Medical Cannabis For Endometriosis: What Does The Evidence Tell Us?

Endometriosis is a chronic condition where tissue similar to the lining of the uterus grows outside of it, causing scarring, inflammation, and often debilitating pelvic pain. Approximately 10% of women and girls of reproductive age are affected by endometriosis, and limited awareness and the wide range of symptoms can contribute to substantial delays in diagnosis.

No cure for endometriosis currently exists. Instead, treatment primarily focuses on pain management, commonly with nonsteroidal anti-inflammatory drugs, hormonal therapies, and surgery. However, the effectiveness of these options varies greatly, and many individuals continue to experience persistent pain.

Medical cannabis as a treatment option

Faced with minimal pain relief using existing therapies, people are increasingly considering how medical cannabis could help manage symptoms. The body’s endocannabinoid system is involved in processes including pain signalling, inflammation and immune function, and research suggests it may also play a role in endometriosis. Cannabinoids such as THC and CBD interact with this system and other biological pathways involved in pain and inflammation, providing a rationale for further investigation of their potential therapeutic effects. (Drug Science, UK, 01.10.2026)

https://www.drugscience.org.uk/medical-cannabis-for-endometriosis-what-does-the-evidence-tell-us