung mit Buprenorphin unter vorübergehender Überlappung mit Heroinkonsum: ein neuer Ansatz („Berner Methode”)

Induction of a Buprenorphine Substitution Treatment with Temporary Overlap of Heroin Use: A New Approach (“Bernese Method”)R. Hämmig

Suchttherapie 2010; 11(3): 129-132, DOI: 10.1055/s-0030-1261914



Methadone to buprenorphine/naloxone induction without withdrawal utilizing transdermal fentanyl bridge in an inpatient setting-Azar method.

Azar P, Nikoo M, Miles I.

Am J Addict. 2018 Nov 2. doi: 10.1111/ajad.12809. 



Integrated, Co-located, Telemedicine-based Treatment Approaches for Hepatitis C Virus (HCV) Management in Opioid Use Disorder Patients on Methadone.

Talal AH, Andrews P, Mcleod A, Chen Y, Sylvester C, Markatou M, Brown LS.

Clin Infect Dis. 2018 Oct 17. doi: 10.1093/cid/ciy899.