Risks associated with combining Bufo Alvarius with ayahuasca
Recently the use of the secretions of by the Bufo Alvarius toad (correct name Incilius alvarius) has become popular in various ritual settings. This popularization has meant that its use is becoming common in retreats where ayahuasca is also being consumed. While from a physiological perspective the separate use of each of these preparations is quite safe, combining these two substances is dangerous and can be deadly.
There are at least two cases of deaths documented in the medical literature where the combination of Bufo alvarius with harmalines, compounds present in ayahuasca, was the cause. (The International Center for Ethnobotanical Education, Research & Service (ICEERS), 26.05.2017)
http://news.iceers.org/2017/05/alert-bufo-alvarius-and-ayahuasca/