A- A A+

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid. 

Vandeputte, M.M., Krotulski, A.J., Walther, D. et al.

Arch Toxicol 96, 1845–1863 (2022). doi.org/10.1007/s00204-022-03276-4

https://link.springer.com/article/10.1007/s00204-022-03276-4

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid. 

Vandeputte, M.M., Krotulski, A.J., Walther, D. et al.

Arch Toxicol 96, 1845–1863 (2022). doi.org/10.1007/s00204-022-03276-4

https://link.springer.com/article/10.1007/s00204-022-03276-4

Synthetic opioids: a review and clinical update. 

Shafi A, Berry AJ, Sumnall H, Wood DM, Tracy DK. 

Ther Adv Psychopharmacol. 2022 Dec 10;12:20451253221139616. doi: 10.1177/20451253221139616. PMID: 36532866; PMCID: PMC9747888.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747888/

Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches. 

Peeters LEJ, Vleut IT, Tan GE, Croes EA, Bethlehem C. 

Forensic Toxicol. 2022 Jan;40(1):199-203. doi: 10.1007/s11419-021-00598-3. Epub 2021 Oct 6. PMID: 36454494; PMCID: PMC9715521.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715521/

Fentanyl Overdose. 

Walter K. 

JAMA. 2022 Dec 2. doi: 10.1001/jama.2022.22462. Epub ahead of print. PMID: 36459152.

https://jamanetwork.com/journals/jama/fullarticle/2799344

Characteristics and context of fentanyl test strip use among syringe service clients in southern Wisconsin. 

Tilhou AS, Birstler J, Baltes A, Salisbury-Afshar E, Malicki J, Chen G, Brown R. 

Harm Reduct J. 2022 Dec 15;19(1):142. doi: 10.1186/s12954-022-00720-7. PMID: 36522777; PMCID: PMC9753354.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753354/

Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe. 

Jobski K, Bantel C, Hoffmann F. 

Eur J Clin Pharmacol. 2022 Dec 16. doi: 10.1007/s00228-022-03431-x. Epub ahead of print. PMID: 36525039.

https://link.springer.com/article/10.1007/s00228-022-03431-x

Pediatric Edible Cannabis Exposures and Acute Toxicity: 2017-2021. 

Tweet MS, Nemanich A, Wahl M. 

Pediatrics. 2023 Jan 3:e2022057761. doi: 10.1542/peds.2022-057761. Epub ahead of print. PMID: 36594224.

https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-057761/190427/Pediatric-Edible-Cannabis-Exposures-and-Acute?autologincheck=redirected

Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028).

Mboumba Bouassa RS, Needham J, Nohynek D, Singer J, Lee T, Bobeuf F, Samarani S, Del Balso L, Paisible N, Vertzagias C, Sebastiani G, Margolese S, Mandarino E, Klein M, Lebouché B, Cox J, Brouillette MJ, Routy JP, Szabo J, Thomas R, Huchet E, Vigano A, Jenabian MA, Costiniuk CT. 

Biomedicines. 2022 Dec 7;10(12):3168. doi: 10.3390/biomedicines10123168. PMID: 36551926; PMCID: PMC9775551.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775551/

SAMHSA Announces National Survey on Drug Use and Health (NSDUH) Results Detailing Mental Illness and Substance Use Levels in 2021

2021 NSDUH report includes selected estimates by race, ethnicity, and age and is the most comprehensive key findings report to date. (SAMHSA - Substance Abuse and Mental Health Services Administration, USA, 04.01.2023)

https://www.samhsa.gov/newsroom/press-announcements/20230104/samhsa-announces-nsduh-results-detailing-mental-illness-substance-use-levels-2021

Opioid-Associated Amnestic Syndrome Progressing to Diffuse Leukoencephalopathy. 

Meng D, Randhawa J. 

Neurohospitalist. 2023 Jan;13(1):109-110. doi: 10.1177/19418744211045862. Epub 2022 Oct 10. PMID: 36531854; PMCID: PMC9755609.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755609/

Pharmacological Interventions for Opioid-Induced Hyperalgesia: A Scoping Review of Preclinical Trials. 

Koponen ME, Forget P. 

J Clin Med. 2022 Nov 29;11(23):7060. doi: 10.3390/jcm11237060. PMID: 36498635; PMCID: PMC9735807.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735807/

Psychiatric Comorbidity, Psychosocial Problems, and Functioning of People Who Inject Opioids: An Observational Study. 

Farooqui AM, Arya A, Singh A, Dalal PK. 

Addict Health. 2022 Jul;14(3):218-223. doi: 10.34172/ahj.2022.1310. Epub 2022 Jul 29. PMID: 36544978; PMCID: PMC9743822.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743822/

Evaluation of the Impact of HIV Serostatus on the Hepatitis C Virus Care Cascade and Injection Drug Use Among Persons Initiating Medication Treatment for Opioid Use Disorder. 

Lier AJ, Vander Wyk B, Di Paola A, Springer SA. 

Open Forum Infect Dis. 2022 Nov 14;9(11):ofac624. doi: 10.1093/ofid/ofac624. PMID: 36467300; PMCID: PMC9709708.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709708/

Evaluation of the Impact of HIV Serostatus on the Hepatitis C Virus Care Cascade and Injection Drug Use Among Persons Initiating Medication Treatment for Opioid Use Disorder. 

Lier AJ, Vander Wyk B, Di Paola A, Springer SA. 

Open Forum Infect Dis. 2022 Nov 14;9(11):ofac624. doi: 10.1093/ofid/ofac624. PMID: 36467300; PMCID: PMC9709708.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709708/

Development and Validation of a Risk Prediction Tool to Identify People at Greater Risk of Having Hepatitis C among Drug Users. 

Huang G, Cheng W, Xu Y, Yang J, Jiang J, Pan X, Zhou X, Jiang J, Chai C. 

Int J Environ Res Public Health. 2022 Nov 25;19(23):15677. doi: 10.3390/ijerph192315677. PMID: 36497751; PMCID: PMC9738321.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738321/

Empfehlungen für die Nachsorge von Patientinnen/Patienten mit ausgeheilter Hepatitis C

Bobzin C, Bösiger Ch, Bruggmann P et al.

Swiss Med Forum. 2021;21(1112):184-186, Veröffentlichung: 17.03.2021, doi.org/10.4414/smf.2021.08756 

https://medicalforum.ch/de/detail/doi/smf.2021.08756

HCV elimination in a Swiss opioid agonist therapy programme - a cohort study. 

Bregenzer A, Krismer C, Wendel S, Roser P, Fux CA. 

Swiss Med Wkly. 2022 Dec 9;152:40009. doi: 10.57187/smw.2022.40009. PMID: 36509421.

https://smw.ch/index.php/smw/article/view/3257

Hep Voice December 2022, Issue 

Hrsg.: WHA – World Hepatitis Alliance, Funders: https://www.worldhepatitisalliance.org/funders/

https://www.worldhepatitisalliance.org/news/hep-voice-december-2022/

Substance Use Stigma and Community Drug Checking: A Qualitative Study Examining Barriers and Possible Responses. 

Davis S, Wallace B, Van Roode T, Hore D. 

Int J Environ Res Public Health. 2022 Nov 30;19(23):15978. doi: 10.3390/ijerph192315978. PMID: 36498052; PMCID: PMC9740784.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740784/

Everywhere and for everyone: proportionate universalism as a framework for equitable access to community drug checking. 

Wallace B, van Roode T, Burek P, Hore D, Pauly B. 

Harm Reduct J. 2022 Dec 20;19(1):143. doi: 10.1186/s12954-022-00727-0. PMID: 36539747; PMCID: PMC9763810.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763810/

An observational study of the extent of naloxone furnishing in California Central Valley community pharmacies. 

Banawis M, Mah G, Mohsin R, Pobre J, Tracy D, Song AV, Apollonio DE. 

J Am Pharm Assoc (2003). 2022 Nov 2:S1544-3191(22)00376-4. doi: 10.1016/j.japh.2022.10.028. Epub ahead of print. PMID: 36476261.

https://www.japha.org/article/S1544-3191(22)00376-4/fulltext

Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precision Amino-Acid Enkephalinase Inhibition Therapy (KB220) as a Frontline Modality Instead of Potent Opioids. 

Ceccanti M, Blum K, Bowirrat A, Dennen CA, Braverman ER, Baron D, Mclaughlin T, Giordano J, Gupta A, Downs BW, Bagchi D, Barh D, Elman I, Thanos PK, Badgaiyan RD, Edwards D, Gold MS. 

J Pers Med. 2022 Dec 6;12(12):2015. doi: 10.3390/jpm12122015. PMID: 36556236; PMCID: PMC9782293.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782293/

Association of medication-assisted treatment and short acting opioids with newborn head circumference and birth weight. 

Cutler, A.J., Cox, D.F., Gabrielson, S.M.B. et al.

J Perinatol (2022). doi.org/10.1038/s41372-022-01579-z

Abstract

https://www.nature.com/articles/s41372-022-01579-z#citeas

Understanding the effects of opioids vs non-opioids in the treatment of neonatal abstinence syndrome, an in vitro model. 

Sithisarn T, Legan SJ, Westgate PM, Bada HS, Wilson ME. 

Front Pediatr. 2022 Nov 22;10:1068330. doi: 10.3389/fped.2022.1068330. PMID: 36483468; PMCID: PMC9723166.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723166/

Neonatal abstinence syndrome hospitalizations in Canada: a descriptive study. 

Plouffe R, Grywacheski V, Luo W, Nelson C, Orpana H. 

Can J Public Health. 2022 Dec 8:1–10. doi: 10.17269/s41997-022-00726-5. Epub ahead of print. PMID: 36482143; PMCID: PMC9734797.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734797/

Behavioral Outcomes of Children With In-Utero Opioid Exposure Age 2-7 and Parenting Self-Efficacy. 

Arter S, Kiel E, McAllister J, Hay MC. 

J Am Psychiatr Nurses Assoc. 2022 Dec 7:10783903221139840. doi: 10.1177/10783903221139840. Epub ahead of print. PMID: 36475408.

https://journals.sagepub.com/doi/10.1177/10783903221139840

Discontinuation of opioid agonist treatment following release from prison in a cohort of men who injected drugs prior to imprisonment in Victoria, Australia: A discrete-time survival analysis. 

Curtis M, Dietze P, Wilkinson AL, Agius PA, Stewart AC, Cossar RD, Butler T, Walker S, Kirwan A, Winter RJ, Stoové M. 

Drug Alcohol Depend. 2023 Jan 1;242:109730. doi: 10.1016/j.drugalcdep.2022.109730. Epub 2022 Dec 7. PMID: 36516552.

https://www.sciencedirect.com/science/article/pii/S0376871622004677

Addressing Stigma is Not Enough. 

Amon JJ, Sun N, Iovita A, Jurgens R, Csete J. 

Health Hum Rights. 2022 Dec;24(2):111-114. PMID: 36579301; PMCID: PMC9790942.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790942/

Temporal associations between depressive features and self-stigma in people with substance use disorders related to heroin, amphetamine, and alcohol use: a cross-lagged analysis. 

Saffari M, Chang KC, Chen JS, Chang CW, Chen IH, Huang SW, Liu CH, Lin CY, Potenza MN. 

BMC Psychiatry. 2022 Dec 21;22(1):815. doi: 10.1186/s12888-022-04468-z. PMID: 36544132; PMCID: PMC9768939.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768939/