| Hans-Günter Meyer-Thompson | HIV
Novel mechanism of immune activation in HIV-exposed, seronegative people who inject drugs
Novel mechanism of immune activation in HIV-exposed, seronegative people who inject drugs
According to new research from The Wistar Institute, the S100A14 protein is expressed at higher levels in people who inject drugs and remain uninfected despite many years of high-risk, needle sharing behavior in areas with high HIV prevalence. The protein mediates activation of a type of immune cell called natural killer cells (NK), which play a key role in the host immune defense during the earliest phases of viral infection. These results were published in the journal JAIDS. (Wistar Institute, USA, 13.11.2018)
https://medicalxpress.com/news/2018-11-mechanism-immune-hiv-exposed-seronegative-people.html