Are Opioid Agonist Treatments Effective in the Fentanyl Era?

Are Opioid Agonist Treatments Effective in the Fentanyl Era?

Opioid agonist treatments (OATs) such as methadone and buprenorphine-naloxone are standard therapy for opioid use disorder, but treatment duration is decreasing as fentanyl becomes more prevalent in the illicit opioid supply. Given that retention in OAT is a core measurement of treatment effectiveness, the finding underscores the urgent need for research and policy changes, according to a population-based, retrospective cohort analysis from Ontario. (Medscape, USA, 14.07.2025)

https://www.medscape.com/viewarticle/are-opioid-agonist-treatments-effective-fentanyl-era-2025a1000iiz