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USA. JUUL laboratories have largest market share of E-cigarettes

(HealthDay)—From 2016 to 2017, sales of electronic cigarettes (e-cigarettes) by JUUL Laboratories increased 641 percent, with their sales comprising 29 percent of total e-cigarette sales by December 2017, according to a research letter published in the Oct. 2 issue of the Journal of the American Medical Association. (medicalxpress.com, USA, 04.10.2018)

https://medicalxpress.com/news/2018-10-juul-laboratories-largest-e-cigarettes.html

High stakes: cannabis capitalists seek funds to drive drug trade - London conference pushes uses ranging from reducing pain to increasing orgasms

(...) The global cannabis industry has gathered in London this week for Europe’s largest marijuana investment conference, Cannabis Invest, with bosses of industrial-scale weed growers hoping to tap UK investors for fresh funds to drive expansion plans. (The Guardian, UK, 03.10.2018)

https://www.theguardian.com/business/2018/oct/03/high-stakes-cannabis-capitalists-seek-funds-to-drive-drug-trade

Science without publication paywalls: cOAlition S for the realisation of full and immediate Open Access.

Schiltz M (2018) 

PLoS Biol 16(9): e3000031. https://doi.org/10.1371/journal.pbio.3000031

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002663

USA. High-Nicotine E-Cigarettes Flood Market Despite FDA Rule

The sleek Juul electronic cigarettes have become a phenomenon at U.S. high schools, vexing educators and drawing regulatory scrutiny over their sweet flavors and high nicotine content. (Medscape, 26.09.2018)

https://www.medscape.com/viewarticle/902394

USA. As opioid crisis rages, cost of overdose antidote spikes

As the opioid epidemic continues to kill tens of thousands of Americans each year, the drug naloxone has proved invaluable in preventing overdose-related deaths. Yet a spike in its cost in recent years has constrained access to naloxone, potentially depriving health care professionals, emergency responders and families of a critical treatment than can save lives. (CBS-News, Money Watch, USA, 14.08.2018)

https://www.cbsnews.com/news/as-opioids-kill-more-americans-cost-of-overdose-antidote-spikes/

USA. OxyContin maker gets patent for drug to treat opioid addiction

Purdue Pharma, the maker of OxyContin, has received a patent designed to treat opioid addiction.

The patent, first reported by The Financial Times, is for a new and faster-acting form of buprenorphine. (CBS-News, Money Watch, USA, 07.08.2018)

https://www.cbsnews.com/news/oxycontin-maker-receives-patent-for-drug-to-treat-opioid-addiction/

USA. L'Oréal urged to rebrand 'breathtakingly insensitive' Black Opium fragrance by anti-drug group 

The National Council Against Drug Abuse accuses the beauty giant of "the height of cruelty" by attempting to profit while people are losing their lives to real opium. (Cosmetic Business, USA, 21.09.2018)

https://www.cosmeticsbusiness.com/news/article_page/LOral_urged_to_rebrand_breathtakingly_insensitive_Black_Opium_fragrance_by_antidrug_group/147332

Deutschland. Milliardeneinnahmen durch legales Cannabis: Kiffen für den Fiskus 

In Kanada gibt es ab Mitte Oktober legales Cannabis zu kaufen. Was würde eine Freigabe für die deutsche Volkswirtschaft bedeuten? Einer Studie zufolge könnte die Staatskasse ein Milliardenplus verbuchen. (Spiegel online, 24.09.2018)

http://www.spiegel.de/wirtschaft/soziales/deutschland-cannabis-legalisierung-koennte-milliarden-bringen-a-1224770.html

Cola mit Cannabis? Aurora-Aktionäre im Rausch - Coca-Cola signalisiert Interesse 

Ein Medienbericht über das mögliche Interesse von Coca-Cola hat Anleger des kanadischen Marihuana-Herstellers Aurora Cannabis in einen Kaufrausch versetzt. (Manager Magazin, 18.09.2018)

http://www.manager-magazin.de/unternehmen/handel/coca-cola-mit-cannabis-aurora-aktie-steigt-nach-spekulationen-ueber-einstieg-a-1228675.html

USA/Kanada. Joint venture: Coca-Cola considers cannabis-infused range 

Soft drink maker in talks with Canadian marijuana producer about beverages to ease pain. (The Guardian, UK, 17.09.201)

https://www.theguardian.com/business/2018/sep/17/joint-venture-drinks-giant-coca-cola-mulls-cannabis-infused-range

USA. Insurer To Purdue Pharma: We Won’t Pay For OxyContin Anymore

The largest insurer in Tennessee has announced it will no longer cover prescriptions for what was once a blockbuster pain reliever. It’s the latest insurance company to turn against OxyContin, whose maker, Purdue Pharma, faces dozens of lawsuits related to its high-pressure sales tactics around the country and contribution to the opioid crisis. (Kaiser Health News, USA, 13.09.2018)

https://khn.org/news/insurer-to-purdue-pharma-we-wont-pay-for-oxycontin-anymore

Patent auf Hepatitis-Medikament bleibt mit Änderungen

München – Das US-Pharma-Unternehmen Gilead darf sein umstrittenes Patent auf ein Hepatitis-C-Medikament behalten – allerdings mit Änderungen. Das hat das Europäische Patentamt heute in München entschieden. Ärzte ohne Grenzen und Ärzte der Welt scheiterten demnach weitgehend mit ihrem Versuch, das Patent auf den Wirkstoff Sofosbuvir aufheben zu lassen. (aerzteblatt.de, 13.09.2018)

https://www.aerzteblatt.de/nachrichten/97876/Patent-auf-Hepatitis-Medikament-bleibt-mit-Aenderungen

USA. OxyContin Billionaire Patents New Drug for Opioid Treatment

In recent years, America’s pharmaceutical industry has taken it on the chin. Populist demagogues have savaged drug companies for “jacking up” the price of life-saving substances like insulin (a.k.a. honoring their fiduciary duty to maximize shareholder value). These boisterous neo-Bolsheviks will point to the fact that pharmaceuticals are several times more expensive in the U.S. than in other countries, and conclude that our government’s exceptionally strong patent laws — and aberrant refusal to push down drug prices through direct negotiation — are meant to enrich Big Pharma at the working American’s expense. (Daily Intelligencer, USA, 07.09.2018)

http://nymag.com/daily/intelligencer/2018/09/richard-sackler-oxycontin-billionaire-patent-opioid-addiction-treatment-buprenorphine.html

Kanada. Kanadische Provinz verklagt Unternehmen wegen Opioid-Überdosen

Ottawa – Angesichts des grassierenden Missbrauchs von Opioiden hat die kanadische Provinz British Columbia mehr als 40 Hersteller und Vertreiber der Schmerzmittel auf Schadenersatz verklagt. Bei der ersten derartigen Klage von kanadischen Behörden gehe es um die Erstattung der Kosten von Notarzteinsätzen und Kranken­ausaufenthalten wegen Opioid-Überdosen, teilte der Justizminister der westkanadischen Provinz, David Eby, mit. Beschuldigt werden Hersteller, Großhändler und Vertreiber der starken Schmerzmittel. (aerzteblatt.de, 30.08.2018)

https://www.aerzteblatt.de/nachrichten/97519/Kanadische-Provinz-verklagt-Unternehmen-wegen-Opioid-Ueberdosen

USA. Purdue And The OxyContin Files

Purdue Pharma planned an extensive marketing campaign for the launch and promotion of the painkiller OxyContin. Here are Purdue’s internal budget documents from 1996 to 2002 — files released by the Florida attorney general’s office — that detail the company’s early strategy to sell and expand use of the drug. (Kaiser Health News, 13.06.2018)

https://khn.org/news/purdue-and-the-oxycontin-files/

Major tobacco companies found to be secretly using influencers to advertise

Tobacco companies are secretly advertising cigarettes on social media platforms such as Instagram, Facebook and Twitter by paying social media influencers to post images of cigarettes and smoking as part of a marketing strategy. The social media campaigns have been documented in countries that ban tobacco advertising on the internet. These campaigns also circumvent  the policies of social media companies like Facebook and Instagram that do not allow paid advertising for tobacco products on their platforms. (marketing-interactive.com, 28.08.2018)

https://www.marketing-interactive.com/major-tobacco-companies-found-to-be-secretly-using-influencers-to-advertise/

Medizinalhanf. Deutschland importiert mehr Cannabis aus den Niederlanden

Die Nachfrage nach medizinischem Cannabis in Deutschland ist deutlich größer als erwartet. Nach SPIEGEL-Informationen haben die Niederlande jetzt zugesagt, künftig bis zu 1,5 Tonnen pro Jahr zu liefern. (spiegel.de, 24.08.2018)

http://www.spiegel.de/gesundheit/diagnose/deutschland-importiert-mehr-medizinisches-cannabis-aus-den-niederlanden-a-1224736.html

Wem gehören die Cannabis-Firmen?

Nach einer aktuellen Pressemitteilung firmiert die Pedanios GmbH Deutschland nunmehr als Aurora GmbH. Auch bei vielen anderen Firmen hat es Übernahmen sowie Fusionen und damit Konzentrationen auf wenige große Cannabisfirmen gegeben.

Mittlerweile wird der deutsche (und internationale) Markt für Medizinalcannabis nur noch von vier Unternehmen bzw. Dachgesellschaften dominiert. Daneben gibt es noch einige kleinere Firmen. Die großen Firmen sind:

- Bedrocan International als einziger niederländischer Hersteller. Sie haben ihren Lizenzvertrag mit Canopy Growth, denen Bedrocan Canada gehört hatte, dieses Jahr beendet.
- Canopy Growth Corporation gehören die kanadischen Hersteller Tweed und Spectrum Cannabis, deren Produkte von Spektrum Cannabis als deutsche Niederlassung importiert werden.
- Aurora Cannabis gehören die kanadischen Hersteller Pedanios, MedReleaf und CanniMed.
- Cronos Group gehören die kanadischen Hersteller Peace Naturals, Original BC und Whistler Medical Marijuana Company.

Alle anderen Unternehmen in Deutschland sind Importeure. Aphria und Mericann möchten den deutschen Markt noch dieses Jahr über ihre Tochterunternehmen beliefern. Privateer Holdings gehört Leafly und Tilray. Tilray beliefert den deutschen Markt bisher mit zwei Cannabisextrakten. (IACM, 25.08.2018)

http://www.cannabis-med.org/german/acm-mitteilungen/ww_de_db_cannabis_artikel.php?id=268#2

USA. Firms stop kid-friendly packaged e-cigarette liquids sales after FDA push

The U.S. Food and Drug Administration said on Thursday that all 17 companies that were warned by the regulator have stopped marketing e-cigarette liquids packaged similar to child-friendly products such as juice boxes, candy or cookies. (Reuters, 23.08.2018)

https://uk.reuters.com/article/us-fda-tobacco/firms-stop-kid-friendly-packaged-e-cigarette-liquids-sales-after-fda-push-idUKKCN1L824T

UK. US multinational buys into UK rehab centres as demand grows 

Eli Global invests in private clinics amid fears of shortage of publicly funded facilities.

The UK private rehab market is set to grow exponentially, one of the largest addiction firms in the country has said after receiving US investment. (The Guardian, 17.08.2018)

https://www.theguardian.com/society/2018/aug/17/us-multinational-buys-into-uk-rehab-centres-as-demand-grows

Cigarette brand diversity and price changes during the implementation of plain packaging in the United Kingdom.

Breton, M. O., Britton, J., Huang, Y., and Bogdanovica, I. (2018

Addiction, doi.org/10.1111/add.14282

https://onlinelibrary.wiley.com/doi/10.1111/add.14282

USA. Purdue Pharma’s Sales Pitch Downplayed Risks Of Opioid Addiction

Two decades ago, Purdue Pharma produced thousands of brochures and videos that urged patients with chronic pain to ask their physicians for opioids such as OxyContin, arguing that concerns over addiction and other dangers from the drugs were overblown, company records reveal.

(...)

More than 1,500 pending civil lawsuits, filed mostly by state and local governments, allege that deceptive marketing claims helped fuel a national epidemic of opioid addiction and thousands of overdose deaths.

This week, the New York attorney general’s office filed another suit that accuses Purdue of operating a “public nuisance” in it sales tactics and marketing of opioids. Like many others, the suit demands compensation for addiction treatment costs and other problems. Purdue and other drugmakers have denied all allegations. (Kaiser Health News, 17.08.2018)

https://khn.org/news/purdue-pharma-sales-pitch-downplayed-risks-of-opioid-addiction

Corona beer owner to pour $4bn into weed

Corona beer owner Constellation Brands is set to pour some $4bn (£3.15bn) into Canada's top cannabis producer, Canopy Growth, in a deal marking the largest investment in the industry to date. (BBC, 16.08.2018)

https://www.bbc.co.uk/news/business-45204186

USA. U.S. joins lawsuits against Indivior, Reckitt over drug Suboxone

Reckitt Benckiser Group PLC, alleging that the drugmakers improperly marketed the opioid addiction treatment Suboxone. (Reuters, 08.08.2018)

https://www.reuters.com/article/us-indivior-lawsuit/u-s-joins-lawsuits-against-indivior-reckitt-over-drug-suboxone-idUSKBN1KT2NW

USA. How Rival Opioid Makers Sought To Cash In On Alarm Over OxyContin’s Dangers

As Purdue Pharma faced mounting criticism over deaths linked to OxyContin, rival drugmakers saw a chance to boost sales by stepping up marketing of similarly dangerous painkillers, such as fentanyl, morphine and methadone, Purdue internal documents reveal. (Kaiser Health News, USA, 02.08.2018)

https://khn.org/news/how-rival-opioid-makers-sought-to-cash-in-on-alarm-over-oxycontins-dangers

USA. Bipartisan leaders of House panel press drug companies on opioid crisis 

Bipartisan leaders of the House Energy and Commerce Committee are pressing three drug companies for answers about their role in the opioid crisis. (The Hill, USA, 03.08.2018)

http://thehill.com/policy/healthcare/400233-bipartisan-house-panel-presses-drug-companies-on-role-in-opioid-crisis

CDU-Abgeordnete kritisieren Kauders Blockadehaltung gegen Tabakwerbeverbot

Frankfurt am Main – Unionsabgeordnete im Bundestag haben Fraktionschef Volker Kauder (CDU) aufgefordert, seine Blockadehaltung für ein Tabakwerbeverbot aufzugeben. „Wir machen uns als deutsche Befürworter eines globalen Gesundheitsschutzes lächerlich, wenn wir das Tabakwerbeverbot nicht endlich auf die Reihe kriegen“, sagte der CDU-Abgeordnete Rudolf Henke, der auch Vorstandsmitglied der Bundesärztekammer ist, der Frankfurter Allgemeinen Sonntagszeitung (FAS). (aerzteblatt.de, 30.07.2018)

https://www.aerzteblatt.de/nachrichten/96774/CDU-Abgeordnete-kritisieren-Kauders-Blockadehaltung-gegen-Tabakwerbeverbot

USA. Purdue Pharma Edits Public Service Ad In Washington Post

In a new public service ad, drugmaker Purdue Pharma suggested that taking opioids such as its painkiller OxyContin even as prescribed can prove dangerous — then appeared to backtrack a few days later.

“We are acutely aware of the public health risks opioid analgesics can create, even when taken as prescribed,” Purdue wrote in a full-page advocacy ad published July 19 in The Washington Post.

But a version of the same ad published in the July 24 Washington Post omits the words “even when taken as prescribed.” The ad is otherwise identical. (KHN – Kaiser Health News, 24.07.2018)

https://khn.org/news/purdue-pharma-edits-public-service-ad-in-washington-post

Supermärkte dürfen Schockbilder von Zigarettenpackungen an Ladenkasse verdecken

München – Das Münchner Landgericht hat ein Urteil mit Signalwirkung für Tabakin­dustrie und Einzelhandel gesprochen: Supermärkte müssen die Schockbilder auf Zigarettenschachteln an der Ladenkasse nicht sämtlichen Kunden präsentieren, sondern dürfen diese im Verkaufsautomaten verdecken. (aerzteblatt.de, 05.07.2018)

https://www.aerzteblatt.de/nachrichten/96267/Supermaerkte-duerfen-Schockbilder-von-Zigarettenpackungen-an-Ladenkasse-verdecken

USA. Opioid Makers, Blamed for Overdose Epidemic, Cut Back on Marketing Payments to Doctors

The past two years have been a time of reckoning for pharmaceutical manufacturers over their role in promoting opioid drugs that have fed a national epidemic.

Lawsuits and media reports have accused Purdue Pharma, the maker of OxyContin, of aggressively marketing the powerful narcotic even after it knew the drug was being misused. Prosecutors have charged the founder of Insys Therapeutics and several of the company’s sales representatives and executives for their roles in an alleged conspiracy to bribe doctors to use its fentanyl spray for unapproved uses. State and local governments have sued a host of drugmakers, alleging they deceptively marketed opioids and seeking to recoup what it costs to treat people addicted to the drugs. (MedScape, 07.07.2018)

https://www.medscape.com/viewarticle/898784