Two novel compounds powerfully suppressed animals’ pain responses, while producing little or none of the respiratory depression and liability for misuse and abuse associated with morphine and other typical opioids. One of the compounds was ex…

Endogenous opioids regulate moment-to-moment neuronal communication and excitability. Winters, B. L. et al. Nat. Commun. 8, 14611 doi: 10.1038/ncomms14611 (2017). http://www.nature.com/articles/ncomms14611

Boosting natural brain opioids may be a better way to treat disabling emotions, says new research revealing their role in regulating critical brain circuits affecting fear and anxiety. Published in Nature Communications by University of Sydney scho…

Abhängigkeit von verschreibungspflichtigen Opioiden - Prävention, Diagnostik und Therapie Dependence on prescription opioids—prevention, diagnosis and treatment Dtsch Arztebl Int 2016; 113(13): 213-20; DOI: 10.3238/arztebl.201…

An advisory panel convened by the Food and Drug Administration to evaluate the health risks of the powerful opioid painkiller Opana ER (Oxymorphone retard, Anmerkung Forum Substitutionspraxis) says that the danger it poses as a drug of abuse ou…

Joint Meeting of the Drug Safety and Risk Management (DSaRM) Advisory Committee and the Anesthetic and Analgesic Drug Products Advisory Committee (AADPAC) Meeting March 13 -14, 2017 https://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeet…