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Do gabapentin or pregabalin directly modulate the µ receptor? 

Manandhar P, Murnion BP, Grimsey NL, Connor M, Santiago M. 

PeerJ. 2021 Apr 12;9:e11175. doi: 10.7717/peerj.11175. PMID: 33954038; PMCID: PMC8048397.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048397/