| Hans-Günter Meyer-Thompson | Methadon zur Substitution
Variation in the Gene for the μ-Opioid Receptor May Influence Responses to Methadone
Variation in the Gene for the μ-Opioid Receptor May Influence Responses to Methadone
This study found that:
A single nucleotide polymorphism (SNP) in the messenger RNA of the µ-opioid receptor gene was associated with patients’ responses to methadone treatment for opioid dependence.
The association may occur because one variant of the SNP produces fewer µ-opioid receptors than the alternate form. (NIDA Notes, By William Ross Perlman, Ph.D., CMPP, 23.08.2017)