Sedative ‘dex’ is replacing ‘tranq’ in illegal drug supply and causing excruciating withdrawal - Medetomidine, the new adulterant to illegal fentanyl, can damage heart and brain 

Sedative ‘dex’ is replacing ‘tranq’ in illegal drug supply and causing excruciating withdrawal - Medetomidine, the new adulterant to illegal fentanyl, can damage heart and brain 

The era of “tranq” may be ending.

But tranq, as the powerful veterinary tranquilizer xylazine is known in the illicit drug supply, is being replaced at least in part by a dangerous new sedative: medetomidine. In the past year, the anesthetic has become an increasingly common element in the drug supply, with cities and states including Philadelphia, Pittsburgh, Chicago, and San Francisco reporting cases of medetomidine-involved overdoses. (Stat News, USA, 01.05.2025)

https://www.statnews.com/2025/05/01/medetomidine-replacing-xylazine-in-fentanyl-increases-overdose-danger-withdrawal-risks