Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone'.  Pappagallo M, Kosten TR, Gorodetzky CW, Vocci FJ, Sapienza FL, De Martin S, Comai S, Mattarei A, Inturri…

Questioning methadone split-dosing for analgesia among hospitalized patients with opioid use disorder.  Terasaki D, Abts D, Ferraro K.  Addiction. 2024 Apr 14. doi: 10.1111/add.16502. Epub ahead of print. PMID: 38615677. https://onlinel…

Evaluation of Serum Cortisol Levels and Response to Cosyntropin Test in Methadone-treated Opium Addicts.  Zojaji F, Khalesi A, Bahrami A, Ebrahimi SA, Ganjifard M.  Anesth Pain Med. 2023 Jun 3;13(3):e135206. doi: 10.5812/aapm-135206. PMI…

Mediating effect of craving on the impact of buprenorphine/naloxone and methadone treatment on opioid use: Results from a randomized controlled trial.  McAnulty C, Bastien G, Ledjiar O, Eugenia Socias M, Le Foll B, Lim R, Jutras-Aswad D; OPTIM…

The IMPOWR Network Divided or Single Exposure Study (DOSE) Protocol: A Randomized Controlled Comparison of Once Versus Split Dosing of Methadone for the Treatment of Comorbid Chronic Pain and Opioid Use Disorder.  McKendrick G, Davis W, Sklar…

Severe cerebral edema related to oral methadone: A case report and literature review.  Cañas CA, Posso-Osorio I, Rivera-Londoño R, Bolaños JD, Granados AM.  Heliyon. 2024 Feb 13;10(4):e26111. doi: 10.1016/j.heliyon.2024.e26111. PMID…