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The early impact of COVID-19 on the incidence, prevalence, and severity of alcohol use and other drugs: A systematic review. 

Schmidt RA, Genois R, Jin J, Vigo D, Rehm J, Rush B. 

Drug Alcohol Depend. 2021 Sep 22;228:109065. doi: 10.1016/j.drugalcdep.2021.109065. Epub ahead of print. PMID: 34600257; PMCID: PMC8455354. 


The Association Between Substance Use Disorder and Depression During the COVID-19 Lockdown in Spain and the Moderating Role of Social Support: a Cross-Sectional Study

Faris LH, Gabarrell-Pascuet A, Felez-Nobrega M, Cristóbal-Narváez P, Mortier P, Vilagut G, Olaya B, Alonso J, Haro JM, López-Carrilero R, Domènech-Abella J.

Int J Ment Health Addict. 2021 Sep 27:1-11. doi: 10.1007/s11469-021-00651-7. Epub ahead of print. PMID: 34602912; PMCID: PMC8475446.


Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic 

Published online: October 8, 2021 

COVID-19 Mental Disorders Collaborators 

The Lancet 


Suchtkrank in der Pandemie? – COVID-19 und Abhängigkeitserkrankungen / Addicted During Pandemic? – COVID-19 and Addictive Disorders

Beate Erbas, Hannah Strauch

Gesundheitswesen, DOI: 10.1055/a-1547-6948



Therapeutic potential of long-acting opioids and opioid antagonists for SARS-CoV-2 infection. 

Eagleton M, Stokes S, Fenton F, Keenan E. 

Br J Anaesth. 2021 Sep 6:S0007-0912(21)00553-5. doi: 10.1016/j.bja.2021.08.022. Epub ahead of print. PMID: 34556330; PMCID: PMC8418909.


Drug consumption during prolonged lockdown due to Covid-19 as observed in French addiction center. 

Chappuy M, Peyrat M, Lejeune O, Duvernay N, David B, Joubert P, Lack P. 

Therapie. 2021 Jul-Aug;76(4):379-382. doi: 10.1016/j.therap.2021.01.053. Epub 2021 Jan 20. PMID: 33516544; PMCID: PMC7817436.


Substance and Internet use during the COVID-19 pandemic in China. 

Huang Q, Chen X, Huang S, Shao T, Liao Z, Lin S, Li Y, Qi J, Cai Y, Shen H. 

Transl Psychiatry. 2021 Sep 23;11(1):491. doi: 10.1038/s41398-021-01614-1. PMID: 34556627; PMCID: PMC8459580.


Semper Aliquid Haeret. 

Kiefer F, Goudriaan AE. 

Eur Addict Res. 2021;27(4):237-238. doi: 10.1159/000517138. Epub 2021 May 28. PMID: 34052803.


A systematic review and meta-analysis on the prevalence of stigma in infectious diseases, including COVID-19: a call to action. 

Yuan K, Huang XL, Yan W, Zhang YX, Gong YM, Su SZ, Huang YT, Zhong Y, Wang YJ, Yuan Z, Tian SS, Zheng YB, Fan TT, Zhang YJ, Meng SQ, Sun YK, Lin X, Zhang TM, Ran MS, Wong SY, Rüsch N, Shi L, Bao YP, Lu L. 

Mol Psychiatry. 2021 Sep 27:1–15. doi: 10.1038/s41380-021-01295-8. Epub ahead of print. PMID: 34580416; PMCID: PMC8475479.


Associations of Substance Use With Behavioral Adherence to Centers for Disease Control and Prevention Guidelines for COVID-19 Mitigation: Survey Study. 

Monnig MA, Treloar Padovano H, Sokolovsky AW, DeCost G, Aston ER, Haass-Koffler CL, Szapary C, Moyo P, Avila JC, Tidey JW, Monti PM, Ahluwalia JS. 

JMIR Public Health Surveill. 2021 Sep 21. doi: 10.2196/29319. Epub ahead of print. PMID: 34591780.


Mental Health-Related Emergency Department Visits in Adolescents Before and During the COVID-19 Pandemic: A Multicentric Retrospective Study. 

Chadi N, Spinoso-Di Piano C, Osmanlliu E, Gravel J, Drouin O. 

J Adolesc Health. 2021 Aug 5:S1054-139X(21)00393-1. doi: 10.1016/j.jadohealth.2021.07.036. Epub ahead of print. PMID: 34462192; PMCID: PMC8421028.


Mental Health and Substance Use Among Adults with Disabilities During the COVID-19 Pandemic - United States, February-March 2021. 

Czeisler MÉ, Board A, Thierry JM, Czeisler CA, Rajaratnam SMW, Howard ME, Clarke KEN. 

MMWR Morb Mortal Wkly Rep. 2021 Aug 27;70(34):1142-1149. doi: 10.15585/mmwr.mm7034a3. PMID: 34437518; PMCID: PMC8389385.


People with substance use disorders may be at higher risk for SARS-CoV-2 breakthrough infections 

Co-occurring health disorders appear to contribute to increased risk, NIH study suggests. (NIH/National Institute on Drug Abuse/EurekaAlert, USA, 06.10.2021)


National and State Trends in Anxiety and Depression Severity Scores Among Adults During the COVID-19 Pandemic — United States, 2020–2021. 

Jia H, Guerin RJ, Barile JP, et al. 

MMWR Morb Mortal Wkly Rep. ePub: 5 October 2021. doi.org/10.15585/mmwr.mm7040e3


Psychotropics and COVID-19: An analysis of safety and prophylaxis. 

Javelot H, Straczek C, Meyer G, Gitahy Falcao Faria C, Weiner L, Drapier D, Fakra E, Fossati P, Weibel S, Dizet S, Langrée B, Masson M, Gaillard R, Leboyer M, Llorca PM, Hingray C, Haffen E, Yrondi A. 

Encephale. 2021 Sep 2:S0013-7006(21)00171-8. doi: 10.1016/j.encep.2021.08.002. Epub ahead of print. PMID: 34548153; PMCID: PMC8410507.


COVID-19 and Substance Use in Adolescents. 

Lundahl LH, Cannoy C. 

Pediatr Clin North Am. 2021 Oct;68(5):977-990. doi: 10.1016/j.pcl.2021.05.005. Epub 2021 May 18. PMID: 34538307; PMCID: PMC8445753.


Impact of Psychiatric and Related Somatic Medications on the Duration and Severity of COVID-19: A Retrospective Explorative Multi-center Study from the German Metropolitan Ruhr-area. 

Bonnet U, Claus B, Schaefer M, Kuhn J, Nyhuis P, Scherbaum N, Brüne M, Wakili V, Juckel G. 

Pharmacopsychiatry. 2021 Sep 16. doi: 10.1055/a-1559-3904. Epub ahead of print. PMID: 34530483.



Telemedicine and current clinical practice trends in the COVID-19 pandemic. 

Wahezi SE, Kohan LR, Spektor B, Brancolini S, Emerick T, Fronterhouse JM, Luedi MM, Colon MA, Kitei PM, Anitescu M, Goeders NE, Patil S, Siddaiah H, Cornett EM, Urman RD, Kaye AD. 

Best Pract Res Clin Anaesthesiol. 2021 Oct;35(3):307-319. doi: 10.1016/j.bpa.2020.11.005. Epub 2020 Nov 16. PMID: 34511221; PMCID: PMC7667401.


Impact of COVID-19 pandemic on emergency department substance use screens and overdose presentations. 

Chandran K, Mazer-Amirshahi M, Shankar N, Desale S, Nelson L, Mete M.

Am J Emerg Med. 2021 Aug 26;50:472-476. doi: 10.1016/j.ajem.2021.08.058. Epub ahead of print. PMID: 34509745; PMCID: PMC8387574.


COVID-19 and the Drug Overdose Crisis

Uncovering the Deadliest Months in the United States, January-July 2020

Joseph Friedman, MPH; Samir Akre, BS

Am J Public Health. 2021;111(7):1284-1291.


Comparison of Characteristics of Deaths From Drug Overdose Before vs During the COVID-19 Pandemic in Rhode Island. 

Macmadu A, Batthala S, Correia Gabel AM, et al.

JAMA Netw Open. 2021;4(9):e2125538. doi:10.1001/jamanetworkopen.2021.25538


State lockdown policies, mental health symptoms, and using substances. 

Das A, Singh P, Bruckner TA. 

Addict Behav. 2021 Aug 12;124:107084. doi: 10.1016/j.addbeh.2021.107084. Epub ahead of print. PMID: 34507184; PMCID: PMC8358101.


A randomized controlled trial of a therapeutic relational agent for reducing substance misuse during the COVID-19 pandemic. 

Prochaska JJ, Vogel EA, Chieng A, Baiocchi M, Maglalang DD, Pajarito S, Weingardt KR, Darcy A, Robinson A. 

Drug Alcohol Depend. 2021 Aug 27;227:108986. doi: 10.1016/j.drugalcdep.2021.108986. Epub ahead of print. PMID: 34507061; PMCID: PMC8423936.


The growing field of digital psychiatry: current evidence and the future of apps, social media, chatbots, and virtual reality. 

Torous J, Bucci S, Bell IH, Kessing LV, Faurholt-Jepsen M, Whelan P, Carvalho AF, Keshavan M, Linardon J, Firth J. 

World Psychiatry. 2021 Oct;20(3):318-335. doi: 10.1002/wps.20883. PMID: 34505369; PMCID: PMC8429349.


Gender, employment, and continuous pandemic as predictors of alcohol and drug consumption during the COVID-19. 

Levy I, Cohen-Louck K, Bonny-Noach H. 

Drug Alcohol Depend. 2021 Sep 2;228:109029. doi: 10.1016/j.drugalcdep.2021.109029. Epub ahead of print. PMID: 34500243; PMCID: PMC8411591.


Psychoactive Substance Use and Its Relationship to Stress, Emotional State, Depressive Symptomatology, and Perceived Threat During the COVID-19 Pandemic in Mexico. 

Martínez-Vélez NA, Tiburcio M, Natera Rey G, Villatoro Velázquez JA, Arroyo-Belmonte M, Sánchez-Hernández GY, Fernández-Torres M. 

Front Public Health. 2021 Aug 23;9:709410. doi: 10.3389/fpubh.2021.709410. PMID: 34497792; PMCID: PMC8419305.


Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal. 

Tanimoto, K., Hirota, K., Fukazawa, T. et al.

Sci Rep 11, 16629 (2021). doi.org/10.1038/s41598-021-96109-w


Drugs that mimic effects of cigarette smoke reduce SARS-CoV-2's ability to enter cells

Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking increases severity of the disease. (MedicalXpress, USA, 10.09.2021)


Projected long-term impact of the COVID-19 pandemic on hepatitis C outcomes in the United States: a modelling study. 

Barocas JA, Savinkina A, Lodi S, Epstein RL, Bouton TC, Sperring H, Hsu HE, Jacobson KR, Schechter-Perkins EM, Linas BP, White LF. 

Clin Infect Dis. 2021 Sep 9:ciab779. doi: 10.1093/cid/ciab779. Epub ahead of print. PMID: 34499124.