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Mom's use of opioids in pregnancy may stunt kids' learning

Learning disabilities and other special education needs are common in children born with opioid-related symptoms from their mother's drug use while pregnant, according to the first big U.S. study to examine potential long-term problems in these infants. 

About 1 in 7 affected children required special classroom services for problems including developmental delays and speech or language difficulties, compared with about 1 in 10 children not exposed to opioids before birth, the study found. (MedicalXpress, USA, 30.08.2018)

https://medicalxpress.com/news/2018-08-mom-prenatal-opioids-stunt-kids.html

USA. AAP Raises Concerns About Increasing Marijuana Use During Pregnancy and Breastfeeding

Itasca, IL - With marijuana use more commonly reported by women who are pregnant or breastfeeding, a new American Academy of Pediatrics (AAP) report calls for more research on possible developmental effects on children. Highlighting emerging evidence that marijuana likely is not harmless as widely assumed, the AAP recommends women avoid the drug while pregnant or nursing a child. (American Academy of Pediatrics, 27.08.2018)

https://www.aap.org/en-us/about-the-aap/aap-press-room/Pages/AAP-Raises-Concerns-About-Increasing-Marijuana-Use-During-Pregnancy-and-Breastfeeding.aspx

Cannabis: THC noch nach sechs Tagen in der Brustmilch nachweisbar

San Diego – Die psychoaktive Substanz Tetrahydrocannabinol (THC) war in einer Studie in Pediatrics (2018; doi: 10.1542/peds.2018-1076) bei stillenden Frauen, die Cannabis konsumiert hatten, noch bis zu 6 Tage in der Muttermilch nachweisbar. (aerzteblatt.de, 29.08.2018)

https://www.aerzteblatt.de/nachrichten/97491/Cannabis-THC-noch-nach-sechs-Tagen-in-der-Brustmilch-nachweisbar

Schweiz. Broschüre "Schwangerschaft und Alkohol,Schwangerschaft und Tabak: Gut zu wissen", in 9 Sprachen. Informationen für werdende Mütter, Frauen mit Kinderwunsch, Väter sowie Nahestehende.

Sprachen: Deutsch, Französisch, Italienisch, Albanisch, Englisch, Spanisch, Portugiesisch, Serbisch/Kroatisch/Bosnisch, Türkisch

Sucht Schweiz, Lausanne, 2016

https://shop.addictionsuisse.ch/de/home/627-schwangerschaft-und-alkohol-schwangerschaft-und-tabak-.html

Drugs and Lactation Database (LactMed) 

What is LactMed?

The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Suggested therapeutic alternatives to those drugs are provided, where appropriate. All data are derived from the scientific literature and fully referenced. A peer review panel reviews the data to assure scientific validity and currency.

Updates: LactMed is updated monthly.

https://toxnet.nlm.nih.gov/newtoxnet/lactmed.htm

Treatment modalities for pregnant women with opioid use disorder

Laura E Gressler, Doris Titus-Glover, Fadia Tohme Shaya

The Lancet, Volume 392, ISSUE 10147, P551, August 18, 2018doi.org/10.1016/S0140-6736(18)31471-5

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31471-5/fulltext

Stabilizing the Mother-Infant Dyad for Better Outcomes from OB to FM: Caring for Patients with Perinatal Opioid Use Disorder through the 4th Trimester.

Ramage M, Ostrach B, Fagan B, Coulson CC.

N C Med J. 2018 May-Jun;79(3):164-165. doi: 10.18043/ncm.79.3.164. 

http://www.ncmedicaljournal.com/content/79/3/164.long

Heroin - Drugs and Lactation Database 

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Last Revision: May 1, 2018.

https://www.ncbi.nlm.nih.gov/books/NBK500783/

Methadone - Drugs and Lactation Database.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Last Revision: June 4, 2018.

https://www.ncbi.nlm.nih.gov/books/NBK501233/

Buprenorphine - Drugs and Lactation Database

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Last Revision: June 4, 2018.

https://www.ncbi.nlm.nih.gov/books/NBK501202/

Study analyzes opioid overdose risk during and after pregnancy among Massachusetts women 

Overdose risk drops during pregnancy but rises after delivery, when fewer resources are available to mothers with substance use disorder. (Massachusetts General Hospital, 11.07.2018)

https://www.eurekalert.org/pub_releases/2018-07/mgh-sao071118.php

Psychotic due to bath salts and methamphetamines: emergency cesarean section under general anesthesia.

Nina S.

J Biomed Res. 2018 Jul 2. doi: 10.7555/JBR.32.20180023. 

http://www.jbr-pub.org.cn/uploadfile/JBR-2018-0023.pdf

Buprenorphine/naloxone in the Treatment of Opiate Dependency during Unintentional Pregnancies - Bosnia-Herzegovina Experiences.

Hasanović M, Pajević I, Kuldija A, Delić A, Hrvić D.

Psychiatr Danub. 2018 Jun;30(2):230-232. 

http://www.hdbp.org/psychiatria_danubina/pdf/dnb_vol30_no2/dnb_vol30_no2_230.pdf

Gestational changes in buprenorphine exposure: A physiologically-based pharmacokinetic analysis.

Zhang H, Kalluri HV, Bastian JR, Chen H, Alshabi A, Caritis SN, Venkataramanan R.

Br J Clin Pharmacol. 2018 Jun 5. doi: 10.1111/bcp.13642.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29873094

The Pregnancy Recovery Center: A women-centered treatment program for pregnant and postpartum women with opioid use disorder.

Krans EE, Bobby S, England M, Gedekoh RH, Chang JC, Maguire B, Genday P, English DH.

Addict Behav. 2018 May 24. pii: S0306-4603(18)30529-X. doi: 10.1016/j.addbeh.2018.05.016.

Abstract

https://www.sciencedirect.com/science/article/abs/pii/S030646031830529X

Does Maternal Buprenorphine Dose Affect Severity or Incidence of Neonatal Abstinence Syndrome?

Wong J, Saver B, Scanlan JM, Gianutsos LP, Bhakta Y, Walsh J, Plawman A, Sapienza D, Rudolf V.

J Addict Med. 2018 Jun 13. doi: 10.1097/ADM.0000000000000427.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29905586

Substance Use in Pregnant Women Using the Emergency Department: Undertested And Overlooked?

Moyer CL, Johnson S, Klug MG, Burd L.

West J Emerg Med. 2018 May;19(3):579-584. doi: 10.5811/westjem.2018.1.35630.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942028/

Treating Opioid Use Disorder During Pregnancy

(National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services, Juli 2017)

https://www.drugabuse.gov/publications/treating-opioid-use-disorder-during-pregnancy/treating-opioid-use-disorder-during-pregnancy

Berlin. Facilities for pregnant women with drug use history in Berlin (Video)

Our new film features the story of Netti, her son Sam, and their experience with services for pregnant women who use drugs in Berlin. (Drug Reporter, Ungarn, Video, 15:20)

https://www.youtube.com/watch?v=frNIB4TxGcI&t=5s

National, regional, and global prevalence of smoking during pregnancy in the general population: a systematic review and meta-analysis

Lange, Shannon et al.

The Lancet Global Health , Volume 0 , Issue 0 , Published: 30 May 2018, doi.org/10.1016/S2214-109X(18)30223-7

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30223-7/fulltext

A global perspective on smoking during pregnancy

Siddiqi, Kamran et al.

The Lancet Global Health , Volume 0 , Issue 0 , Published: 30 May 2018, doi.org/10.1016/S2214-109X(18)30246-8

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30246-8/fulltext

Symptoms Associated With Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorders in School-Aged Children Prenatally Exposed to Substances.

Sandtorv LB, Fevang SKE, Nilsen SA, Bøe T, Gjestad R, Haugland S, Elgen IB.

Subst Abuse. 2018 Mar 22;12:1178221818765773. doi: 10.1177/1178221818765773. eCollection 2018.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871041/

Psychological Functioning of Women Taking Illicit Drugs during Pregnancy and the Growth and Development of Their Offspring in Early Childhood.

Serino D, Peterson BS, Rosen TS.

J Dual Diagn. 2018 Apr 25:0. doi: 10.1080/15504263.2018.1468946.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29694295

Examination of Hospital, Maternal, and Infant Characteristics Associated with Breastfeeding Initiation and Continuation Among Opioid-Exposed Mother-Infant Dyads.

Schiff DM, Wachman EM, Philipp B, Joseph K, Shrestha H, Taveras EM, Parker MGK.

Breastfeed Med. 2018 Apr 9. doi: 10.1089/bfm.2017.0172.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29630387

PREGNANCY& OPIOIDS: What families need to know about opioid misuse and treatment during pregnancy

If there a young woman in your life who is pregnant and misusing or addicted to opioids, it is possible to obtain treatment and reduce the risks in order to have a healthy pregnancy and a healthy baby. (drugfree org, Mai 2018)

https://drugfree.org/download/pregnancy-opioids/

The Use of Serum Methadone/Metabolite Ratios to Monitor Changing Perinatal Pharmacokinetics.

McCarthy JJ, Vasti EJ, Leamon MH, Graas J, Ward C, Fassbender C.

J Addict Med. 2018 Mar 7. doi: 10.1097/ADM.0000000000000398.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29521669

Barriers and Facilitators of Breastfeeding Reported by Postpartum Women in Methadone Maintenance Therapy.

Hicks J, Morse E, Wyant DK.

Breastfeed Med. 2018 Mar 29. doi: 10.1089/bfm.2017.0130.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29595995

Management of eight labor and delivery patients dependent on buprenorphine (Subutex™): A retrospective chart review.

Tith S, Bining G, Bollag L.

Version 2. F1000Res. 2018 Jan 3 [revised 2018 Jan 1];7:7. doi: 10.12688/f1000research.13350.2.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820592/

Behandlung substituierter Frauen während Schwangerschaft und Geburt - Ein Informationspapier für  Gynäkologen, Pädiater und Hebammen

Erbas B, Huber G, Tretter F und Wolstein J

BAS – Bayerische Akademie für Sucht- und Gesundheitsfragen (Stand September 2014)

https://www.bas-muenchen.de/fileadmin/documents/pdf/Publikationen/Papiere/BAS_UG_Informationspapier_Behandlung_Substituierter_Schwangerschaft_Geburt_Sept_2014.pdf

Cigarette Smoking Reduction in Pregnant Women With Opioid Use Disorder.

Ram A, Tuten M, Chisolm MS.

J Addict Med. 2016 Jan-Feb;10(1):53-9. doi: 10.1097/ADM.0000000000000186.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733574/