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USA-New York. Opioid Addiction Knows No Color, but Ist Treatment Does

On a street lined with garbage trucks, in an industrial edge of Brooklyn, dozens of people started filing into an unmarked building before the winter sun rose. Patients gather here every day to visit the Vincent Dole Clinic, where they are promised relief from their cravings and from the constant search for heroin on the streets. (NYT, 12.01.2018)

https://www.nytimes.com/2018/01/12/nyregion/opioid-addiction-knows-no-color-but-its-treatment-does.html

USA. Buprenorphine and Methadone Dispensing in New York City.

Tuazon E, Kunins H, Paone D.

New York City, Department of Health and Mental Hygiene: Epi Data Brief (96); November 2017.

Buprenorphine and methadone are opioid agonist medications that are both safe and effective in the treatment of opioid use disorders . Methadone dispensing has been available through certified New York State Office of Alcoholism and Substance Abuse Services (OASAS) Opioid Treatment Programs in New York City (NYC) since the late 1970s.

Buprenorphine has been approved for treatment of opioid use disorders since 2002, and is now available by prescription from physicians, nurse practitioners, and physician assistants trained and approved to prescribe it.

In 2016, there were 69 OASAS-certified opioid treatment programs in NYC with a capacity to dispense methadone to approximately 32,000 patients with opioid use disorders.

(...) Most new patients in methadone treatment were Latino and Black or African-American (50% and 20%, respectively). One in three (27%) new patients in methadone treatment were White.

https://www1.nyc.gov/assets/doh/downloads/pdf/epi/databrief96.pdf

Cost-effectiveness of Methadone Maintenance Treatment Centers in Prevention of Human Immunodeficiency Virus Infection.

Pourkhajoei S, Barouni M, Noroozi A, Hajebi A, Amini S, Karamouzian M, Sharifi H.

Addict Health. 2017 Apr;9(2):81-87.

http://ahj.kmu.ac.ir/index.php/ahj/article/view/458/331

The Evaluation of Relationship between Sexual Self-concept and Sexual Dysfunction in Individuals Undergoing Methadone Maintenance Treatment.

Rajabizadeh G, Yazdanpanah F, Ramezani MA.

Addict Health. 2017 Apr;9(2):88-95.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742415/

Changing the Treatment Direction for Opiate Addiction: Dr. Dole's Research.

Joseph H, Woods JS.

Subst Use Misuse. 2017 Dec 11:1-13. doi: 10.1080/10826084.2017.1400069.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29227710

Alcohol use disorders are associated with increased HIV risk behaviors in cocaine-dependent methadone patients.

Meredith SE, Rash CJ, Petry NM.

J Subst Abuse Treat. 2017 Dec;83:10-14. doi: 10.1016/j.jsat.2017.09.016.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29129191

Trends in the Use of Methadone, Buprenorphine, and Extended-Release Naltrexone at Substance Abuse Treatment Facilities: 2003-2015 (Update).

Alderks CE.

The CBHSQ Report. Rockville (MD): Substance Abuse and Mental Health Services Administration (US); 2013-.

https://www.ncbi.nlm.nih.gov/books/NBK469748/

Long QTc During Methadone Maintenance: Contributors and Interventions Over 4 Years.

Westermeyer J, Thuras P, Yoon G, Batres-Y-Carr T.

J Nerv Ment Dis. 2017 Dec;205(12):925-930. doi: 10.1097/NMD.0000000000000757.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29076956

Customized recommendations and reminder text messages for automated, computer-based treatment during methadone.

Moore, B. A., Buono, F. D., Printz, D. M. B., Lloyd, D. P., Fiellin, D. A., Cutter, C. J., . . . Barry, D. T. (2017). 

Experimental and Clinical Psychopharmacology, 25(6), 485-495. doi.org/10.1037/pha0000149

Abstract

http://psycnet.apa.org/record/2017-55847-007

Arrhythmia associated with buprenorphine and methadone reported to the Food and Drug Administration.

Kao DP, Haigney MC, Mehler PS, Krantz MJ.

Addiction. 2015 Sep;110(9):1468-75. doi: 10.1111/add.13013.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521976/

Plasma Testosterone and Sexual Function in Southeast Asian Men Receiving Methadone and Buprenorphine Maintenance Treatment.

Yee A, Loh HS, Danaee M, Riahi S, Ng CG, Sulaiman AH.

J Sex Med. 2017 Dec 20. pii: S1743-6095(17)31853-2. doi: 10.1016/j.jsxm.2017.12.004.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29275046

Oxytocin protocol appears workable and safe for methadone patients who use cocaine

Some 30 to 60 percent of patients in methadone maintenance therapy (MMT) for opioid use disorders use cocaine. Compared to other MMT patients, those who use cocaine have higher rates of relapse and mortality. Studies with animals have suggested that the hormone oxytocin could be doubly helpful to these patients, by reducing the addictive effects of both opioids and cocaine. Now, researchers supported by the National Institute on Drug Abuse have developed a protocol for adjunctive oxytocin treatment, and a pilot study has indicated that it is workable and safe for MMT patients. (NIDA, Science Highlight, 09.01.2018)

https://www.drugabuse.gov/news-events/latest-science/oxytocin-protocol-appears-workable-safe-methadone-patients-who-use-cocaine

From Narcotic to Normalizer: The Misperception of Methadone Treatment and the Persistence of Prejudice and Bias.

Woods JS, Joseph H.

Subst Use Misuse. 2017 Dec 13:1-7. doi: 10.1080/10826084.2017.1400068.

Abstract

https://www.ncbi.nlm.nih.gov/pubmed/29236562

Buprenorphine as a safe alternative to methadone in a patient with acquired long QT syndrome: a case report.

de Jong IM, de Ruiter GS.

Neth Heart J. 2013 May;21(5):249-52. doi: 10.1007/s12471-011-0073-9.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636332/

Characteristics of Methadone Intoxicated Children Presenting to Emergency Department; a Cross Sectional Study.

Kashani P, Safari S, Hatamabadi H, Arhami Dolatabadi A, Manouchehrifar M, Dokht Tabrizi M.

Emerg (Tehran). 2017;5(1):e80. doi: 10.22037/emergency.v5i1.18780.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703757/

Increasing diversion of methadone in Vancouver, Canada, 2005-2015.

Reddon H, Ho J, DeBeck K, Milloy MJ, Liu Y, Dong H, Ahamad K, Wood E, Kerr T, Hayashi K.

J Subst Abuse Treat. 2018 Feb;85:10-16. doi: 10.1016/j.jsat.2017.11.010.

https://www.ncbi.nlm.nih.gov/pubmed/29291766