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Heroin-assisted treatment of heroin-addicted patients normalizes regulatory T cells but does not restore CD4+ T cell proliferation. 

Hansen W, Luppus S, Barthel R, Chang DI, Broemstrup J, Zwarg T, Shibata J, Westendorf AM, Buer J, Scherbaum N. 

Addict Biol. 2020 Dec 17:e12998. doi: 10.1111/adb.12998. Epub ahead of print. PMID: 33336491.

https://onlinelibrary.wiley.com/doi/10.1111/adb.12998