Kanada. Canada’s Methadone Prescribing Changes With Drug Supply Canadian physicians have responded to recent guidelines suggesting an increase in methadone initiation dosages in unexposed patients, especially those using fentanyl. Still, substantia…

Methadone treatment for people who use fentanyl: Recommendations.  Bromley L, Kahan M, Regenstreif L, Srivastava A, Wyman J.  Toronto, ON: META:PHI; 2021. www.metaphi.ca., Version date: 30 June 2021 https://www.metaphi.ca/wp-content/upl…

Accidental Methadone Toxicity in a 3-Year-Old Leading to Severe Cerebellitis and Death: A Case Report.  Pappin J, Hansen G, Holt T.  Case Rep Pediatr. 2025 Jul 10;2025:1045330. doi: 10.1155/crpe/1045330. PMID: 40686917; PMCID: PMC1227170…

Methadone-Induced Toxicity - An Unexpected Challenge for the Brain and Heart in ICU Settings: Case Report and Review of the Literature.  Cristina BG, Isac S, Teodorescu GD, Isac T, Martac C, Cobilinschi C, Pavel B, Andreescu CV, Droc G. …

Cognitive functioning in subjects with Substance Use Disorder: retrospective observational study on the transition from Methadone to Levomethadone Silvia Pinna, Giuseppe Gagliardo, Selene Regio, Francesca Pagliari, Lorenzo Finocchiaro, Maria Cristi…

Association of ABCB1, μ-opioid Receptor, and Cytochrome P450 Genes with Methadone Dose in Iranian Male Addicts Under Methadone Therapy.  Golnezhad A, Torkaman-Boutorabi A, Mohammad Razaghi E, Zarrindast MR, Mahdavi MR, Vousooghi…